Catalytic mechanism of DNA polymerases-Two metal ions or three?

Kinetic Mechanism of DNA Polymerases: Contributions of Conformational Dynamics and a Third Divalent Metal Ion

(2018) Austin T. Raper et al.   CHEMICAL REVIEWS

Cation trafficking propels RNA hydrolysis

(2018) Nadine L. Samara et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Time-Dependent Extension from an 8-Oxoguanine Lesion by Human DNA Polymerase Beta

(2017) Andrew J. Reed et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Capturing a mammalian DNA polymerase extending from an oxidized nucleotide

(2017) Amy M. Whitaker et al.   NUCLEIC ACIDS RESEARCH

Determination of chemical identity and occupancy from experimental density maps

(2017) Jimin Wang   PROTEIN SCIENCE

Time-lapse crystallography snapshots of a double-strand break repair polymerase in action

(2017) Joonas A. Jamsen et al.   Nature Communications

How DNA polymerases catalyse replication and repair with contrasting fidelity

(2017) Wen-Jin Wu et al.   Nature Reviews Chemistry

Structural Insights into the Post-Chemistry Steps of Nucleotide Incorporation Catalyzed by a DNA Polymerase

(2016) Andrew J. Reed et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Capture of a third Mg2+ is essential for catalyzing DNA synthesis

(2016) Y. Gao et al.   SCIENCE

A new paradigm of DNA synthesis: three-metal-ion catalysis

(2016) Wei Yang et al.   Cell and Bioscience

Viewing Human DNA Polymerase β Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography

(2015) Rajan Vyas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

Requirement for transient metal ions revealed through computational analysis for DNA polymerase going in reverse

(2015) Lalith Perera et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uncovering the polymerase-induced cytotoxicity of an oxidized nucleotide

(2014) Bret D. Freudenthal et al.   NATURE

Observing a DNA Polymerase Choose Right from Wrong

(2013) Bret D. Freudenthal et al.   CELL

Watching DNA polymerase η make a phosphodiester bond

(2012) Teruya Nakamura et al.   NATURE