The autophagy inhibitor spautin-1, either alone or combined with doxorubicin, decreases cell survival and colony formation in canine appendicular osteosarcoma cells

Autophagy inhibitors suppress environmental particulate matter-induced airway inflammation

(2017) Xu-Chen Xu et al.   TOXICOLOGY LETTERS

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Immunotherapy with a HER2-Targeting Listeria Induces HER2-Specific Immunity and Demonstrates Potential Therapeutic Effects in a Phase I Trial in Canine Osteosarcoma

(2016) N. J. Mason et al.   CLINICAL CANCER RESEARCH

Calreticulin-mutant proteins induce megakaryocytic signaling to transform hematopoietic cells and undergo accelerated degradation and Golgi-mediated secretion

(2016) Lijuan Han et al.   Journal of Hematology & Oncology

Canine Osteosarcoma Treated by Post-Amputation Sequential Accelerated Doxorubicin and Carboplatin Chemotherapy: 38 Cases

(2016) Angela E. Frimberger et al.   JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION

Resveratrol inhibits IL-6-induced ovarian cancer cell migration through epigenetic up-regulation of autophagy

(2016) Alessandra Ferraresi et al.   MOLECULAR CARCINOGENESIS

Spautin-1 Ameliorates Acute Pancreatitis via Inhibiting Impaired Autophagy and Alleviating Calcium Overload

(2016) Juan Xiao et al.   MOLECULAR MEDICINE

EGFR-targeted mAb therapy modulates autophagy in head and neck squamous cell carcinoma through NLRX1–TUFM protein complex

(2016) Y Lei et al.   ONCOGENE

17-AAG and Apoptosis, Autophagy, and Mitophagy in Canine Osteosarcoma Cell Lines

(2016) M. Massimini et al.   VETERINARY PATHOLOGY

Autophagy positively regulates DNA damage recognition by nucleotide excision repair

(2015) Lei Qiang et al.   Autophagy

Autophagy inhibition re-sensitizes pulse stimulation-selected paclitaxel-resistant triple negative breast cancer cells to chemotherapy-induced apoptosis

(2015) Jian Wen et al.   BREAST CANCER RESEARCH AND TREATMENT

CD40 ligand exhibits a direct antiviral effect on Herpes Simplex Virus type-1 infection via a PI3K-dependent, autophagy-independent mechanism

(2015) Virginia-Maria Vlahava et al.   CELLULAR SIGNALLING

Autophagic flux inhibition and lysosomogenesis ensuing cellular capture and retention of the cationic drug quinacrine in murine models

(2015) Alexandre Parks et al.   PeerJ

Impact of Toceranib/Piroxicam/Cyclophosphamide Maintenance Therapy on Outcome of Dogs with Appendicular Osteosarcoma following Amputation and Carboplatin Chemotherapy: A Multi-Institutional Study

(2015) Cheryl A. London et al.   PLoS One

Phase I clinical trial and pharmacodynamic evaluation of combination hydroxychloroquine and doxorubicin treatment in pet dogs treated for spontaneously occurring lymphoma

(2014) Rebecca A Barnard et al.   Autophagy

Combination of AKT inhibition with autophagy blockade effectively reduces ascites-derived ovarian cancer cell viability

(2014) Rohann J.M. Correa et al.   CARCINOGENESIS

Recent advances in osteosarcoma

(2014) Sander M Botter et al.   CURRENT OPINION IN PHARMACOLOGY

The combination of irreversible EGFR TKIs and SAHA induces apoptosis and autophagy-mediated cell death to overcome acquired resistance in EGFRT790M-mutated lung cancer

(2014) Tae-Gul Lee et al.   INTERNATIONAL JOURNAL OF CANCER

Spautin-1, a novel autophagy inhibitor, enhances imatinib-induced apoptosis in chronic myeloid leukemia

(2014) SHAN SHAO et al.   INTERNATIONAL JOURNAL OF ONCOLOGY

Use of Single-Agent Carboplatin as Adjuvant or Neoadjuvant Therapy in Conjunction With Amputation for Appendicular Osteosarcoma in Dogs

(2014) Brenda Phillips et al.   JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION

Comparison of Carboplatin and Doxorubicin-Based Chemotherapy Protocols in 470 Dogs after Amputation for Treatment of Appendicular Osteosarcoma

