EGFR signalling controls cellular fate and pancreatic organogenesis by regulating apicobasal polarity

Precommitment low-levelNeurog3expression defines a long-lived mitotic endocrine-biased progenitor pool that drives production of endocrine-committed cells

(2016) Matthew E. Bechard et al.   GENES & DEVELOPMENT

β-Catenin Regulates Primitive Streak Induction through Collaborative Interactions with SMAD2/SMAD3 and OCT4

(2015) Nina S. Funa et al.   Cell Stem Cell

Crumbs3-Mediated Polarity Directs Airway Epithelial Cell Fate through the Hippo Pathway Effector Yap

(2015) Aleksander D. Szymaniak et al.   DEVELOPMENTAL CELL

Feedback control of growth, differentiation, and morphogenesis of pancreatic endocrine progenitors in an epithelial plexus niche

(2015) Eric D. Bankaitis et al.   GENES & DEVELOPMENT

Cdc42/N-WASP signaling links actin dynamics to pancreatic   cell delamination and differentiation

(2014) G. Kesavan et al.   DEVELOPMENT

Reversal of diabetes with insulin-producing cells derived in vitro from human pluripotent stem cells

(2014) Alireza Rezania et al.   NATURE BIOTECHNOLOGY

An Integrated Cell Purification and Genomics Strategy Reveals Multiple Regulators of Pancreas Development

(2014) Cecil M. Benitez et al.   PLoS Genetics

EGFR signaling promotes self-renewal through the establishment of cell polarity in Drosophila follicle stem cells

(2014) Angela Castanieto et al.   eLife

Factors Expressed by Murine Embryonic Pancreatic Mesenchyme Enhance Generation of Insulin-Producing Cells From hESCs

(2013) T. Guo et al.   DIABETES

Characterization of the EGFR interactome reveals associated protein complex networks and intracellular receptor dynamics

(2013) Sarah Foerster et al.   PROTEOMICS

Polarity in Mammalian Epithelial Morphogenesis

(2013) J. Roignot et al.   Cold Spring Harbor Perspectives in Biology

Loss of Llgl1 in retinal neuroepithelia reveals links between apical domain size, Notch activity and neurogenesis

(2012) B. S. Clark et al.   DEVELOPMENT

β-Cell evolution: How the pancreas borrowed from the brain

(2011) Margot E. Arntfield et al.   BIOESSAYS

Neurogenin3 initiates stepwise delamination of differentiating endocrine cells during pancreas development

(2011) Mathieu Gouzi et al.   DEVELOPMENTAL DYNAMICS

A recombinase-mediated cassette exchange-derived cyan fluorescent protein reporter allele for Pdx1

(2011) Leah A. Potter et al.   GENESIS

Crumbs controls epithelial integrity by inhibiting Rac1 and PI3K

(2011) F. J.- M. Chartier et al.   JOURNAL OF CELL SCIENCE

Dual Roles of Notch in Regulation of Apically Restricted Mitosis and Apicobasal Polarity of Neuroepithelial Cells

(2011) Shinya Ohata et al.   NEURON

Epithelial dynamics of pancreatic branching morphogenesis

(2010) A. Villasenor et al.   DEVELOPMENT

Accurate and objective copy number profiling using real-time quantitative PCR

(2010) Barbara D’haene et al.   METHODS

NANOG Reporter Cell Lines Generated by Gene Targeting in Human Embryonic Stem Cells

(2010) Yvonne Fischer et al.   PLoS One

Cdc42-Mediated Tubulogenesis Controls Cell Specification

(2009) Gokul Kesavan et al.   CELL

Neurog3 gene dosage regulates allocation of endocrine and exocrine cell fates in the developing mouse pancreas

(2009) Sui Wang et al.   DEVELOPMENTAL BIOLOGY

PAR-1 Phosphorylates Mind Bomb to Promote Vertebrate Neurogenesis

(2009) Olga Ossipova et al.   DEVELOPMENTAL CELL

Regulation of Neurogenesis by Interkinetic Nuclear Migration through an Apical-Basal Notch Gradient

(2008) Filippo Del Bene et al.   CELL

Functional selectivity of EGF family peptide growth factors: Implications for cancer

(2008) Kristy J. Wilson et al.   PHARMACOLOGY & THERAPEUTICS

Polarity complex proteins

(2007) Emeline Assémat et al.   BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES