Integration of DNA methylation patterns and genetic variation in human pediatric tissues help inform EWAS design and interpretation

Principles and Challenges of Applying Epigenetic Epidemiology to Psychology

(2018) Meaghan J. Jones et al.   Annual Review of Psychology

A user's guide to the ambiguous word 'epigenetics'

(2018) John M. Greally   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Quantitation of the cellular content of saliva and buccal swab samples

(2018) Christiane Theda et al.   Scientific Reports

Associating cellular epigenetic models with human phenotypes

(2017) Tuuli Lappalainen et al.   NATURE REVIEWS GENETICS

Differential DNA methylation and lymphocyte proportions in a Costa Rican high longevity region

(2017) Lisa M. McEwen et al.   Epigenetics & Chromatin

Cross-tissue integration of genetic and epigenetic data offers insight into autism spectrum disorder

(2017) Shan V. Andrews et al.   Nature Communications

Epigenetics, cellular memory and gene regulation

(2016) Steven Henikoff et al.   CURRENT BIOLOGY

DNA methylation signature of human fetal alcohol spectrum disorder

(2016) Elodie Portales-Casamar et al.   Epigenetics & Chromatin

Genome-wide DNA methylation levels and altered cortisol stress reactivity following childhood trauma in humans

(2016) Lotte C. Houtepen et al.   Nature Communications

Epigenome-wide Association Studies and the Interpretation of Disease -Omics

(2016) Ewan Birney et al.   PLoS Genetics

Tobacco smoking differently influences cell types of the innate and adaptive immune system—indications from CpG site methylation

(2016) Mario Bauer et al.   Clinical Epigenetics

Distinct Epigenetic Effects of Tobacco Smoking in Whole Blood and among Leukocyte Subtypes

(2016) Dan Su et al.   PLoS One

Pubertal development in healthy children is mirrored by DNA methylation patterns in peripheral blood

(2016) Kristian Almstrup et al.   Scientific Reports

DNA methylation and healthy human aging

(2015) Meaghan J. Jones et al.   AGING CELL

Methylomic analysis of monozygotic twins discordant for childhood psychotic symptoms

(2015) Helen L Fisher et al.   Epigenetics

Interindividual methylomic variation across blood, cortex, and cerebellum: implications for epigenetic studies of neurological and neuropsychiatric phenotypes

(2015) Eilis Hannon et al.   Epigenetics

Bacterial infection remodels the DNA methylation landscape of human dendritic cells

(2015) Alain Pacis et al.   GENOME RESEARCH

Integrative analysis of 111 reference human epigenomes

(2015) Anshul Kundaje et al.   NATURE

Methylation QTLs in the developing brain and their enrichment in schizophrenia risk loci

(2015) Eilis Hannon et al.   NATURE NEUROSCIENCE

Concordant and discordant DNA methylation signatures of aging in human blood and brain

(2015) Pau Farré et al.   Epigenetics & Chromatin

Characterization of functional methylomes by next-generation capture sequencing identifies novel disease-associated variants

(2015) Fiona Allum et al.   Nature Communications

Long-range epigenetic regulation is conferred by genetic variation located at thousands of independent loci

(2015) Mathieu Lemire et al.   Nature Communications

Discordance of DNA Methylation Variance Between two Accessible Human Tissues

(2015) Ruiwei Jiang et al.   Scientific Reports

Tissue-Specific Effects of Genetic and Epigenetic Variation on Gene Regulation and Splicing

(2015) Maria Gutierrez-Arcelus et al.   PLoS Genetics

A varying T cell subtype explains apparent tobacco smoking induced single CpG hypomethylation in whole blood

(2015) Mario Bauer et al.   Clinical Epigenetics

DNA methylation changes of whole blood cells in response to active smoking exposure in adults: a systematic review of DNA methylation studies

(2015) Xu Gao et al.   Clinical Epigenetics

quantro: a data-driven approach to guide the choice of an appropriate normalization method

(2015) Stephanie Hicks et al.   GENOME BIOLOGY

Correlation of Smoking-Associated DNA Methylation Changes in Buccal Cells With DNA Methylation Changes in Epithelial Cancer

(2015) Andrew E. Teschendorff et al.   JAMA Oncology

DNA extracted from saliva for methylation studies of psychiatric traits: Evidence tissue specificity and relatedness to brain

(2014) Alicia K. Smith et al.   AMERICAN JOURNAL OF MEDICAL GENETICS PART B-NEUROPSYCHIATRIC GENETICS

Methylation quantitative trait loci (meQTLs) are consistently detected across ancestry, developmental stage, and tissue type

(2014) Alicia K Smith et al.   BMC GENOMICS

The effect of genotype and in utero environment on interindividual variation in neonate DNA methylomes

(2014) A. L. Teh et al.   GENOME RESEARCH

Illumina human exome genotyping array clustering and quality control

(2014) Yan Guo et al.   Nature Protocols

Meta-analysis of human methylomes reveals stably methylated sequences surrounding CpG islands associated with high gene expression

(2014) Rachel Edgar et al.   Epigenetics & Chromatin

Mosaic Epigenetic Dysregulation of Ectodermal Cells in Autism Spectrum Disorder

(2014) Esther R. Berko et al.   PLoS Genetics

Methylation QTLs Are Associated with Coordinated Changes in Transcription Factor Binding, Histone Modifications, and Gene Expression Levels

(2014) Nicholas E. Banovich et al.   PLoS Genetics

Leishmania donovani Infection Causes Distinct Epigenetic DNA Methylation Changes in Host Macrophages

(2014) Alexandra K. Marr et al.   PLoS Pathogens

Accounting for cellular heterogeneity is critical in epigenome-wide association studies

(2014) Andrew E Jaffe et al.   GENOME BIOLOGY

Global Analysis of DNA Methylation Variation in Adipose Tissue from Twins Reveals Links to Disease-Associated Variants in Distal Regulatory Elements

(2013) Elin Grundberg et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Buccals are likely to be a more informative surrogate tissue than blood for epigenome-wide association studies

(2013) Robert Lowe et al.   Epigenetics

Blood-based profiles of DNA methylation predict the underlying distribution of cell types

(2013) Devin C Koestler et al.   Epigenetics

DNA methylation contributes to natural human variation

(2013) H. Heyn et al.   GENOME RESEARCH

Charting a dynamic DNA methylation landscape of the human genome

(2013) Michael J. Ziller et al.   NATURE

Transcriptome and genome sequencing uncovers functional variation in humans

(2013) Tuuli Lappalainen et al.   NATURE

Recommendations for the design and analysis of epigenome-wide association studies

(2013) Karin B Michels et al.   NATURE METHODS

From promises to practical strategies in epigenetic epidemiology

(2013) Jonathan Mill et al.   NATURE REVIEWS GENETICS

Identification and systematic annotation of tissue-specific differentially methylated regions using the Illumina 450k array

(2013) Roderick C Slieker et al.   Epigenetics & Chromatin

Additional annotation enhances potential for biologically-relevant analysis of the Illumina Infinium HumanMethylation450 BeadChip array

(2013) Magda E Price et al.   Epigenetics & Chromatin

Passive and active DNA methylation and the interplay with genetic variation in gene regulation

(2013) Maria Gutierrez-Arcelus et al.   eLife

A beta-mixture quantile normalization method for correcting probe design bias in Illumina Infinium 450 k DNA methylation data

(2012) Andrew E. Teschendorff et al.   BIOINFORMATICS

DNA methylation arrays as surrogate measures of cell mixture distribution

(2012) Eugene Houseman et al.   BMC BIOINFORMATICS

Age-associated DNA methylation in pediatric populations

(2012) R. S. Alisch et al.   GENOME RESEARCH

Allele-specific FKBP5 DNA demethylation mediates gene–childhood trauma interactions

(2012) Torsten Klengel et al.   NATURE NEUROSCIENCE

Functions of DNA methylation: islands, start sites, gene bodies and beyond

(2012) Peter A. Jones   NATURE REVIEWS GENETICS

Analysing and interpreting DNA methylation data

(2012) Christoph Bock   NATURE REVIEWS GENETICS

Differential DNA Methylation in Purified Human Blood Cells: Implications for Cell Lineage and Studies on Disease Susceptibility

(2012) Lovisa E. Reinius et al.   PLoS One

Epigenome-Wide Scans Identify Differentially Methylated Regions for Age and Age-Related Phenotypes in a Healthy Ageing Population

(2012) Jordana T. Bell et al.   PLoS Genetics

Population-specificity of human DNA methylation

(2012) Hunter B Fraser et al.   GENOME BIOLOGY

Dissecting the regulatory architecture of gene expression QTLs

(2012) Daniel J Gaffney et al.   GENOME BIOLOGY

Evidence for age-related and individual-specific changes in DNA methylation profile of mononuclear cells during early immune development in humans

(2011) David J. Martino et al.   Epigenetics

High density DNA methylation array with single CpG site resolution

(2011) Marina Bibikova et al.   GENOMICS

Epigenome-wide association studies for common human diseases

(2011) Vardhman K. Rakyan et al.   NATURE REVIEWS GENETICS

Genome-wide mapping of imprinted differentially methylated regions by DNA methylation profiling of human placentas from triploidies

(2011) Ryan KC Yuen et al.   Epigenetics & Chromatin

Analysis of DNA Methylation in a Three-Generation Family Reveals Widespread Genetic Influence on Epigenetic Regulation

(2011) Jason Gertz et al.   PLoS Genetics

DNA methylation patterns associate with genetic and gene expression variation in HapMap cell lines

(2011) Jordana T Bell et al.   GENOME BIOLOGY

Principles and challenges of genome-wide DNA methylation analysis

(2010) Peter W. Laird   NATURE REVIEWS GENETICS

The DNA Methylome of Human Peripheral Blood Mononuclear Cells

(2010) Yingrui Li et al.   PLOS BIOLOGY

Abundant Quantitative Trait Loci Exist for DNA Methylation and Gene Expression in Human Brain

(2010) J. Raphael Gibbs et al.   PLoS Genetics

Epigenetic profiling of somatic tissues from human autopsy specimens identifies tissue- and individual-specific DNA methylation patterns

(2009) Hyang-Min Byun et al.   HUMAN MOLECULAR GENETICS

DNA methylation profiles in monozygotic and dizygotic twins

(2009) Zachary A Kaminsky et al.   NATURE GENETICS

Low early-life social class leaves a biological residue manifested by decreased glucocorticoid and increased proinflammatory signaling

(2009) G. E. Miller et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA