Sex and sex steroids impact influenza pathogenesis across the life course

Production of amphiregulin and recovery from influenza is greater in males than females

(2018) Meghan S. Vermillion et al.   Biology of Sex Differences

Androgen-Induced Immunosuppression

(2018) Melanie R. Gubbels Bupp et al.   Frontiers in Immunology

Sex Hormones Regulate Innate Immune Cells and Promote Sex Differences in Respiratory Virus Infection

(2018) Sapana Kadel et al.   Frontiers in Immunology

Differential Redox State Contributes to Sex Disparities in the Response to Influenza Virus Infection in Male and Female Mice

(2018) Ignacio Celestino et al.   Frontiers in Immunology

Progesterone-Based Contraceptives Reduce Adaptive Immune Responses and Protection against Sequential Influenza A Virus Infections

(2017) Olivia J. Hall et al.   JOURNAL OF VIROLOGY

Interim estimates of influenza vaccine effectiveness in 2012/13 from Canada’s sentinel surveillance network, January 2013

(2017) D M Skowronski et al.   Eurosurveillance

Age and testosterone mediate influenza pathogenesis in male mice

(2016) Landon G. vom Steeg et al.   AMERICAN JOURNAL OF PHYSIOLOGY-LUNG CELLULAR AND MOLECULAR PHYSIOLOGY

SeXX Matters in Infectious Disease Pathogenesis

(2016) Landon G. vom Steeg et al.   PLoS Pathogens

Progesterone-Based Therapy Protects Against Influenza by Promoting Lung Repair and Recovery in Females

(2016) Olivia J. Hall et al.   PLoS Pathogens

Estimating age-specific trends in circulating testosterone and sex hormone-binding globulin in males and females across the lifespan

(2016) David J Handelsman et al.   ANNALS OF CLINICAL BIOCHEMISTRY

Suppressive effects of androgens on the immune system

(2015) Abhishek Trigunaite et al.   CELLULAR IMMUNOLOGY

Narrowing of Human Influenza A Virus-Specific T Cell Receptor α and β Repertoires with Increasing Age

(2015) Anna Gil et al.   JOURNAL OF VIROLOGY

Sex differences in H7N9 influenza A virus pathogenesis

(2015) Julia Hoffmann et al.   VACCINE

Comparison of Patients Hospitalized With Influenza A Subtypes H7N9, H5N1, and 2009 Pandemic H1N1

(2014) Chen Wang et al.   CLINICAL INFECTIOUS DISEASES

Spatio-temporal analysis of pneumonia and influenza hospitalizations in Ontario, Canada

(2014) Eric J. Crighton et al.   Geospatial Health

Biological Differences Between the Sexes and Susceptibility to Tuberculosis

(2014) S. Nhamoyebonde et al.   JOURNAL OF INFECTIOUS DISEASES

17 -Estradiol Protects Females against Influenza by Recruiting Neutrophils and Increasing Virus-Specific CD8 T Cell Responses in the Lungs

(2014) D. P. Robinson et al.   JOURNAL OF VIROLOGY

Age-specific and sex-specific morbidity and mortality from avian influenza A(H7N9)

(2013) Joseph P. Dudley et al.   JOURNAL OF CLINICAL VIROLOGY

Comparative epidemiology of human infections with avian influenza A H7N9 and H5N1 viruses in China: a population-based study of laboratory-confirmed cases

(2013) Benjamin J Cowling et al.   LANCET

Epidemiology of Human Infections with Avian Influenza A(H7N9) Virus in China

(2013) Qun Li et al.   NEW ENGLAND JOURNAL OF MEDICINE

Influenza Virus Specific CD8+T Cells Exacerbate Infection Following High Dose Influenza Challenge of Aged Mice

(2013) E. M. Parzych et al.   Biomed Research International

Sex Differences and Sex Steroids in Lung Health and Disease

(2012) Elizabeth A. Townsend et al.   ENDOCRINE REVIEWS

Aging and Declining Testosterone: Past, Present, and Hopes for the Future

(2012) B. R. Zirkin et al.   JOURNAL OF ANDROLOGY

The Prostanoid 15-Deoxy-Δ12,14-Prostaglandin-J2 Reduces Lung Inflammation and Protects Mice Against Lethal Influenza Infection

(2012) Alexandre Cloutier et al.   JOURNAL OF INFECTIOUS DISEASES

Differential Pathological and Immune Responses in Newly Weaned Ferrets Are Associated with a Mild Clinical Outcome of Pandemic 2009 H1N1 Infection

(2012) S. S. H. Huang et al.   JOURNAL OF VIROLOGY

Estrogen Mediates Innate and Adaptive Immune Alterations to Influenza Infection in Pregnant Mice

(2012) Michael A. Pazos et al.   PLoS One

Neutrophils sustain effective CD8+ T-cell responses in the respiratory tract following influenza infection

(2011) Michelle D Tate et al.   IMMUNOLOGY AND CELL BIOLOGY

Sexual dimorphism in lung function responses to acute influenza A infection

(2011) Alexander N. Larcombe et al.   Influenza and Other Respiratory Viruses

Innate lymphoid cells promote lung-tissue homeostasis after infection with influenza virus

(2011) Laurel A Monticelli et al.   NATURE IMMUNOLOGY

Sex- and Age-Related Differences in Morbidity Rates of 2009 Pandemic Influenza A H1N1 Virus of Swine Origin in Japan

(2011) Nobuoki Eshima et al.   PLoS One

Suppression of cytokine storm with a sphingosine analog provides protection against pathogenic influenza virus

(2011) K. B. Walsh et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Antibody responses and cross protection against lethal influenza A viruses differ between the sexes in C57BL/6 mice

(2011) Maria E. Lorenzo et al.   VACCINE

17β-Estradiol restores antibody responses to an influenza vaccine in a postmenopausal mouse model

(2011) Doan C. Nguyen et al.   VACCINE

Responses of Mouse Airway Epithelial Cells and Alveolar Macrophages to Virulent and Avirulent Strains of Influenza A Virus

(2011) Michelle D. Tate et al.   VIRAL IMMUNOLOGY

Age-related sensitivity and pathological differences in infections by 2009 pandemic influenza A (H1N1) virus

(2011) Shihui Sun et al.   Virology Journal

Sex chromosome complement contributes to sex differences in coxsackievirus B3 but not influenza A virus pathogenesis

(2011) Dionne P Robinson et al.   Biology of Sex Differences

Host response to influenza virus: protection versus immunopathology

(2010) JSM Peiris et al.   CURRENT OPINION IN IMMUNOLOGY

Animal Models for Influenza Virus Pathogenesis and Transmission

(2010) Nicole M. Bouvier et al.   Viruses-Basel

Critically Ill Patients With 2009 Influenza A(H1N1) Infection in Canada

(2009) Anand Kumar   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Neutrophils Ameliorate Lung Injury and the Development of Severe Disease during Influenza Infection

(2009) M. D. Tate et al.   JOURNAL OF IMMUNOLOGY

Limited expansion of virus-specific CD8 T cells in the aged environment

(2009) Jiu Jiang et al.   MECHANISMS OF AGEING AND DEVELOPMENT

Effector T cells control lung inflammation during acute influenza virus infection by producing IL-10

(2009) Jie Sun et al.   NATURE MEDICINE

Testing the influenza–tuberculosis selective mortality hypothesis with Union Army data

(2009) Andrew Noymer   SOCIAL SCIENCE & MEDICINE

Age-associated decline in T cell repertoire diversity leads to holes in the repertoire and impaired immunity to influenza virus

(2008) Eric J. Yager et al.   JOURNAL OF EXPERIMENTAL MEDICINE