Endoplasmic reticulum stress mediates inflammatory response triggered by ultra-small superparamagnetic iron oxide nanoparticles in hepatocytes

Silica nanoparticles induce autophagosome accumulation via activation of the EIF2AK3 and ATF6 UPR pathways in hepatocytes

(2018) Ji Wang et al.   Autophagy

At the crossway of ER-stress and proinflammatory responses

(2018) Marisa Reverendo et al.   FEBS Journal

RNA sequencing analysis shows that titanium dioxide nanoparticles induce endoplasmic reticulum stress, which has a central role in mediating plasma glucose in mice

(2018) Hailong Hu et al.   Nanotoxicology

In-vitro toxicity induced by quartz nanoparticles: Role of ER stress

(2018) Sushma et al.   TOXICOLOGY

ER stress regulating protein phosphatase 2A-B56γ, targeted by hepatitis B virus X protein, induces cell cycle arrest and apoptosis of hepatocytes

(2018) Chengyong He et al.   Cell Death & Disease

Persistent phosphorylation at specific H3 serine residues involved in chemical carcinogen-induced cell transformation

(2017) Xiaonian Zhu et al.   MOLECULAR CARCINOGENESIS

For Better or Worse, Iron Overload by Superparamagnetic Iron Oxide Nanoparticles as a MRI Contrast Agent for Chronic Liver Diseases

(2016) Qibing Zhou et al.   CHEMICAL RESEARCH IN TOXICOLOGY

N-linked glycosylation and homeostasis of the endoplasmic reticulum

(2016) Natalia Cherepanova et al.   CURRENT OPINION IN CELL BIOLOGY

The Effects of Ferulic Acid Against Oxidative Stress and Inflammation in Formaldehyde-Induced Hepatotoxicity

(2016) Fethullah Gerin et al.   INFLAMMATION

CXCL14 as an emerging immune and inflammatory modulator

(2016) Jing Lu et al.   Journal of Inflammation-London

NOD1 and NOD2 signalling links ER stress with inflammation

(2016) A. Marijke Keestra-Gounder et al.   NATURE

Protein misfolding in the endoplasmic reticulum as a conduit to human disease

(2016) Miao Wang et al.   NATURE

Noninvasive Differentiation between Hepatic Steatosis and Steatohepatitis with MR Imaging Enhanced with USPIOs in Patients with Nonalcoholic Fatty Liver Disease: A Proof-of-Concept Study

(2016) Loek P. Smits et al.   RADIOLOGY

Ca2+ homeostasis and endoplasmic reticulum (ER) stress: An integrated view of calcium signaling

(2015) Joachim Krebs et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Endoplasmic reticulum stress-mediated inflammatory signaling pathways within the osteolytic periosteum and interface membrane in particle-induced osteolysis

(2015) Guoyin Liu et al.   CELL AND TISSUE RESEARCH

Acetylcholine ameliorates endoplasmic reticulum stress in endothelial cells after hypoxia/reoxygenation via M3 AChR-AMPK signaling

(2015) Xueyuan Bi et al.   CELL CYCLE

Design considerations for the synthesis of polymer coated iron oxide nanoparticles for stem cell labelling and tracking using MRI

(2015) Michael Barrow et al.   CHEMICAL SOCIETY REVIEWS

Synthesis and dose interval dependent hepatotoxicity evaluation of intravenously administered polyethylene glycol-8000 coated ultra-small superparamagnetic iron oxide nanoparticle on Wistar rats

(2015) Balan Rajan et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Endoplasmic Reticulum Stress Interacts With Inflammation in Human Diseases

(2015) Stewart Siyan Cao et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Endoplasmic reticulum stress and oxidative stress are involved in ZnO nanoparticle-induced hepatotoxicity

(2015) Xia Yang et al.   TOXICOLOGY LETTERS

Integration of Hippo signalling and the unfolded protein response to restrain liver overgrowth and tumorigenesis

(2015) Hongtan Wu et al.   Nature Communications

Surface Chemistry of Gold Nanoparticles Mediates Their Exocytosis in Macrophages

(2014) Nuri Oh et al.   ACS Nano

Endoplasmic Reticulum Stress Induced by Zinc Oxide Nanoparticles Is an Earlier Biomarker for Nanotoxicological Evaluation

(2014) Rui Chen et al.   ACS Nano

Magnetite- and maghemite-induced different toxicity in murine alveolar macrophage cells

(2014) Eun-Jung Park et al.   ARCHIVES OF TOXICOLOGY

Cellular internalization and detailed toxicity analysis of protein-immobilized iron oxide nanoparticles

(2014) Purva Sanganeria et al.   JOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS

Functional investigations on embryonic stem cells labeled with clinically translatable iron oxide nanoparticles

(2014) Jing Liu et al.   Nanoscale

Size-dependent cytotoxicity of silver nanoparticles in human lung cells: the role of cellular uptake, agglomeration and Ag release

(2014) Anda R Gliga et al.   Particle and Fibre Toxicology

Overexpression of Nrf2 Protects against Microcystin-Induced Hepatotoxicity in Mice

