Calcitriol Modulates the CD46 Pathway in T Cells

Rare variants in the CYP27B1 gene are associated with multiple sclerosis

(2011) Sreeram V. Ramagopalan et al.   ANNALS OF NEUROLOGY

Anti-CD25 (daclizumab) monoclonal antibody therapy in relapsing–remitting multiple sclerosis

(2011) Roland Martin   CLINICAL IMMUNOLOGY

1,25-Dihydroxyvitamin D3 acts directly on the T lymphocyte vitamin D receptor to inhibit experimental autoimmune encephalomyelitis

(2011) Christopher G. Mayne et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

1,25-Dihydroxyvitamin D3 inhibits proliferation but not the suppressive function of regulatory T cells in the absence of antigen-presenting cells

(2011) Ai-Leng Khoo et al.   IMMUNOLOGY

The Dynamic Processing of CD46 Intracellular Domains Provides a Molecular Rheostat for T Cell Activation

(2011) Siobhan Ni Choileain et al.   PLoS One

Vitamin D: modulator of the immune system

(2010) Femke Baeke et al.   CURRENT OPINION IN PHARMACOLOGY

A Defect of CD4+CD25+Regulatory T Cells in Inducing Interleukin-10 Production From CD4+T Cells Under CD46 Costimulation in Asthma Patients

(2010) Ya-Qing Xu et al.   JOURNAL OF ASTHMA

The Vitamin D Analog, TX527, Promotes a Human CD4+CD25highCD127low Regulatory T Cell Profile and Induces a Migratory Signature Specific for Homing to Sites of Inflammation

(2010) F. Baeke et al.   JOURNAL OF IMMUNOLOGY

Vitamin D and multiple sclerosis

(2010) Alberto Ascherio et al.   LANCET NEUROLOGY

Complement regulator CD46 temporally regulates cytokine production by conventional and unconventional T cells

(2010) John Cardone et al.   NATURE IMMUNOLOGY

Vitamin D controls T cell antigen receptor signaling and activation of human T cells

(2010) Marina Rode von Essen et al.   NATURE IMMUNOLOGY

A phase I/II dose-escalation trial of vitamin D3 and calcium in multiple sclerosis

(2010) J. M. Burton et al.   NEUROLOGY

1,25-Dihydroxyvitamin D3 Inhibits the Differentiation and Migration of TH17 Cells to Protect against Experimental Autoimmune Encephalomyelitis

(2010) Jae-Hoon Chang et al.   PLoS One

Safety and T Cell Modulating Effects of High Dose Vitamin D3 Supplementation in Multiple Sclerosis

(2010) Joost Smolders et al.   PLoS One

Vitamin D and Asthma

(2009) Graham Devereux et al.   AMERICAN JOURNAL OF RESPIRATORY AND CRITICAL CARE MEDICINE

Immunomodulatory effects of Vitamin D in multiple sclerosis

(2009) J. Correale et al.   BRAIN

Autophagy Induction by the Pathogen Receptor CD46

(2009) Pierre-Emmanuel Joubert et al.   Cell Host & Microbe

Dysfunction of IL-10-producing type 1 regulatory T cells and CD4+CD25+ regulatory T cells in a mimic model of human multiple sclerosis in Cynomolgus monkeys

(2009) Anlun Ma et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

1,25-Dihydroxyvitamin D3 and IL-2 Combine to Inhibit T Cell Production of Inflammatory Cytokines and Promote Development of Regulatory T Cells Expressing CTLA-4 and FoxP3

(2009) L. E. Jeffery et al.   JOURNAL OF IMMUNOLOGY

IL-10 suppressor activity andex vivo Tr1 cell function are impaired in multiple sclerosis

(2008) Ivan Martinez-Forero et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

1α,25-dihydroxyvitamin D3inhibits matrix metalloproteinases induced byMycobacterium tuberculosisinfection

(2008) Anna Coussens et al.   IMMUNOLOGY

Control of autoimmune diseases by the vitamin D endocrine system

(2008) Luciano Adorini et al.   Nature clinical practice. Rheumatology