Proanthocyanidins Antagonize Arsenic-Induced Oxidative Damage and Promote Arsenic Methylation through Activation of the Nrf2 Signaling Pathway

The PKCδ-Nrf2-ARE signalling pathway may be involved in oxidative stress in arsenic-induced liver damage in rats

(2018) Yong Hu et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Protective Mechanism of Sulforaphane on Cadmium-Induced Sertoli Cell Injury in Mice Testis via Nrf2/ARE Signaling Pathway

(2018) Shu-Hua Yang et al.   MOLECULES

L-Ascorbic Acid and α-Tocopherol Reduces Hepatotoxicity Associated with Arsenic Trioxide Chemotherapy by Modulating Nrf2 and Bcl2 Transcription Factors in Chang liver Cells

(2018) Radhakrishnan Chandraprabha Vineetha et al.   NUTRITION AND CANCER-AN INTERNATIONAL JOURNAL

Carnosic Acid, a Natural Diterpene, Attenuates Arsenic-Induced Hepatotoxicity via Reducing Oxidative Stress, MAPK Activation, and Apoptotic Cell Death Pathway

(2018) Sonjit Das et al.   Oxidative Medicine and Cellular Longevity

Continued 26S proteasome dysfunction in mouse brain cortical neurons impairs autophagy and the Keap1-Nrf2 oxidative defence pathway

(2017) Aslihan Ugun-Klusek et al.   Cell Death & Disease

GSPE reduces lead-induced oxidative stress by activating the Nrf2 pathway and suppressing miR153 and GSK-3β in rat kidney

(2017) Biying Liu et al.   Oncotarget

Small Molecule Inhibitor of NRF2 Selectively Intervenes Therapeutic Resistance in KEAP1-Deficient NSCLC Tumors

(2016) Anju Singh et al.   ACS Chemical Biology

Oxidative Damage Induced by Arsenic in Mice or Rats: A Systematic Review and Meta-Analysis

(2016) Mengchuan Xu et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Antioxidative and prooxidative effects in food lipids and synergism with α-tocopherol of açaí seed extracts and grape rachis extracts

(2016) Priscilla Siqueira Melo et al.   FOOD CHEMISTRY

The Protective Effect of Grape-Seed Proanthocyanidin Extract on Oxidative Damage Induced by Zearalenone in Kunming Mice Liver

(2016) Miao Long et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Proanthocyanidins Attenuation of Chronic Lead-Induced Liver Oxidative Damage in Kunming Mice via the Nrf2/ARE Pathway

(2016) Miao Long et al.   Nutrients

Chronic Arsenic Poisoning Probably Caused by Arsenic-Based Pesticides: Findings from an Investigation Study of a Household

(2016) Yongfang Li et al.   International Journal of Environmental Research and Public Health

Factors Affecting Arsenic Methylation in Arsenic-Exposed Humans: A Systematic Review and Meta-Analysis

(2016) Hui Shen et al.   International Journal of Environmental Research and Public Health

The Keap1/Nrf2 pathway in health and disease: from the bench to the clinic

(2015) Maria A. O’Connell et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Protective Effects of Combined Selenium and Punica granatum Treatment on Some Inflammatory and Oxidative Stress Markers in Arsenic-Induced Hepatotoxicity in Rats

(2015) Noha M. Shafik et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Lutein alleviates arsenic-induced reproductive toxicity in male mice via Nrf2 signaling

(2015) SG Li et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

Efficacy of Procyanidins against In Vivo Cellular Oxidative Damage: A Systematic Review and Meta-Analysis

(2015) Shugang Li et al.   PLoS One

Tert-Butylhydroquinone as a Phenolic Activator of Nrf2 Antagonizes Arsenic-Induced Oxidative Cytotoxicity but Promotes Arsenic Methylation and Detoxication in Human Hepatocyte Cell Line

(2014) Xiaoxu Duan et al.   BIOLOGICAL TRACE ELEMENT RESEARCH

Arsenic trioxide induces oxidative stress, DNA damage, and mitochondrial pathway of apoptosis in human leukemia (HL-60) cells

(2014) Sanjay Kumar et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

Antioxidant Properties of Proanthocyanidins Attenuate Carbon Tetrachloride (CCl4)–Induced Steatosis and Liver Injury in Rats via CYP2E1 Regulation

(2014) Ning Dai et al.   JOURNAL OF MEDICINAL FOOD

Immunomodulatory role of Emblica officinalis in arsenic induced oxidative damage and apoptosis in thymocytes of mice

(2013) Manish K Singh et al.   BMC Complementary and Alternative Medicine

Association of urinary monomethylated arsenic concentration and risk of hypertension: a cross-sectional study from arsenic contaminated areas in northwestern China

(2013) Xin Li et al.   Environmental Health

Curcumin attenuates arsenic-induced hepatic injuries and oxidative stress in experimental mice through activation of Nrf2 pathway, promotion of arsenic methylation and urinary excretion

(2013) Shuang Gao et al.   FOOD AND CHEMICAL TOXICOLOGY

Black soybean seed coat polyphenols prevent B(a)P-induced DNA damage through modulating drug-metabolizing enzymes in HepG2 cells and ICR mice

(2013) Tianshun Zhang et al.   MUTATION RESEARCH-GENETIC TOXICOLOGY AND ENVIRONMENTAL MUTAGENESIS

Rapid Equilibrium Kinetic Analysis of Arsenite Methylation Catalyzed by Recombinant Human Arsenic (+3 Oxidation State) Methyltransferase (hAS3MT)

(2012) Shuping Wang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Interspecies differences in metabolism of arsenic by cultured primary hepatocytes

(2010) Zuzana Drobná et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Arsenic trioxide induces the apoptosis in vascular smooth muscle cells via increasing intracellular calcium and ROS formation

(2009) Jing-Xiu Li et al.   MOLECULAR BIOLOGY REPORTS