(2014) Yuan-Fu Lu et al.   PLoS One

Magnetic iron oxide nanoparticles induce autophagy preceding apoptosis through mitochondrial damage and ER stress in RAW264.7 cells

(2014) Eun-Jung Park et al.   TOXICOLOGY IN VITRO

IL-6 in Inflammation, Immunity, and Disease

(2014) T. Tanaka et al.   Cold Spring Harbor Perspectives in Biology

Endoplasmic reticulum stress in hepatic steatosis and inflammatory bowel diseases

(2014) Beichu Guo et al.   Frontiers in Genetics

Synthesis and toxicity characterization of carbon coated iron oxide nanoparticles with highly defined size distributions

(2013) Rafael Gregorio Mendes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS

Activating Transcription Factor 4 Links Metabolic Stress to Interleukin-6 Expression in Macrophages

(2013) Y. Iwasaki et al.   DIABETES

Magnetic resonance imaging tracking of ultra small superparamagnetic iron oxide labeled rabbit dendritic cells

(2013) Jing Zhou et al.   EXPERIMENTAL BIOLOGY AND MEDICINE

Mitochondrial and endoplasmic reticulum pathways involved in microcystin-LR-induced apoptosis of the testes of male frog (Rana nigromaculata) in vivo

(2013) Hangjun Zhang et al.   JOURNAL OF HAZARDOUS MATERIALS

Role of size and surface area for pro-inflammatory responses to silica nanoparticles in epithelial lung cells: Importance of exposure conditions

(2013) T. Skuland et al.   TOXICOLOGY IN VITRO

ER stress upregulated PGE2/IFNγ-induced IL-6 expression and down-regulated iNOS expression in glial cells

(2013) Toru Hosoi et al.   Scientific Reports

LDL-cholesterol versus HDL-cholesterol in the atherosclerotic plaque: inflammatory resolution versus thrombotic chaos

(2012) Lina Badimon et al.   Annals of the New York Academy of Sciences

Size influences the cytotoxicity of poly (lactic-co-glycolic acid) (PLGA) and titanium dioxide (TiO2) nanoparticles

(2012) Sijing Xiong et al.   ARCHIVES OF TOXICOLOGY

ATF4 is directly recruited by TLR4 signaling and positively regulates TLR4-trigged cytokine production in human monocytes

(2012) Chunyan Zhang et al.   Cellular & Molecular Immunology

Cell motility of neural stem cells is reduced after SPIO-labeling, which is mitigated after exocytosis

(2012) Stacey M. Cromer Berman et al.   MAGNETIC RESONANCE IN MEDICINE

IFN-α-driven CCL2 production recruits inflammatory monocytes to infection site in mice

(2012) C D Conrady et al.   Mucosal Immunology

Lactate dehydrogenase as a marker of nasopharyngeal inflammatory injury during viral upper respiratory infection: implications for acute otitis media

(2012) Linda C. Ede et al.   PEDIATRIC RESEARCH

Applications and Potential Toxicity of Magnetic Iron Oxide Nanoparticles

(2012) Gang Liu et al.   Small

A metabonomic analysis of organ specific response to USPIO administration

(2011) Jianghua Feng et al.   BIOMATERIALS

Inflammatory and cytotoxic responses of an alveolar-capillary coculture model to silica nanoparticles: Comparison with conventional monocultures

(2011) Jennifer Kasper et al.   Particle and Fibre Toxicology

Efficient internalization of silica-coated iron oxide nanoparticles of different sizes by primary human macrophages and dendritic cells

(2011) Andrea Kunzmann et al.   TOXICOLOGY AND APPLIED PHARMACOLOGY

Superparamagnetic iron oxide nanoparticles (SPIONs): Development, surface modification and applications in chemotherapy

(2010) Morteza Mahmoudi et al.   ADVANCED DRUG DELIVERY REVIEWS

The effect of carboxydextran-coated superparamagnetic iron oxide nanoparticles on c-Jun N-terminal kinase-mediated apoptosis in human macrophages

(2010) Oleg Lunov et al.   BIOMATERIALS

Low molecular weight alkyl-polycation wrapped magnetite nanoparticle clusters as MRI probes for stem cell labeling and in vivo imaging

(2010) Gang Liu et al.   BIOMATERIALS

Endoplasmic Reticulum Stress and Inflammation in Obesity and Diabetes

(2010) Sarah Hummasti et al.   CIRCULATION RESEARCH

FFA-Induced Adipocyte Inflammation and Insulin Resistance: Involvement of ER Stress and IKKβ Pathways

(2010) Ping Jiao et al.   Obesity

Inducible Nitric Oxide Synthase Deficiency Impairs Matrix Metalloproteinase-9 Activity and Disrupts Leukocyte Migration in Hepatic Ischemia/Reperfusion Injury

(2009) Takashi Hamada et al.   AMERICAN JOURNAL OF PATHOLOGY

Mitochondrial Dysfunction and Reactive Oxygen Species Imbalance Promote Breast Cancer Cell Motility through a CXCL14-Mediated Mechanism

(2009) H. Pelicano et al.   CANCER RESEARCH

The Inflammatory Response to Cell Death

(2008) Kenneth L. Rock et al.   Annual Review of Pathology-Mechanisms of Disease