Hsp90ab1 stabilizes LRP5 to promote epithelial–mesenchymal transition via activating of AKT and Wnt/β-catenin signaling pathways in gastric cancer progression

3′-epi-12β-hydroxyfroside, a new cardenolide, induces cytoprotective autophagy via blocking the Hsp90/Akt/mTOR axis in lung cancer cells

(2018) Yan Sun et al.   Theranostics

TP53TG1 enhances cisplatin sensitivity of non-small cell lung cancer cells through regulating miR-18a/PTEN axis

(2018) Huijuan Xiao et al.   Cell and Bioscience

Clinical significance of altering epithelial–mesenchymal transition in metastatic lymph nodes of gastric cancer

(2017) Keishi Okubo et al.   Gastric Cancer

Wnt5a promotes Frizzled-4 signalosome assembly by stabilizing cysteine-rich domain dimerization

(2017) Zachary J. DeBruine et al.   GENES & DEVELOPMENT

Down-regulation of DAB2IP promotes colorectal cancer invasion and metastasis by translocating hnRNPK into nucleus to enhance the transcription of MMP2

(2017) X.H. Zhu et al.   INTERNATIONAL JOURNAL OF CANCER

Role of RBP2-Induced ER and IGF1R-ErbB Signaling in Tamoxifen Resistance in Breast Cancer

(2017) Hee-Joo Choi et al.   JNCI-Journal of the National Cancer Institute

Cytoplasmic translocation of MTA1 coregulator promotes de-repression of SGK1 transcription in hypoxic cancer cells

(2017) H Marzook et al.   ONCOGENE

Downregulation of miR-218 contributes to epithelial–mesenchymal transition and tumor metastasis in lung cancer by targeting Slug/ZEB2 signaling

(2017) Z-M Shi et al.   ONCOGENE

Role of RBP2-Induced ER and IGF1R-ErbB Signaling in Tamoxifen Resistance in Breast Cancer

(2017) Hee-Joo Choi et al.   JNCI-Journal of the National Cancer Institute

Proteasome inhibitor-induced cleavage of HSP90 is mediated by ROS generation and caspase 10-activation in human leukemic cells

(2017) Sangkyu Park et al.   Redox Biology

Inhibition of the Nuclear Export Receptor XPO1 as a Therapeutic Target for Platinum-Resistant Ovarian Cancer

(2016) Ying Chen et al.   CLINICAL CANCER RESEARCH

C-Type Lectin-Like Receptor 2 Suppresses AKT Signaling and Invasive Activities of Gastric Cancer Cells by Blocking Expression of Phosphoinositide 3-Kinase Subunits

(2016) Lan Wang et al.   GASTROENTEROLOGY

Regorafenib for the Treatment of Advanced Gastric Cancer (INTEGRATE): A Multinational Placebo-Controlled Phase II Trial

(2016) Nick Pavlakis et al.   JOURNAL OF CLINICAL ONCOLOGY

Morbidity and Mortality of Laparoscopic Versus Open D2 Distal Gastrectomy for Advanced Gastric Cancer: A Randomized Controlled Trial

(2016) Yanfeng Hu et al.   JOURNAL OF CLINICAL ONCOLOGY

TUSC3 promotes colorectal cancer progression and epithelial-mesenchymal transition (EMT) through WNT/β-catenin and MAPK signalling

(2016) Ye Gu et al.   JOURNAL OF PATHOLOGY

Activation of CK1ɛ by PP2A/PR61ɛ is required for the initiation of Wnt signaling

(2016) M Vinyoles et al.   ONCOGENE

Bcl-2 overexpression contributes to laryngeal carcinoma cell survival by forming a complex with Hsp90β

(2016) Sai Li et al.   ONCOLOGY REPORTS

Atomic structure of Hsp90-Cdc37-Cdk4 reveals that Hsp90 traps and stabilizes an unfolded kinase

(2016) K. A. Verba et al.   SCIENCE

FAT4 functions as a tumour suppressor in gastric cancer by modulating Wnt/β-catenin signalling

(2015) Jian Cai et al.   BRITISH JOURNAL OF CANCER

Proton pump inhibitor pantoprazole abrogates adriamycin-resistant gastric cancer cell invasiveness via suppression of Akt/GSK-β/β-catenin signaling and epithelial–mesenchymal transition

(2015) Bin Zhang et al.   CANCER LETTERS

miR-544ainduces epithelial–mesenchymal transition through the activation of WNT signaling pathway in gastric cancer

(2015) Yoshimitsu Yanaka et al.   CARCINOGENESIS

MDGA2 is a novel tumour suppressor cooperating with DMAP1 in gastric cancer and is associated with disease outcome

(2015) Kunning Wang et al.   GUT

High-level expression of Hsp90β is associated with poor survival in resectable non-small-cell lung cancer patients

(2015) Seok-Hyun Kim et al.   HISTOPATHOLOGY

Topically Applied Hsp90 Inhibitor 17AAG Inhibits UVR-Induced Cutaneous Squamous Cell Carcinomas

