Reactivation of TAp73 tumor suppressor by protoporphyrin IX, a metabolite of aminolevulinic acid, induces apoptosis in TP53-deficient cancer cells

Radiosensitizing Effect of 5-Aminolevulinic Acid and Protoporphyrin IX on Carbon-ion Beam Irradiation

(2018) TOMOKO KANEKO et al.   ANTICANCER RESEARCH

Dual inhibition of MDMX and MDM2 as a therapeutic strategy in leukemia

(2018) Luis A. Carvajal et al.   Science Translational Medicine

APR-246 reactivates mutant p53 by targeting cysteines 124 and 277

(2018) Qiang Zhang et al.   Cell Death & Disease

New uses for old drugs

(2018) Pan Pantziarka et al.   BMJ-British Medical Journal

New uses for old drugs

(2018) Pan Pantziarka et al.   BMJ-British Medical Journal

Global, Regional, and National Cancer Incidence, Mortality, Years of Life Lost, Years Lived With Disability, and Disability-Adjusted Life-Years for 29 Cancer Groups, 1990 to 2016

(2018) et al.   JAMA Oncology

Wild-type and mutant p53 differentially modulate miR-124/iASPP feedback following pohotodynamic therapy in human colon cancer cell line

(2017) Kuijie Liu et al.   Cell Death & Disease

The essential role of TAp73 in bortezomib-induced apoptosis in p53-deficient colorectal cancer cells

(2017) Yasamin Dabiri et al.   Scientific Reports

Novel therapeutic interventions for p53-altered tumors through manipulation of its family members, p63 and p73

(2015) Avinashnarayan Venkatanarayan et al.   CELL CYCLE

MDM2 mediates p73 ubiquitination: a new molecular mechanism for suppression of p73 function

(2015) Hong Wu et al.   Oncotarget

IAPP-driven metabolic reprogramming induces regression of p53-deficient tumours in vivo

(2014) Avinashnarayan Venkatanarayan et al.   NATURE

TAp73 suppresses tumor angiogenesis through repression of proangiogenic cytokines and HIF-1α activity

(2014) Marina Stantic et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

JNK–NQO1 axis drives TAp73-mediated tumor suppression upon oxidative and proteasomal stress

(2014) A Kostecka et al.   Cell Death & Disease

High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy

(2014) M Rossi et al.   Cell Death & Disease

Analysis of the oligomeric state and transactivation potential of TAp73α

(2013) L M Luh et al.   CELL DEATH AND DIFFERENTIATION

DNA Damage and Cell Cycle Arrest Induced by Protoporphyrin IX in Sarcoma 180 Cells

(2013) Qing Li et al.   CELLULAR PHYSIOLOGY AND BIOCHEMISTRY

TAp73-Mediated the Activation of C-Jun N-Terminal Kinase Enhances Cellular Chemosensitivity to Cisplatin in Ovarian Cancer Cells

(2012) Pingde Zhang et al.   PLoS One

Photodynamic therapy of cancer: An update

(2011) Patrizia Agostinis et al.   CA-A CANCER JOURNAL FOR CLINICIANS

p53 Transactivation and the Impact of Mutations, Cofactors and Small Molecules Using a Simplified Yeast-Based Screening System

(2011) Virginia Andreotti et al.   PLoS One

Targeting of p53 and its homolog p73 by protoporphyrin IX

(2010) Alicja Sznarkowska et al.   FEBS LETTERS

p63 and p73, the Ancestors of p53

(2010) V. Dotsch et al.   Cold Spring Harbor Perspectives in Biology

TAp73 knockout shows genomic instability with infertility and tumor suppressor functions

(2008) R. Tomasini et al.   GENES & DEVELOPMENT

Small-molecule RETRA suppresses mutant p53-bearing cancer cells through a p73-dependent salvage pathway

(2008) J. E. Kravchenko et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The impact of p53 and p73 on aneuploidy and cancer

(2008) Richard Tomasini et al.   TRENDS IN CELL BIOLOGY