Capture of a third Mg2+ is essential for catalyzing DNA synthesis

Roles of Residues Arg-61 and Gln-38 of Human DNA Polymerase η in Bypass of Deoxyguanosine and 7,8-Dihydro-8-oxo-2′-deoxyguanosine

(2015) Yan Su et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Viewing Human DNA Polymerase β Faithfully and Unfaithfully Bypass an Oxidative Lesion by Time-Dependent Crystallography

(2015) Rajan Vyas et al.   JOURNAL OF THE AMERICAN CHEMICAL SOCIETY

How DNA Polymerases Catalyze DNA Replication, Repair, and Mutation

(2014) Ming-Daw Tsai   BIOCHEMISTRY

Observing a DNA Polymerase Choose Right from Wrong

(2013) Bret D. Freudenthal et al.   CELL

Advances in the development of nucleoside and nucleotide analogues for cancer and viral diseases

(2013) Lars Petter Jordheim et al.   NATURE REVIEWS DRUG DISCOVERY

Watching DNA polymerase η make a phosphodiester bond

(2012) Teruya Nakamura et al.   NATURE

Structural and Binding Analysis of Pyrimidinol Carboxylic Acid andN-Hydroxy Quinazolinedione HIV-1 RNase H Inhibitors

(2011) Eric B. Lansdon et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

The Structure of a High Fidelity DNA Polymerase Bound to a Mismatched Nucleotide Reveals an “Ajar” Intermediate Conformation in the Nucleotide Selection Mechanism

(2011) Eugene Y. Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

XDS

(2010) Wolfgang Kabsch   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Features and development ofCoot

(2010) P. Emsley et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

PHENIX: a comprehensive Python-based system for macromolecular structure solution

(2010) Paul D. Adams et al.   ACTA CRYSTALLOGRAPHICA SECTION D-BIOLOGICAL CRYSTALLOGRAPHY

Structure and mechanism of human DNA polymerase η

(2010) Christian Biertümpfel et al.   NATURE

Structural Insight into Translesion Synthesis by DNA Pol II

(2009) Feng Wang et al.   CELL

DNA Polymerase β Substrate Specificity

(2009) William A. Beard et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Role of Induced Fit in Enzyme Specificity: A Molecular Forward/Reverse Switch

(2008) Kenneth A. Johnson   JOURNAL OF BIOLOGICAL CHEMISTRY

Kemp elimination catalysts by computational enzyme design

(2008) Daniela Röthlisberger et al.   NATURE

Structure of PolC reveals unique DNA binding and fidelity determinants

(2008) R. J. Evans et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

De Novo Computational Design of Retro-Aldol Enzymes

(2008) L. Jiang et al.   SCIENCE