Mcm10 associates with the loaded DNA helicase at replication origins and defines a novel step in its activation

Targeted disruption of Mcm10 causes defective embryonic cell proliferation and early embryo lethality

(2011) Han Jeong Lim et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Eukaryotic Origin-Dependent DNA Replication In Vitro Reveals Sequential Action of DDK and S-CDK Kinases

(2011) Ryan C. Heller et al.   CELL

Selective Bypass of a Lagging Strand Roadblock by the Eukaryotic Replicative DNA Helicase

(2011) Yu V. Fu et al.   CELL

Mcm10 interacts with Rad4/Cut5TopBP1 and its association with origins of DNA replication is dependent on Rad4/Cut5TopBP1

(2011) Mark Taylor et al.   DNA REPAIR

The effect of the intra-S-phase checkpoint on origins of replication in human cells

(2011) Neerja Karnani et al.   GENES & DEVELOPMENT

MCM2-7 Form Double Hexamers at Licensed Origins inXenopusEgg Extract

(2011) Agnieszka Gambus et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

The structural basis for MCM2–7 helicase activation by GINS and Cdc45

(2011) Alessandro Costa et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Ctf4p facilitates Mcm10p to promote DNA replication in budding yeast

(2010) Jiafeng Wang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

SnapShot: The Replisome

(2010) Nina Y. Yao et al.   CELL

Cyclin-dependent kinase-dependent initiation of chromosomal DNA replication

(2010) Hiroyuki Araki   CURRENT OPINION IN CELL BIOLOGY

CDK-dependent complex formation between replication proteins Dpb11, Sld2, Pol  , and GINS in budding yeast

(2010) S. Muramatsu et al.   GENES & DEVELOPMENT

How do Cdc7 and cyclin-dependent kinases trigger the initiation of chromosome replication in eukaryotic cells?

(2010) K. Labib   GENES & DEVELOPMENT

Multiple Functions for Drosophila Mcm10 Suggested Through Analysis of Two Mcm10 Mutant Alleles

(2010) J. Apger et al.   GENETICS

Uncoupling of Sister Replisomes during Eukaryotic DNA Replication

(2010) Hasan Yardimci et al.   MOLECULAR CELL

Activation of the MCM2-7 Helicase by Association with Cdc45 and GINS Proteins

(2010) Ivar Ilves et al.   MOLECULAR CELL

Ancient diversification of eukaryotic MCM DNA replication proteins

(2009) Yuan Liu et al.   BMC EVOLUTIONARY BIOLOGY

Concerted Loading of Mcm2–7 Double Hexamers around DNA during DNA Replication Origin Licensing

(2009) Dirk Remus et al.   CELL

The Amino-Terminal TPR Domain of Dia2 Tethers SCFDia2 to the Replisome Progression Complex

(2009) Hiroko Morohashi et al.   CURRENT BIOLOGY

Eukaryotic DNA replication control: Lock and load, then fire

(2009) Dirk Remus et al.   CURRENT OPINION IN CELL BIOLOGY

A key role for Ctf4 in coupling the MCM2-7 helicase to DNA polymerase α within the eukaryotic replisome

(2009) Agnieszka Gambus et al.   EMBO JOURNAL

Novel DNA Binding Properties of the Mcm10 Protein from Saccharomyces cerevisiae

(2009) Shlomo Eisenberg et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Physical Interactions between Mcm10, DNA, and DNA Polymerase α

(2009) Eric M. Warren et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Alternative Mechanisms for Coordinating Polymerase   and MCM Helicase

(2009) C. Lee et al.   MOLECULAR AND CELLULAR BIOLOGY

A double-hexameric MCM2-7 complex is loaded onto origin DNA during licensing of eukaryotic DNA replication

(2009) C. Evrin et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Mcm10 Mediates the Interaction Between DNA Replication and Silencing Machineries

(2008) I. Liachko et al.   GENETICS

Structural Basis for DNA Binding by Replication Initiator Mcm10

(2008) Eric M. Warren et al.   STRUCTURE