Intensiometric biosensors visualize the activity of multiple small GTPases in vivo

Temporally precise labeling and control of neuromodulatory circuits in the mammalian brain

(2017) Dongmin Lee et al.   NATURE METHODS

De novo synaptogenesis induced by GABA in the developing mouse cortex

(2016) Won Chan Oh et al.   SCIENCE

Bright monomeric near-infrared fluorescent proteins as tags and biosensors for multiscale imaging

(2016) Daria M. Shcherbakova et al.   Nature Communications

Waves of actin and microtubule polymerization drive microtubule-based transport and neurite growth before single axon formation

(2016) Amy M Winans et al.   eLife

High-throughput analysis and protein engineering using microcapillary arrays

(2015) Bob Chen et al.   Nature Chemical Biology

Ratiometric biosensors based on dimerization-dependent fluorescent protein exchange

(2015) Yidan Ding et al.   NATURE METHODS

High-Sensitivity Measurements of Multiple Kinase Activities in Live Single Cells

(2014) Sergi Regot et al.   CELL

Spatiotemporal Control of Fibroblast Growth Factor Receptor Signals by Blue Light

(2014) Nury Kim et al.   CHEMISTRY & BIOLOGY

Optogenetic approaches to cell migration and beyond

(2014) Matthew Weitzman et al.   CURRENT OPINION IN CELL BIOLOGY

Illuminating cell signalling with optogenetic tools

(2014) Doug Tischer et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Light-inducible receptor tyrosine kinases that regulate neurotrophin signalling

(2014) Ki-Young Chang et al.   Nature Communications

Using Optogenetics to Interrogate the Dynamic Control of Signal Transmission by the Ras/Erk Module

(2013) Jared E. Toettcher et al.   CELL

Near-infrared fluorescent proteins for multicolor in vivo imaging

(2013) Daria M Shcherbakova et al.   NATURE METHODS

An Improved Ras Sensor for Highly Sensitive and Quantitative FRET-FLIM Imaging

(2013) Ana F. Oliveira et al.   PLoS One

Optogenetic reporters

(2012) Spencer C. Alford et al.   BIOLOGY OF THE CELL

A Fluorogenic Red Fluorescent Protein Heterodimer

(2012) Spencer C. Alford et al.   CHEMISTRY & BIOLOGY

Cooperative Activation of PI3K by Ras and Rho Family Small GTPases

(2012) Hee Won Yang et al.   MOLECULAR CELL

Postsynaptic signaling during plasticity of dendritic spines

(2012) Hideji Murakoshi et al.   TRENDS IN NEUROSCIENCES

Dimerization-Dependent Green and Yellow Fluorescent Proteins

(2012) Spencer C. Alford et al.   ACS Synthetic Biology

Spatiotemporal Regulation of Small GTPases as Revealed by Probes Based on the Principle of Förster Resonance Energy Transfer (FRET): Implications for Signaling and Pharmacology

(2011) Etsuko Kiyokawa et al.   Annual Review of Pharmacology and Toxicology

Loss of PSD-95 Enrichment Is Not a Prerequisite for Spine Retraction

(2011) G. F. Woods et al.   JOURNAL OF NEUROSCIENCE

Development of an optimized backbone of FRET biosensors for kinases and GTPases

(2011) Naoki Komatsu et al.   MOLECULAR BIOLOGY OF THE CELL

Local, persistent activation of Rho GTPases during plasticity of single dendritic spines

(2011) Hideji Murakoshi et al.   NATURE

Imaging the coordination of multiple signalling activities in living cells

(2011) Christopher M. Welch et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

High Cleavage Efficiency of a 2A Peptide Derived from Porcine Teschovirus-1 in Human Cell Lines, Zebrafish and Mice

(2011) Jin Hee Kim et al.   PLoS One

Patch-Based Nonlocal Functional for Denoising Fluorescence Microscopy Image Sequences

(2009) J. Boulanger et al.   IEEE TRANSACTIONS ON MEDICAL IMAGING

Spatiotemporal control of cell signalling using a light-switchable protein interaction

(2009) Anselm Levskaya et al.   NATURE

Coordination of Rho GTPase activities during cell protrusion

(2009) Matthias Machacek et al.   NATURE

Robust Neuronal Symmetry Breaking by Ras-Triggered Local Positive Feedback

(2008) Marc Fivaz et al.   CURRENT BIOLOGY