Structural and mechanistic insights into the function of the unconventional class XIV myosin MyoA fromToxoplasma gondii

High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing

(2018) Ahmet Mentes et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Dissecting the molecular assembly of theToxoplasma gondiiMyoA motility complex

(2017) Cameron J. Powell et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Reconstitution of the core of the malaria parasite glideosome with recombinantPlasmodiumclass XIV myosin A andPlasmodiumactin

(2017) Carol S. Bookwalter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Omecamtiv Mecarbil Enhances the Duty Ratio of Human β-Cardiac Myosin Resulting in Increased Calcium Sensitivity and Slowed Force Development in Cardiac Muscle

(2017) Anja M. Swenson et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Gliding motility powers invasion and egress in Apicomplexa

(2017) Karine Frénal et al.   NATURE REVIEWS MICROBIOLOGY

An Apicomplexan Actin-Binding Protein Serves as a Connector and Lipid Sensor to Coordinate Motility and Invasion

(2016) Damien Jacot et al.   Cell Host & Microbe

The apicomplexan glideosome and adhesins – Structures and function

(2015) Lauren E. Boucher et al.   JOURNAL OF STRUCTURAL BIOLOGY

Toxoplasma gondiidissemination: a parasite's journey through the infected host

(2015) K. S. Harker et al.   PARASITE IMMUNOLOGY

Gliding motility in apicomplexan parasites

(2015) Matthew B. Heintzelman   SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY

Phosphorylation of a Myosin Motor by TgCDPK3 Facilitates Rapid Initiation of Motility during Toxoplasma gondii egress

(2015) Rajshekhar Y. Gaji et al.   PLoS Pathogens

AToxoplasma gondiiClass XIV Myosin, Expressed inSf9 Cells with a Parasite Co-chaperone, Requires Two Light Chains for Fast Motility

(2014) Carol S. Bookwalter et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Crystal Structure of Human Myosin 1c—The Motor in GLUT4 Exocytosis: Implications for Ca2+ Regulation and 14-3-3 Binding

(2014) Stefan Münnich et al.   JOURNAL OF MOLECULAR BIOLOGY

Calcium-dependent phosphorylation alters class XIVa myosin function in the protozoan parasite Toxoplasma gondii

(2014) Qing Tang et al.   MOLECULAR BIOLOGY OF THE CELL

The Toxoplasma Acto-MyoA Motor Complex Is Important but Not Essential for Gliding Motility and Host Cell Invasion

(2014) Saskia Egarter et al.   PLoS One

A vertebrate myosin-I structure reveals unique insights into myosin mechanochemical tuning

(2014) Henry Shuman et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Plasticity between MyoC- and MyoA-Glideosomes: An Example of Functional Compensation in Toxoplasma gondii Invasion

(2014) Karine Frénal et al.   PLoS Pathogens

Conditional genome engineering in Toxoplasma gondii uncovers alternative invasion mechanisms

(2012) Nicole Andenmatten et al.   NATURE METHODS

Mechanism and Specificity of Pentachloropseudilin-mediated Inhibition of Myosin Motor Activity

(2011) Krishna Chinthalapudi et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Basis for the Allosteric Interference of Myosin Function by Reactive Thiol Region Mutations G680A and G680V

(2011) Matthias Preller et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Inhibition of Myosin ATPase Activity by Halogenated Pseudilins: A Structure–Activity Study

(2011) Matthias Preller et al.   JOURNAL OF MEDICINAL CHEMISTRY

Evolutionarily Divergent, Unstable Filamentous Actin Is Essential for Gliding Motility in Apicomplexan Parasites

(2011) Kristen M. Skillman et al.   PLoS Pathogens

Functional Dissection of the Apicomplexan Glideosome Molecular Architecture

(2010) Karine Frénal et al.   Cell Host & Microbe

Dali server: conservation mapping in 3D

(2010) Liisa Holm et al.   NUCLEIC ACIDS RESEARCH