The vesicular stomatitis virus-based Ebola virus vaccine: From concept to clinical trials

Six-Month Safety Data of Recombinant Vesicular Stomatitis Virus–Zaire Ebola Virus Envelope Glycoprotein Vaccine in a Phase 3 Double-Blind, Placebo-Controlled Randomized Study in Healthy Adults

(2017) Scott A. Halperin et al.   JOURNAL OF INFECTIOUS DISEASES

Efficacy and effectiveness of an rVSV-vectored vaccine in preventing Ebola virus disease: final results from the Guinea ring vaccination, open-label, cluster-randomised trial (Ebola Ça Suffit!)

(2017) Ana Maria Henao-Restrepo et al.   LANCET

A dose-dependent plasma signature of the safety and immunogenicity of the rVSV-Ebola vaccine in Europe and Africa

(2017) Angela Huttner et al.   Science Translational Medicine

Ebola and Marburg virus vaccines

(2017) Pierce Reynolds et al.   VIRUS GENES

Systems Vaccinology Identifies an Early Innate Immune Signature as a Correlate of Antibody Responses to the Ebola Vaccine rVSV-ZEBOV

(2017) Anne Rechtien et al.   Cell Reports

Safety and immunogenicity of rVSVΔG-ZEBOV-GP Ebola vaccine in adults and children in Lambaréné, Gabon: A phase I randomised trial

(2017) Selidji T. Agnandji et al.   PLOS MEDICINE

Dose-dependent T-cell Dynamics and Cytokine Cascade Following rVSV-ZEBOV Immunization

(2017) Christine Dahlke et al.   EBioMedicine

Use of Postexposure Prophylaxis After Occupational Exposure toZaire ebolavirus

(2016) Karen K. Wong et al.   CLINICAL INFECTIOUS DISEASES

Ebola virus vaccines – reality or fiction?

(2016) Chad E. Mire et al.   Expert Review of Vaccines

Efficacy of Vesicular Stomatitis Virus–Ebola Virus Postexposure Treatment in Rhesus Macaques Infected With Ebola Virus Makona

(2016) Andrea Marzi et al.   JOURNAL OF INFECTIOUS DISEASES

Human antibody repertoire after VSV-Ebola vaccination identifies novel targets and virus-neutralizing IgM antibodies

(2016) Surender Khurana et al.   NATURE MEDICINE

Circulating follicular T helper cells and cytokine profile in humans following vaccination with the rVSV-ZEBOV Ebola vaccine

(2016) Fouzia Farooq et al.   Scientific Reports

Animal models for ebolavirus countermeasures discovery: what defines a useful model?

(2015) Amy C Shurtleff et al.   Expert Opinion on Drug Discovery

A Single-Vector, Single-Injection Trivalent Filovirus Vaccine: Proof of Concept Study in Outbred Guinea Pigs

(2015) Chad E. Mire et al.   JOURNAL OF INFECTIOUS DISEASES

Efficacy and effectiveness of an rVSV-vectored vaccine expressing Ebola surface glycoprotein: interim results from the Guinea ring vaccination cluster-randomised trial

(2015) Ana Maria Henao-Restrepo et al.   LANCET

The effect of dose on the safety and immunogenicity of the VSV Ebola candidate vaccine: a randomised double-blind, placebo-controlled phase 1/2 trial

(2015) Angela Huttner et al.   LANCET INFECTIOUS DISEASES

VSV-EBOV rapidly protects macaques against infection with the 2014/15 Ebola virus outbreak strain

(2015) A. Marzi et al.   SCIENCE

A Recombinant Vesicular Stomatitis Virus-Based Lassa Fever Vaccine Protects Guinea Pigs and Macaques against Challenge with Geographically and Genetically Distinct Lassa Viruses

(2015) David Safronetz et al.   PLoS Neglected Tropical Diseases

Single-dose live-attenuated Nipah virus vaccines confer complete protection by eliciting antibodies directed against surface glycoproteins

(2014) Blair L. DeBuysscher et al.   VACCINE

Immunization with vesicular stomatitis virus vaccine expressing the Ebola glycoprotein provides sustained long-term protection in rodents

(2014) Gary Wong et al.   VACCINE

Antibodies are necessary for rVSV/ZEBOV-GP-mediated protection against lethal Ebola virus challenge in nonhuman primates

(2013) A. Marzi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Vesicular Stomatitis Virus-Based Vaccines Protect Nonhuman Primates against Bundibugyo ebolavirus

(2013) Chad E. Mire et al.   PLoS Neglected Tropical Diseases

Evaluation of attenuated VSVs with mutated M or/and G proteins as vaccine vectors

(2012) Xinkui Fang et al.   VACCINE

Recombinant Vesicular Stomatitis Virus Vaccine Vectors Expressing Filovirus Glycoproteins Lack Neurovirulence in Nonhuman Primates

(2012) Chad E. Mire et al.   PLoS Neglected Tropical Diseases

Protective Efficacy of a Bivalent Recombinant Vesicular Stomatitis Virus Vaccine in the Syrian Hamster Model of Lethal Ebola Virus Infection

(2011) Yoshimi Tsuda et al.   JOURNAL OF INFECTIOUS DISEASES

Single Immunization With a Monovalent Vesicular Stomatitis Virus–Based Vaccine Protects Nonhuman Primates Against Heterologous Challenge With Bundibugyo ebolavirus

(2011) Darryl Falzarano et al.   JOURNAL OF INFECTIOUS DISEASES

Management of Accidental Exposure to Ebola Virus in the Biosafety Level 4 Laboratory, Hamburg, Germany

(2011) Stephan Günther et al.   JOURNAL OF INFECTIOUS DISEASES

Vesicular Stomatitis Virus–Based Ebola Vaccines With Improved Cross-Protective Efficacy

(2011) Andrea Marzi et al.   JOURNAL OF INFECTIOUS DISEASES

Vesicular Stomatitis Virus-Based Vaccine Protects Hamsters against Lethal Challenge with Andes Virus

(2011) K. S. Brown et al.   JOURNAL OF VIROLOGY

Single-Injection Vaccine Protects Nonhuman Primates against Infection with Marburg Virus and Three Species of Ebola Virus

(2009) T. W. Geisbert et al.   JOURNAL OF VIROLOGY

Mucosal Immunization of Cynomolgus Macaques with the VSVΔG/ZEBOVGP Vaccine Stimulates Strong Ebola GP-Specific Immune Responses

(2009) Xiangguo Qiu et al.   PLoS One

Vesicular stomatitis virus-based vaccines protect nonhuman primates against aerosol challenge with Ebola and Marburg viruses

(2008) Thomas W. Geisbert et al.   VACCINE

Vesicular Stomatitis Virus-Based Ebola Vaccine Is Well-Tolerated and Protects Immunocompromised Nonhuman Primates

(2008) Thomas W. Geisbert et al.   PLoS Pathogens