In silico repositioning of approved drugs against Schistosoma mansoni energy metabolism targets

Effects of a novel SDHI fungicide pyraziflumid on the biology of the plant pathogenic fungi Bipolaris maydis

(2018) Yi-Ping Hou et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Baseline sensitivity of Bipolaris maydis to the novel succinate dehydrogenase inhibitor benzovindiflupyr and its efficacy

(2018) Yi-Ping Hou et al.   PESTICIDE BIOCHEMISTRY AND PHYSIOLOGY

Discovery of Novel Succinate Dehydrogenase Inhibitors by the Integration of in Silico Library Design and Pharmacophore Mapping

(2017) Ting-Ting Yao et al.   JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY

Design, synthesis and biological evaluation of novel nicotinamide derivatives bearing a substituted pyrazole moiety as potential SDH inhibitors

(2017) Xian-Hai Lv et al.   PEST MANAGEMENT SCIENCE

What is the mechanism of action of praziquantel and how might resistance strike?

(2015) Pauline M Cupit et al.   Future Medicinal Chemistry

Therapeutic target database update 2016: enriched resource for bench to clinical drug target and targeted pathway information

(2015) Hong Yang et al.   NUCLEIC ACIDS RESEARCH

PubChem Substance and Compound databases

(2015) Sunghwan Kim et al.   NUCLEIC ACIDS RESEARCH

Activity Profile of an FDA-Approved Compound Library against Schistosoma mansoni

(2015) Gordana Panic et al.   PLoS Neglected Tropical Diseases

Single nucleotide polymorphism at alcohol dehydrogenase-1B is associated with risk of esophageal squamous cell carcinoma

(2014) Bo Ye et al.   Cancer Cell International

Antischistosomal activity of a calcium channel antagonist on schistosomula and adult Schistosoma mansoni worms

(2014) Vanessa Silva-Moraes et al.   MEMORIAS DO INSTITUTO OSWALDO CRUZ

Repurposing drugs for the treatment and control of helminth infections

(2014) Gordana Panic et al.   International Journal for Parasitology-Drugs and Drug Resistance

Drug repurposing and human parasitic protozoan diseases

(2014) Katherine T. Andrews et al.   International Journal for Parasitology-Drugs and Drug Resistance

Drug repositioning by structure-based virtual screening

(2013) Dik-Lung Ma et al.   CHEMICAL SOCIETY REVIEWS

DrugBank 4.0: shedding new light on drug metabolism

(2013) Vivian Law et al.   NUCLEIC ACIDS RESEARCH

New approaches for understanding mechanisms of drug resistance in schistosomes

(2013) ROBERT M. GREENBERG   PARASITOLOGY

A Systematic In Silico Search for Target Similarity Identifies Several Approved Drugs with Potential Activity against the Plasmodium falciparum Apicoplast

(2013) Nadlla Alves Bispo et al.   PLoS One

A Systematic Review of Ethanol and Fomepizole Use in Toxic Alcohol Ingestions

(2013) Lorri Beatty et al.   Emergency Medicine International

Rational drug repositioning guided by an integrated pharmacological network of protein, disease and drug

(2012) Hee Lee et al.   BMC Systems Biology

In silico drug repositioning – what we need to know

(2012) Zhichao Liu et al.   DRUG DISCOVERY TODAY

Complex I and ATP synthase mediate membrane depolarization and matrix acidification by isoflurane in mitochondria

(2012) Danijel Pravdic et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

Mefloquine interferes with glycolysis in schistosomula of Schistosoma mansoni via inhibition of enolase

(2012) THERESIA MANNECK et al.   PARASITOLOGY

In silico repositioning of approved drugs for rare and neglected diseases

(2011) Sean Ekins et al.   DRUG DISCOVERY TODAY

Identification of the Schistosoma mansoni Molecular Target for the Antimalarial Drug Artemether

(2011) Rosalba Lepore et al.   Journal of Chemical Information and Modeling

Drug repositioning: Re-investigating existing drugs for new therapeutic indications

(2011) BM Padhy et al.   Journal of Postgraduate Medicine

GeneDB--an annotation database for pathogens

(2011) F. J. Logan-Klumpler et al.   NUCLEIC ACIDS RESEARCH

Schistosoma mansoni express higher levels of multidrug resistance-associated protein 1 (SmMRP1) in juvenile worms and in response to praziquantel

(2010) Ravi S. Kasinathan et al.   MOLECULAR AND BIOCHEMICAL PARASITOLOGY

PROMISCUOUS: a database for network-based drug-repositioning

(2010) J. von Eichborn et al.   NUCLEIC ACIDS RESEARCH

Identification of Attractive Drug Targets in Neglected-Disease Pathogens Using an In Silico Approach

(2010) Gregory J. Crowther et al.   PLoS Neglected Tropical Diseases

Praziquantel: mechanisms of action, resistance and new derivatives for schistosomiasis

(2008) Michael J Doenhoff et al.   CURRENT OPINION IN INFECTIOUS DISEASES