Mechanisms involved in the activation of C/EBPα by small activating RNA in hepatocellular carcinoma

Gene activation of CEBPA using saRNA: preclinical studies of the first in human saRNA drug candidate for liver cancer

(2018) Vikash Reebye et al.   ONCOGENE

Development and Mechanism of Small Activating RNA Targeting CEBPA, a Novel Therapeutic in Clinical Trials for Liver Cancer

(2017) Jon Voutila et al.   MOLECULAR THERAPY

A novel comparative pattern analysis approach identifies chronic alcohol mediated dysregulation of transcriptomic dynamics during liver regeneration

(2016) Lakshmi Kuttippurathu et al.   BMC GENOMICS

saRNA-guided Ago2 targets the RITA complex to promoters to stimulate transcription

(2016) Victoria Portnoy et al.   CELL RESEARCH

C/EBPα Short-Activating RNA Suppresses Metastasis of Hepatocellular Carcinoma through Inhibiting EGFR/β-Catenin Signaling Mediated EMT

(2016) Hongbo Huan et al.   PLoS One

Oncogenic role of p21 in hepatocarcinogenesis suggests a new treatment strategy

(2015) Shogo Ohkoshi   WORLD JOURNAL OF GASTROENTEROLOGY

Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012

(2014) Jacques Ferlay et al.   INTERNATIONAL JOURNAL OF CANCER

Deregulation of the endogenous C/EBPβ LIP isoform predisposes to tumorigenesis

(2014) Valérie Bégay et al.   JOURNAL OF MOLECULAR MEDICINE-JMM

Temporal mapping of CEBPA and CEBPB binding during liver regeneration reveals dynamic occupancy and specific regulatory codes for homeostatic and cell cycle gene batteries

(2013) J. S. Jakobsen et al.   GENOME RESEARCH

Novel RNA oligonucleotide improves liver function and inhibits liver carcinogenesisin vivo

(2013) Vikash Reebye et al.   HEPATOLOGY

Overactivation of the TGF-β pathway confers a mesenchymal-like phenotype and CXCR4-dependent migratory properties to liver tumor cells

(2013) Esther Bertran et al.   HEPATOLOGY

Complexity of CEBPA Dysregulation in Human Acute Myeloid Leukemia

(2009) T. Pabst et al.   CLINICAL CANCER RESEARCH