Role of astrocytes, microglia, and tanycytes in brain control of systemic metabolism

The Versatile Tanycyte: A Hypothalamic Integrator of Reproduction and Energy Metabolism

(2018) Vincent Prevot et al.   ENDOCRINE REVIEWS

Physiology of Astroglia

(2018) Alexei Verkhratsky et al.   PHYSIOLOGICAL REVIEWS

Deficiency of leptin receptor in myeloid cells disrupts hypothalamic metabolic circuits and causes body weight increase

(2018) Yuanqing Gao et al.   Molecular Metabolism

Hypothalamic Macrophage Inducible Nitric Oxide Synthase Mediates Obesity-Associated Hypothalamic Inflammation

(2018) Chan Hee Lee et al.   Cell Reports

Short-term high-fat diet increases the presence of astrocytes in the hypothalamus of C57BL6 mice without altering leptin sensitivity

(2017) E. Balland et al.   JOURNAL OF NEUROENDOCRINOLOGY

Gamma oscillations organize top-down signalling to hypothalamus and enable food seeking

(2017) Marta Carus-Cadavieco et al.   NATURE

Microglia emerge as central players in brain disease

(2017) Michael W Salter et al.   NATURE MEDICINE

The special relationship: glia–neuron interactions in the neuroendocrine hypothalamus

(2017) Jerome Clasadonte et al.   Nature Reviews Endocrinology

Connexin 43-Mediated Astroglial Metabolic Networks Contribute to the Regulation of the Sleep-Wake Cycle

(2017) Jerome Clasadonte et al.   NEURON

Astrocyte IKKβ/NF-κB signaling is required for diet-induced obesity and hypothalamic inflammation

(2017) J.D. Douglass et al.   Molecular Metabolism

Dietary sugars, not lipids, drive hypothalamic inflammation

(2017) Yuanqing Gao et al.   Molecular Metabolism

Heterogeneity of hypothalamic pro-opiomelanocortin-expressing neurons revealed by single-cell RNA sequencing

(2017) Brian Y.H. Lam et al.   Molecular Metabolism

High-fat diet-induced brain region-specific phenotypic spectrum of CNS resident microglia

(2016) Caroline Baufeld et al.   ACTA NEUROPATHOLOGICA

Expression of receptors for insulin and leptin in the ventral tegmental area/substantia nigra (VTA/SN) of the rat: Historical perspective

(2016) Dianne P. Figlewicz   BRAIN RESEARCH

AgRP Neurons Control Systemic Insulin Sensitivity via Myostatin Expression in Brown Adipose Tissue

(2016) Sophie M. Steculorum et al.   CELL

Astrocytic Insulin Signaling Couples Brain Glucose Uptake with Nutrient Availability

(2016) Cristina García-Cáceres et al.   CELL

Adult NG2-Glia Are Required for Median Eminence-Mediated Leptin Sensing and Body Weight Control

(2016) Tina Djogo et al.   Cell Metabolism

Inhibiting Microglia Expansion Prevents Diet-Induced Hypothalamic and Peripheral Inflammation

(2016) Caroline André et al.   DIABETES

Molecular interrogation of hypothalamic organization reveals distinct dopamine neuronal subtypes

(2016) Roman A Romanov et al.   NATURE NEUROSCIENCE

Hypothalamic arcuate nucleus tyrosine hydroxylase neurons play orexigenic role in energy homeostasis

(2016) Xiaobing Zhang et al.   NATURE NEUROSCIENCE

Agouti-related peptide neural circuits mediate adaptive behaviors in the starved state

(2016) Stephanie L Padilla et al.   NATURE NEUROSCIENCE

Microglial brain region−dependent diversity and selective regional sensitivities to aging

(2016) Kathleen Grabert et al.   NATURE NEUROSCIENCE

A rapidly acting glutamatergic ARC→PVH satiety circuit postsynaptically regulated by α-MSH

(2016) Henning Fenselau et al.   NATURE NEUROSCIENCE

The role of astrocytes in the hypothalamic response and adaptation to metabolic signals

(2016) Julie A. Chowen et al.   PROGRESS IN NEUROBIOLOGY

Sensory Detection of Food Rapidly Modulates Arcuate Feeding Circuits

(2015) Yiming Chen et al.   CELL

Hypothalamic Agrp Neurons Drive Stereotypic Behaviors beyond Feeding

(2015) Marcelo O. Dietrich et al.   CELL

Decoding Neural Circuits that Control Compulsive Sucrose Seeking

(2015) Edward H. Nieh et al.   CELL

Food for Thought: Revisiting the Complexity of Food Intake

(2015) Stephen C. Woods et al.   Cell Metabolism

Hypothalamic POMC neurons promote cannabinoid-induced feeding

(2015) Marco Koch et al.   NATURE

Neurons for hunger and thirst transmit a negative-valence teaching signal

(2015) J. Nicholas Betley et al.   NATURE

Diversity of astrocyte functions and phenotypes in neural circuits

(2015) Baljit S Khakh et al.   NATURE NEUROSCIENCE

AgRP Neurons Regulate Bone Mass

(2015) Jae Geun Kim et al.   Cell Reports

Astrocytes Control Food Intake by Inhibiting AGRP Neuron Activity via Adenosine A1 Receptors

(2015) Liang Yang et al.   Cell Reports

Arcuate hypothalamic AgRP and putative POMC neurons show opposite changes in spiking across multiple timescales

(2015) Yael Mandelblat-Cerf et al.   eLife

Neonatal overnutrition causes early alterations in the central response to peripheral ghrelin

(2015) Gustav Collden et al.   Molecular Metabolism

Hypothalamic Tanycytes Are an ERK-Gated Conduit for Leptin into the Brain

(2014) Eglantine Balland et al.   Cell Metabolism

Molecular and cellular regulation of hypothalamic melanocortin neurons controlling food intake and energy metabolism

(2014) M Koch et al.   MOLECULAR PSYCHIATRY

Leptin signaling in astrocytes regulates hypothalamic neuronal circuits and feeding

(2014) Jae Geun Kim et al.   NATURE NEUROSCIENCE

Gliotransmitters Travel in Time and Space

(2014) Alfonso Araque et al.   NEURON

Advances in the neurobiological bases for food ‘liking’ versus ‘wanting’

(2014) D.C. Castro et al.   PHYSIOLOGY & BEHAVIOR

Parallel, Redundant Circuit Organization for Homeostatic Control of Feeding Behavior

(2013) J. Nicholas Betley et al.   CELL

Mitofusin 2 in POMC Neurons Connects ER Stress with Leptin Resistance and Energy Imbalance

(2013) Marc Schneeberger et al.   CELL

Tanycytic VEGF-A Boosts Blood-Hypothalamus Barrier Plasticity and Access of Metabolic Signals to the Arcuate Nucleus in Response to Fasting

(2013) Fanny Langlet et al.   Cell Metabolism

Hormones and diet, but not body weight, control hypothalamic microglial activity

(2013) Yuanqing Gao et al.   GLIA

Hypothalamic Astroglial Connexins are Required for Brain Glucose Sensing-Induced Insulin Secretion

(2013) Camille Allard et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Microglia: New Roles for the Synaptic Stripper

(2013) Helmut Kettenmann et al.   NEURON

Hunger-promoting hypothalamic neurons modulate effector and regulatory T-cell responses

(2013) G. Matarese et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Obesity-driven synaptic remodeling affects endocannabinoid control of orexinergic neurons

(2013) L. Cristino et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid sensing of circulating ghrelin by hypothalamic appetite-modifying neurons

(2013) Marie Schaeffer et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hypothalamic control of energy balance: insights into the role of synaptic plasticity

(2013) Marcelo O. Dietrich et al.   TRENDS IN NEUROSCIENCES

GABAergic RIP-Cre Neurons in the Arcuate Nucleus Selectively Regulate Energy Expenditure

(2012) Dong Kong et al.   CELL

High-fat-diet exposure induces IgG accumulation in hypothalamic microglia

(2012) C.-X. Yi et al.   Disease Models & Mechanisms

Hypothalamic AgRP-neurons control peripheral substrate utilization and nutrient partitioning

(2012) Aurélie Joly-Amado et al.   EMBO JOURNAL

AgRP neurons: a switch between peripheral carbohydrate and lipid utilization

(2012) Luis Varela et al.   EMBO JOURNAL

Leptin regulates glutamate and glucose transporters in hypothalamic astrocytes

(2012) Esther Fuente-Martín et al.   JOURNAL OF CLINICAL INVESTIGATION

High calorie diet triggers hypothalamic angiopathy

(2012) Chun-Xia Yi et al.   Molecular Metabolism

Glucose Transporter-1 in the Hypothalamic Glial Cells Mediates Glucose Sensing to Regulate Glucose Production In Vivo

(2011) M. Chari et al.   DIABETES

Rapid, reversible activation of AgRP neurons drives feeding behavior in mice

(2011) Michael J. Krashes et al.   JOURNAL OF CLINICAL INVESTIGATION

Obesity is associated with hypothalamic injury in rodents and humans

(2011) Joshua P. Thaler et al.   JOURNAL OF CLINICAL INVESTIGATION

Glial Regulation of Neuronal Function: From Synapse to Systems Physiology

(2011) J. G. Tasker et al.   JOURNAL OF NEUROENDOCRINOLOGY

Peroxisome proliferation–associated control of reactive oxygen species sets melanocortin tone and feeding in diet-induced obesity

(2011) Sabrina Diano et al.   NATURE MEDICINE

Physiology of Microglia

(2011) Helmut Kettenmann et al.   PHYSIOLOGICAL REVIEWS

Steroidogenic factor 1 directs programs regulating diet-induced thermogenesis and leptin action in the ventral medial hypothalamic nucleus

(2011) K. W. Kim et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Synaptic input organization of the melanocortin system predicts diet-induced hypothalamic reactive gliosis and obesity

(2010) T. L. Horvath et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Loss of GABAergic Signaling by AgRP Neurons to the Parabrachial Nucleus Leads to Starvation

(2009) Qi Wu et al.   CELL

Saturated Fatty Acids Produce an Inflammatory Response Predominantly through the Activation of TLR4 Signaling in Hypothalamus: Implications for the Pathogenesis of Obesity

(2009) M. Milanski et al.   JOURNAL OF NEUROSCIENCE

Experience-dependent structural synaptic plasticity in the mammalian brain

(2009) Anthony Holtmaat et al.   NATURE REVIEWS NEUROSCIENCE

Astrocyte-Mediated Distributed Plasticity at Hypothalamic Glutamate Synapses

(2009) Grant R.J. Gordon et al.   NEURON

Contributions of the hippocampus and medial prefrontal cortex to energy and body weight regulation

(2008) Terry L. Davidson et al.   HIPPOCAMPUS

Prolactin and dopamine: What is the connection? A Review Article

(2008) Peter Fitzgerald et al.   JOURNAL OF PSYCHOPHARMACOLOGY

Widespread reward-system activation in obese women in response to pictures of high-calorie foods

(2008) Luke E. Stoeckel et al.   NEUROIMAGE

Starvation after AgRP neuron ablation is independent of melanocortin signaling

(2008) Q. Wu et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Astroglial Metabolic Networks Sustain Hippocampal Synaptic Transmission

(2008) N. Rouach et al.   SCIENCE