Identifying loci affecting trait variability and detecting interactions in genome-wide association studies

Effect of sequence variants on variance in glucose levels predicts type 2 diabetes risk and accounts for heritability

(2017) Erna V Ivarsdottir et al.   NATURE GENETICS

Protein-altering variants associated with body mass index implicate pathways that control energy intake and expenditure in obesity

(2017) Valérie Turcot et al.   NATURE GENETICS

Genetic determinants of adiponectin regulation revealed by pregnancy

(2017) Marie-France Hivert et al.   Obesity

Genome-wide meta-analysis uncovers novel loci influencing circulating leptin levels

(2016) Tuomas O. Kilpeläinen et al.   Nature Communications

Genetic studies of body mass index yield new insights for obesity biology

(2015) Adam E. Locke et al.   NATURE

LD Score regression distinguishes confounding from polygenicity in genome-wide association studies

(2015) Brendan K Bulik-Sullivan et al.   NATURE GENETICS

Progress and promise in understanding the genetic basis of common diseases

(2015) Alkes L. Price et al.   PROCEEDINGS OF THE ROYAL SOCIETY B-BIOLOGICAL SCIENCES

The Multi-allelic Genetic Architecture of a Variance-Heterogeneity Locus for Molybdenum Concentration in Leaves Acts as a Source of Unexplained Additive Genetic Variance

(2015) Simon K. G. Forsberg et al.   PLoS Genetics

UK Biobank: An Open Access Resource for Identifying the Causes of a Wide Range of Complex Diseases of Middle and Old Age

(2015) Cathie Sudlow et al.   PLOS MEDICINE

A Family-Based Joint Test for Mean and Variance Heterogeneity for Quantitative Traits

(2014) Ying Cao et al.   ANNALS OF HUMAN GENETICS

Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche

(2014) John R. B. Perry et al.   NATURE

Advantages and pitfalls in the application of mixed-model association methods

(2014) Jian Yang et al.   NATURE GENETICS

A Versatile Omnibus Test for Detecting Mean and Variance Heterogeneity

(2013) Ying Cao et al.   GENETIC EPIDEMIOLOGY

Recent developments in statistical methods for detecting genetic loci affecting phenotypic variability

(2012) Lars Rönnegård et al.   BMC GENETICS

FTO genotype is associated with phenotypic variability of body mass index

(2012) Jian Yang et al.   NATURE

New loci associated with birth weight identify genetic links between intrauterine growth and adult height and metabolism

(2012) Momoko Horikoshi et al.   NATURE GENETICS

Genetic analysis of environmental variation

(2011) WILLIAM G. HILL et al.   Genetics Research

FaST linear mixed models for genome-wide association studies

(2011) Christoph Lippert et al.   NATURE METHODS

Variance heterogeneity analysis for detection of potentially interacting genetic loci: method and its limitations

(2010) Maksim V Struchalin et al.   BMC GENETICS

Variants in ADCY5 and near CCNL1 are associated with fetal growth and birth weight

(2010) Rachel M Freathy et al.   NATURE GENETICS

Mixed linear model approach adapted for genome-wide association studies

(2010) Zhiwu Zhang et al.   NATURE GENETICS

On the Use of Variance per Genotype as a Tool to Identify Quantitative Trait Interaction Effects: A Report from the Women's Genome Health Study

(2010) Guillaume Paré et al.   PLoS Genetics

Data and Theory Point to Mainly Additive Genetic Variance for Complex Traits

(2008) William G. Hill et al.   PLoS Genetics