miR-146b promotes cell proliferation and increases chemosensitivity, but attenuates cell migration and invasion via FBXL10 in ovarian cancer

Major clinical research advances in gynecologic cancer in 2017

(2018) Dong Hoon Suh et al.   Journal of Gynecologic Oncology

In vitro and in vivo evaluation of folate receptor-targeted a novel magnetic drug delivery system for ovarian cancer therapy

(2018) Güliz Ak et al.   Artificial Cells Nanomedicine and Biotechnology

High-grade serous carcinoma of tubo-ovarian origin: recent developments

(2017) Naveena Singh et al.   HISTOPATHOLOGY

Up-regulated WDR5 promotes gastric cancer formation by induced cyclin D1 expression

(2017) Wei Sun et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Synergistic IL-6 and IL-8 paracrine signalling pathway infers a strategy to inhibit tumour cell migration

(2017) Hasini Jayatilaka et al.   Nature Communications

Complex Determinants of Epithelial: Mesenchymal Phenotypic Plasticity in Ovarian Cancer

(2017) Yuliya Klymenko et al.   Cancers

KDM2B/FBXL10 targets c-Fos for ubiquitylation and degradation in response to mitogenic stimulation

(2016) X-R Han et al.   ONCOGENE

Fbxl10 overexpression in murine hematopoietic stem cells induces leukemia involving metabolic activation and upregulation of Nsg2

(2015) T. Ueda et al.   BLOOD

Global miRNA expression analysis of serous and clear cell ovarian carcinomas identifies differentially expressed miRNAs including miR-200c-3p as a prognostic marker

(2014) Bente Vilming Elgaaen et al.   BMC CANCER

NDY1/KDM2B Functions as a Master Regulator of Polycomb Complexes and Controls Self-Renewal of Breast Cancer Stem Cells

(2014) F. Kottakis et al.   CANCER RESEARCH

PTD-mediated intracellular delivery of mutant NFAT minimum DNA binding domain inhibited the proliferation of T cells

(2014) Xia Liu et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

MicroRNA-146a and MicroRNA-146b Regulate Human Dendritic Cell Apoptosis and Cytokine Production by Targeting TRAF6 and IRAK1 Proteins

(2014) Haein Park et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

STAT3 Induction of miR-146b Forms a Feedback Loop to Inhibit the NF- B to IL-6 Signaling Axis and STAT3-Driven Cancer Phenotypes

(2014) M. Xiang et al.   Science Signaling

Regulation of Metastasis by microRNAs in Ovarian Cancer

(2014) Yongchao Wang et al.   Frontiers in Oncology

Integrated Analyses Identify a Master MicroRNA Regulatory Network for the Mesenchymal Subtype in Serous Ovarian Cancer

(2013) Da Yang et al.   CANCER CELL

The H3K4me3 Histone Demethylase Fbxl10 Is a Regulator of Chemokine Expression, Cellular Morphology, and the Metabolome of Fibroblasts

(2012) Andreas Janzer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

PTD-hFOXP3 protein acts as an immune regulator to convert human CD4+CD25−T cells to regulatory T-like cells

(2012) Xia Liu et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

KDM2b/JHDM1b, an H3K36me2-specific demethylase, is required for initiation and maintenance of acute myeloid leukemia

(2011) J. He et al.   BLOOD

Reduced proliferation and enhanced migration: Two sides of the same coin? Molecular mechanisms of metastatic progression by YB-1

(2011) Valentina Evdokimova et al.   CELL CYCLE

Forced expression of the histone demethylase Fbxl10 maintains self-renewing hematopoietic stem cells

(2011) Takaaki Konuma et al.   EXPERIMENTAL HEMATOLOGY

FGF-2 Regulates Cell Proliferation, Migration, and Angiogenesis through an NDY1/KDM2B-miR-101-EZH2 Pathway

(2011) Filippos Kottakis et al.   MOLECULAR CELL

miR-141 and miR-200a act on ovarian tumorigenesis by controlling oxidative stress response

(2011) Bogdan Mateescu et al.   NATURE MEDICINE

MicroRNA miR-146b-5p regulates signal transduction of TGF-β by repressing SMAD4 in thyroid cancer

(2011) M V Geraldo et al.   ONCOGENE

Migration of growth factor-stimulated epithelial and endothelial cells depends on EGFR transactivation by ADAM17

(2011) Thorsten Maretzky et al.   Nature Communications

microRNA-146b inhibits glioma cell migration and invasion by targeting MMPs

(2009) Hongping Xia et al.   BRAIN RESEARCH

Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression

(2009) D. L. Gibbons et al.   GENES & DEVELOPMENT

MicroRNA dynamics in the stages of tumorigenesis correlate with hallmark capabilities of cancer

(2009) P. Olson et al.   GENES & DEVELOPMENT

In vivo Switching of Human Melanoma Cells between Proliferative and Invasive States

(2008) K. S. Hoek et al.   CANCER RESEARCH

The H3K36 demethylase Jhdm1b/Kdm2b regulates cell proliferation and senescence through p15Ink4b

(2008) Jin He et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Expression of microRNA-146 suppresses NF-κB activity with reduction of metastatic potential in breast cancer cells

(2008) D Bhaumik et al.   ONCOGENE

MicroRNA Expression and Identification of Putative miRNA Targets in Ovarian Cancer

(2008) Neetu Dahiya et al.   PLoS One