(2014) L.E. Selmic et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Targeting SQSTM1/p62 Induces Cargo Loading Failure and Converts Autophagy to Apoptosis via NBK/Bik

(2014) S. Chen et al.   MOLECULAR AND CELLULAR BIOLOGY

Autophagy prevents doxorubicin-induced apoptosis in osteosarcoma

(2014) DONGXU ZHAO et al.   Molecular Medicine Reports

PDGF-mediated autophagy regulates vascular smooth muscle cell phenotype and resistance to oxidative stress

(2013) Joshua K. Salabei et al.   BIOCHEMICAL JOURNAL

Chaperone-mediated autophagy degrades mutant p53

(2013) H. Vakifahmetoglu-Norberg et al.   GENES & DEVELOPMENT

Pharmacokinetic study and evaluation of the safety of taurolidine for dogs with osteosarcoma

(2013) Kevin Marley et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Postoperative Adjuvant Combination Therapy with Doxorubicin and Noncytotoxic Suramin in Dogs with Appendicular Osteosarcoma

(2013) Francisco J. Alvarez et al.   JOURNAL OF THE AMERICAN ANIMAL HOSPITAL ASSOCIATION

A case study of personalized therapy for osteosarcoma

(2013) Lara E. Davis et al.   PEDIATRIC BLOOD & CANCER

Prognostic factors of early metastasis and mortality in dogs with appendicular osteosarcoma after receiving surgery: An individual patient data meta-analysis

(2013) A.F. Schmidt et al.   PREVENTIVE VETERINARY MEDICINE

Adjuvant therapy with carboplatin and pamidronate for canine appendicular osteosarcoma

(2013) A. R. Kozicki et al.   Veterinary and Comparative Oncology

Carboplatin versus alternating carboplatin and doxorubicin for the adjuvant treatment of canine appendicular osteosarcoma: a randomized, phase III trial

(2013) K. A. Skorupski et al.   Veterinary and Comparative Oncology

Toxicity and efficacy of a novel doxorubicin and carboplatin chemotherapy protocol for the treatment of canine appendicular osteosarcoma following limb amputation

(2012) AE Lane et al.   AUSTRALIAN VETERINARY JOURNAL

Autophagy in tumorigenesis and cancer therapy: Dr. Jekyll or Mr. Hyde?

(2012) Shengtao Zhou et al.   CANCER LETTERS

The products of the reaction between 6-amine-1,3-dimethyl uracil and bis-chalcones induce cytotoxicity with massive vacuolation in HeLa cervical cancer cell line

(2012) José D. Solano et al.   EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY

Autophagy and cancer

(2012) Kyeong Sook Choi   EXPERIMENTAL AND MOLECULAR MEDICINE

Beclin1 Controls the Levels of p53 by Regulating the Deubiquitination Activity of USP10 and USP13

(2011) Junli Liu et al.   CELL

Hallmarks of Cancer: The Next Generation

(2011) Douglas Hanahan et al.   CELL

The dynamic nature of autophagy in cancer

(2011) A. C. Kimmelman   GENES & DEVELOPMENT

Adjuvant Carboplatin and Gemcitabine Combination Chemotherapy Postamputation in Canine Appendicular Osteosarcoma

(2011) M. McMahon et al.   JOURNAL OF VETERINARY INTERNAL MEDICINE

Preliminary evidence for biologic activity of toceranib phosphate (Palladia®) in solid tumours

(2011) C. London et al.   Veterinary and Comparative Oncology

Rapamycin Pharmacokinetic and Pharmacodynamic Relationships in Osteosarcoma: A Comparative Oncology Study in Dogs

(2010) Melissa C. Paoloni et al.   PLoS One

The Double-Edged Sword of Autophagy Modulation in Cancer

(2009) E. White et al.   CLINICAL CANCER RESEARCH

Simultaneous Inference in General Parametric Models

(2008) Torsten Hothorn et al.   BIOMETRICAL JOURNAL

Standardized high-throughput evaluation of cell-based compound screens

(2008) Peter Frommolt et al.   BMC BIOINFORMATICS

Use of alternating administration of carboplatin and doxorubicin in dogs with microscopic metastases after amputation for appendicular osteosarcoma: 50 cases (1999–2006)

(2008) Nicholas J. Bacon et al.   JAVMA-JOURNAL OF THE AMERICAN VETERINARY MEDICAL ASSOCIATION