Roles of specific aminoglycoside–ribosome interactions in the inhibition of translation

The kinetic mechanism of bacterial ribosome recycling

(2017) Yuanwei Chen et al.   NUCLEIC ACIDS RESEARCH

Accuracy of genetic code translation and its orthogonal corruption by aminoglycosides and Mg2+ ions

(2017) Jingji Zhang et al.   NUCLEIC ACIDS RESEARCH

Intersubunit Bridges of the Bacterial Ribosome

(2016) Qi Liu et al.   JOURNAL OF MOLECULAR BIOLOGY

Multiperspective smFRET reveals rate-determining late intermediates of ribosomal translocation

(2016) Michael R Wasserman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Multiperspective smFRET reveals rate-determining late intermediates of ribosomal translocation

(2016) Michael R Wasserman et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Tobramycin Variants with Enhanced Ribosome-Targeting Activity

(2015) Marina Y. Fosso et al.   CHEMBIOCHEM

Roles of helix H69 of 23S rRNA in translation initiation

(2015) Qi Liu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structure-Based Energetics of mRNA Decoding on the Ribosome

(2014) Priyadarshi Satpati et al.   BIOCHEMISTRY

GTP hydrolysis by EF-G synchronizes tRNA movement on small and large ribosomal subunits

(2014) W. Holtkamp et al.   EMBO JOURNAL

The conserved GTPase LepA contributes mainly to translation initiation in Escherichia coli

(2014) Rohan Balakrishnan et al.   NUCLEIC ACIDS RESEARCH

4′-O-substitutions determine selectivity of aminoglycoside antibiotics

(2014) Déborah Perez-Fernandez et al.   Nature Communications

Structure-Activity Relationships among the Kanamycin Aminoglycosides: Role of Ring I Hydroxyl and Amino Groups

(2012) Sumantha Salian et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Allosteric control of the ribosome by small-molecule antibiotics

(2012) Leyi Wang et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Contribution of intersubunit bridges to the energy barrier of ribosomal translocation

(2012) Qi Liu et al.   NUCLEIC ACIDS RESEARCH

Genetic analysis of new 16S rRNA mutations conferring aminoglycoside resistance in Mycobacterium abscessus

(2011) Rachid Nessar et al.   JOURNAL OF ANTIMICROBIAL CHEMOTHERAPY

Ribosome dynamics and tRNA movement by time-resolved electron cryomicroscopy

(2010) Niels Fischer et al.   NATURE

Correlated conformational events in EF-G and the ribosome regulate translocation

(2010) James B Munro et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ribosomal Translocation: One Step Closer to the Molecular Mechanism

(2009) Shinichiro Shoji et al.   ACS Chemical Biology

Contribution of ribosomal residues to P-site tRNA binding

(2009) Shinichiro Shoji et al.   NUCLEIC ACIDS RESEARCH

Preparation and evaluation of acylated tRNAs

(2008) Sarah E. Walker et al.   METHODS

Role of hybrid tRNA-binding states in ribosomal translocation

(2008) S. E. Walker et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Structural basis for hygromycin B inhibition of protein biosynthesis

(2008) M. A. Borovinskaya et al.   RNA

A role for the 30S subunit E site in maintenance of the translational reading frame

(2008) A. Devaraj et al.   RNA