(2015) Anupama Singh et al.   JOURNAL OF INVESTIGATIVE DERMATOLOGY

AMPKα2 reduces renal epithelial transdifferentiation and inflammation after injury through interaction with CK2β

(2015) Shulan Qiu et al.   JOURNAL OF PATHOLOGY

Melatonin set out to ER stress signaling thwarts epithelial mesenchymal transition and peritoneal dissemination via calpain-mediated C/EBPβand NFκB cleavage

(2015) Sheng-Mao Wu et al.   JOURNAL OF PINEAL RESEARCH

Honokiol confers immunogenicity by dictating calreticulin exposure, activating ER stress and inhibiting epithelial-to-mesenchymal transition

(2015) Shing-Hwa Liu et al.   Molecular Oncology

SMYD2-dependent HSP90 methylation promotes cancer cell proliferation by regulating the chaperone complex formation

(2014) Ryuji Hamamoto et al.   CANCER LETTERS

Epigenetic modulation and repression of miR-200b by cancer-associated fibroblasts contribute to cancer invasion and peritoneal dissemination in gastric cancer

(2014) Junji Kurashige et al.   CARCINOGENESIS

SRF expedites metastasis and modulates the epithelial to mesenchymal transition by regulating miR-199a-5p expression in human gastric cancer

(2014) X Zhao et al.   CELL DEATH AND DIFFERENTIATION

Heat shock protein 90β stabilizes focal adhesion kinase and enhances cell migration and invasion in breast cancer cells

(2014) Xiangyang Xiong et al.   EXPERIMENTAL CELL RESEARCH

TAS-116, a Highly Selective Inhibitor of Heat Shock Protein 90  and  , Demonstrates Potent Antitumor Activity and Minimal Ocular Toxicity in Preclinical Models

(2014) S. Ohkubo et al.   MOLECULAR CANCER THERAPEUTICS

TACC3 promotes epithelial–mesenchymal transition (EMT) through the activation of PI3K/Akt and ERK signaling pathways

(2013) Geun-Hyoung Ha et al.   CANCER LETTERS

Tetraspanin TSPAN12 regulates tumor growth and metastasis and inhibits β-catenin degradation

(2013) Konstantin Knoblich et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

JMJD2B Promotes Epithelial-Mesenchymal Transition by Cooperating with  -Catenin and Enhances Gastric Cancer Metastasis

(2013) L. Zhao et al.   CLINICAL CANCER RESEARCH

Caveolin-1 promotes gastric cancer progression by up-regulating epithelial to mesenchymal transition by crosstalk of signalling mechanisms under hypoxic condition

(2013) Anbarasu Kannan et al.   EUROPEAN JOURNAL OF CANCER

The hemopexin domain of MMP3 is responsible for mammary epithelial invasion and morphogenesis through extracellular interaction with HSP90 

(2013) A. L. Correia et al.   GENES & DEVELOPMENT

EphA2 promotes epithelial–mesenchymal transition through the Wnt/β-catenin pathway in gastric cancer cells

(2013) J Huang et al.   ONCOGENE

Mass Spectrometry Compatible Surfactant for Optimized In-Gel Protein Digestion

(2012) Sergei V. Saveliev et al.   ANALYTICAL CHEMISTRY

MicroRNA-137, an HMGA1 Target, Suppresses Colorectal Cancer Cell Invasion and Metastasis in Mice by Directly Targeting FMNL2

(2012) Li Liang et al.   GASTROENTEROLOGY

Hsp90 stabilizes Cdc25A and counteracts heat shock-mediated Cdc25A degradation and cell-cycle attenuation in pancreatic carcinoma cells

(2012) B. Giessrigl et al.   HUMAN MOLECULAR GENETICS

Upregulation of Hsp90-beta and annexin A1 correlates with poor survival and lymphatic metastasis in lung cancer patients

(2012) Rong Biaoxue et al.   JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH

β-catenin as a potential key target for tumor suppression

(2011) Yuejun Fu et al.   INTERNATIONAL JOURNAL OF CANCER

Expression of HSP 90, PTEN and Bcl-2 in conjunctival melanoma

(2010) H. Westekemper et al.   BRITISH JOURNAL OF OPHTHALMOLOGY

A p120-catenin-CK1  complex regulates Wnt signaling

(2010) D. Casagolda et al.   JOURNAL OF CELL SCIENCE

Impact of heat-shock protein 90 on cancer metastasis

(2009) Shinji Tsutsumi et al.   Future Oncology

The basics of epithelial-mesenchymal transition

(2009) Raghu Kalluri et al.   JOURNAL OF CLINICAL INVESTIGATION

Interaction of heat-shock protein 90β isoform (HSP90β) with cellular inhibitor of apoptosis 1 (c-IAP1) is required for cell differentiation

(2008) C Didelot et al.   CELL DEATH AND DIFFERENTIATION

Heat Shock Protein 90 Overexpression Independently Predicts Inferior Disease-Free Survival with Differential Expression of the   and   Isoforms in Gastrointestinal Stromal Tumors

(2008) C.-F. Li et al.   CLINICAL CANCER RESEARCH