Mcm10 has potent strand-annealing activity and limits translocase-mediated fork regression

The mechanism of eukaryotic CMG helicase activation

(2018) Max E. Douglas et al.   NATURE

RPA and RAD51: fork reversal, fork protection, and genome stability

(2018) Kamakoti P. Bhat et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

RPA and RAD51: fork reversal, fork protection, and genome stability

(2018) Kamakoti P. Bhat et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Mcm10 regulates DNA replication elongation by stimulating the CMG replicative helicase

(2017) Marko Lõoke et al.   GENES & DEVELOPMENT

How the Eukaryotic Replisome Achieves Rapid and Efficient DNA Replication

(2017) Joseph T.P. Yeeles et al.   MOLECULAR CELL

Structure of eukaryotic CMG helicase at a replication fork and implications to replisome architecture and origin initiation

(2017) Roxana Georgescu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Chromosome Duplication in Saccharomyces cerevisiae

(2016) S. P. Bell et al.   GENETICS

Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation

(2016) Zuanning Yuan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Strand displacement synthesis by yeast DNA polymerase ε

(2016) Rais A. Ganai et al.   NUCLEIC ACIDS RESEARCH

Cryo-EM structures of the eukaryotic replicative helicase bound to a translocation substrate

(2016) Ferdos Abid Ali et al.   Nature Communications

Structure of the eukaryotic replicative CMG helicase suggests a pumpjack motion for translocation

(2016) Zuanning Yuan et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Recruitment of Mcm10 to Sites of Replication Initiation Requires Direct Binding to the Minichromosome Maintenance (MCM) Complex

(2015) Max E. Douglas et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

A Major Role of DNA Polymerase δ in Replication of Both the Leading and Lagging DNA Strands

(2015) Robert E. Johnson et al.   MOLECULAR CELL

Reconstitution of a eukaryotic replisome reveals suppression mechanisms that define leading/lagging strand operation

(2015) Roxana E Georgescu et al.   eLife

The N-terminus of Mcm10 is important for interaction with the 9-1-1 clamp and in resistance to DNA damage

(2014) Robert C. Alver et al.   NUCLEIC ACIDS RESEARCH

MCM10: One tool for all—Integrity, maintenance and damage control

(2014) Yee Mon Thu et al.   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Mcm10 Self-Association Is Mediated by an N-Terminal Coiled-Coil Domain

(2013) Wenyue Du et al.   PLoS One

Principles and Concepts of DNA Replication in Bacteria, Archaea, and Eukarya

(2013) M. O'Donnell et al.   Cold Spring Harbor Perspectives in Biology

Substrate-Selective Repair and Restart of Replication Forks by DNA Translocases

(2013) Rémy Bétous et al.   Cell Reports

Mcm10 Plays a Role in Functioning of the Eukaryotic Replicative DNA Helicase, Cdc45-Mcm-GINS

(2012) George Watase et al.   CURRENT BIOLOGY

Mcm10 plays an essential role in origin DNA unwinding after loading of the CMG components

(2012) Mai Kanke et al.   EMBO JOURNAL

Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation

(2012) Frederick van Deursen et al.   EMBO JOURNAL

Properties of the human Cdc45/Mcm2-7/GINS helicase complex and its action with DNA polymerase   in rolling circle DNA synthesis

(2012) Y.-H. Kang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Eukaryotic Origin-Dependent DNA Replication In Vitro Reveals Sequential Action of DDK and S-CDK Kinases

(2011) Ryan C. Heller et al.   CELL

Xenopus DNA2 is a helicase/nuclease that is found in complexes with replication proteins And-1/Ctf4 and Mcm10 and DSB response proteins Nbs1 and ATM

(2010) Karen E. Wawrousek et al.   CELL CYCLE

Physical Interactions between Mcm10, DNA, and DNA Polymerase α

(2009) Eric M. Warren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for DNA Binding by Replication Initiator Mcm10

(2008) Eric M. Warren et al.   STRUCTURE

Knockdown of human MCM10 exhibits delayed and incomplete chromosome replication

(2007) Jong Hoon Park et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS