Reduced presynaptic vesicle stores mediate cellular and network plasticity defects in an early-stage mouse model of Alzheimer’s disease

GABAA receptor subunit expression changes in the human Alzheimer's disease hippocampus, subiculum, entorhinal cortex and superior temporal gyrus

(2018) Andrea Kwakowsky et al.   JOURNAL OF NEUROCHEMISTRY

Changes in Brain Volume and Cognition in a Randomized Trial of Exercise and Social Interaction in a Community-Based Sample of Non-Demented Chinese Elders

(2018) James A. Mortimer et al.   JOURNAL OF ALZHEIMERS DISEASE

Long-Term Cannabidiol Treatment Prevents the Development of Social Recognition Memory Deficits in Alzheimer's Disease Transgenic Mice

(2018) David Cheng et al.   JOURNAL OF ALZHEIMERS DISEASE

A Cell Atlas for the Mouse Brain

(2018) Csaba Erö et al.   Frontiers in Neuroinformatics

Familial Alzheimer's Disease Mutations in Presenilins: Effects on Endoplasmic Reticulum Calcium Homeostasis and Correlation with Clinical Phenotypes

(2017) Omar Nelson et al.   JOURNAL OF ALZHEIMERS DISEASE

Subtle behavioral changes and increased prefrontal-hippocampal network synchronicity in APPNL−G−F mice before prominent plaque deposition

(2017) Amira Latif-Hernandez et al.   BEHAVIOURAL BRAIN RESEARCH

Calcium-Dependent Protein Kinase C Is Not Required for Post-Tetanic Potentiation at the Hippocampal CA3 to CA1 Synapse

(2016) Chih-Chieh Wang et al.   JOURNAL OF NEUROSCIENCE

Dynamic Alterations of Rat Nucleus Accumbens Dendritic Spines over 2 Months of Abstinence from Extended-Access Cocaine Self-Administration

(2016) Daniel T Christian et al.   NEUROPSYCHOPHARMACOLOGY

Aberrant expression of the pore-forming KATP channel subunit Kir6.2 in hippocampal reactive astrocytes in the 3xTg-AD mouse model and human Alzheimer’s disease

(2016) Chelsea M. Griffith et al.   NEUROSCIENCE

Behavioural Phenotyping of APPswe/PS1δE9 Mice: Age-Rrelated Changes and Effect of Long-Term Paroxetine Treatment

(2016) Louise Ørum Olesen et al.   PLoS One

Reference and working memory deficits in the 3xTg-AD mouse between 2 and 15-months of age: A cross-sectional study

(2015) Leanne M. Stevens et al.   BEHAVIOURAL BRAIN RESEARCH

Ryanodine-mediated conversion of STP to LTP is lacking in synaptopodin-deficient mice

(2015) Gayane Grigoryan et al.   Brain Structure & Function

Nitric Oxide Signaling Is Recruited As a Compensatory Mechanism for Sustaining Synaptic Plasticity in Alzheimer's Disease Mice

(2015) S. Chakroborty et al.   JOURNAL OF NEUROSCIENCE

Neuronal Store-Operated Calcium Entry and Mushroom Spine Loss in Amyloid Precursor Protein Knock-In Mouse Model of Alzheimer's Disease

(2015) H. Zhang et al.   JOURNAL OF NEUROSCIENCE

The mechanisms and functions of spontaneous neurotransmitter release

(2015) Ege T. Kavalali   NATURE REVIEWS NEUROSCIENCE

Alterations in synaptic plasticity coincide with deficits in spatial working memory in presymptomatic 3xTg-AD mice

(2015) Jason K. Clark et al.   NEUROBIOLOGY OF LEARNING AND MEMORY

Appearance of fast astrocytic component in voltage-sensitive dye imaging of neural activity

(2015) Ildikó Pál et al.   Molecular Brain

Behavioral Tagging: A Translation of the Synaptic Tagging and Capture Hypothesis

(2015) Diego Moncada et al.   NEURAL PLASTICITY

Functional optical probing of the hippocampal trisynaptic circuit in vitro: network dynamics, filter properties, and polysynaptic induction of CA1 LTP

(2015) Jens Stepan et al.   Frontiers in Neuroscience

Knock-In of Human BACE1 Cleaves Murine APP and Reiterates Alzheimer-like Phenotypes

(2014) K. Pluci ska et al.   JOURNAL OF NEUROSCIENCE

Ryanodine receptors: physiological function and deregulation in Alzheimer disease

(2014) Dolores Del Prete et al.   Molecular Neurodegeneration

Interplay between Short- and Long-Term Plasticity in Cell-Assembly Formation

(2014) Naoki Hiratani et al.   PLoS One

Aberrant calcium signaling by transglutaminase-mediated posttranslational modification of inositol 1,4,5-trisphosphate receptors

(2014) K. Hamada et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Short-Term Plasticity Explains Irregular Persistent Activity in Working Memory Tasks

(2013) D. Hansel et al.   JOURNAL OF NEUROSCIENCE

Synaptic Regulation of Microtubule Dynamics in Dendritic Spines by Calcium, F-Actin, and Drebrin

(2013) E. B. Merriam et al.   JOURNAL OF NEUROSCIENCE

Inhibitory Neuron and Hippocampal Circuit Dysfunction in an Aged Mouse Model of Alzheimer's Disease

(2013) Anupam Hazra et al.   PLoS One

Dysregulation of neural calcium signaling in Alzheimer disease, bipolar disorder and schizophrenia

(2013) Michael J. Berridge   Prion

Dendritic spines: from structure to in vivo function

(2012) Nathalie L Rochefort et al.   EMBO REPORTS

Early Presynaptic and Postsynaptic Calcium Signaling Abnormalities Mask Underlying Synaptic Depression in Presymptomatic Alzheimer's Disease Mice

(2012) S. Chakroborty et al.   JOURNAL OF NEUROSCIENCE

The Number and Organization of Ca2+ Channels in the Active Zone Shapes Neurotransmitter Release from Schaffer Collateral Synapses

(2012) A. Scimemi et al.   JOURNAL OF NEUROSCIENCE

OLM interneurons differentially modulate CA3 and entorhinal inputs to hippocampal CA1 neurons

(2012) Richardson N Leão et al.   NATURE NEUROSCIENCE

Sex-Dependent Alterations in Social Behaviour and Cortical Synaptic Activity Coincide at Different Ages in a Model of Alzheimer’s Disease

(2012) Cyril Bories et al.   PLoS One

Stabilizing ER Ca2+ Channel Function as an Early Preventative Strategy for Alzheimer’s Disease

(2012) Shreaya Chakroborty et al.   PLoS One

Altered Calcium Signaling Following Traumatic Brain Injury

(2012) John T. Weber   Frontiers in Pharmacology

Short-term forms of presynaptic plasticity

(2011) Diasynou Fioravante et al.   CURRENT OPINION IN NEUROBIOLOGY

Extrinsic and local glutamatergic inputs of the rat hippocampal CA1 area differentially innervate pyramidal cells and interneurons

(2011) Virág T. Takács et al.   HIPPOCAMPUS

Reduced Spine Density in Specific Regions of CA1 Pyramidal Neurons in Two Transgenic Mouse Models of Alzheimer's Disease

(2011) C. Perez-Cruz et al.   JOURNAL OF NEUROSCIENCE

Differential Control of Presynaptic CaMKII Activation and Translocation to Active Zones

(2011) D. Shakiryanova et al.   JOURNAL OF NEUROSCIENCE

Abnormal Presynaptic Short-Term Plasticity and Information Processing in a Mouse Model of Fragile X Syndrome

(2011) P.-Y. Deng et al.   JOURNAL OF NEUROSCIENCE

Hippocampal microcircuit dynamics probed using optical imaging approaches

(2011) Douglas A. Coulter et al.   JOURNAL OF PHYSIOLOGY-LONDON

High-throughput, detailed, cell-specific neuroanatomy of dendritic spines using microinjection and confocal microscopy

(2011) Dani Dumitriu et al.   Nature Protocols

Altered ryanodine receptor expression in mild cognitive impairment and Alzheimer's disease

(2011) Angela M. Bruno et al.   NEUROBIOLOGY OF AGING

Altered presynaptic ultrastructure in excitatory hippocampal synapses of mice lacking dystrophins Dp427 or Dp71

(2011) Rubén Miranda et al.   NEUROBIOLOGY OF DISEASE

Hippocampal synaptic plasticity in Alzheimer’s disease: what have we learned so far from transgenic models?

(2011) Cristina Marchetti et al.   REVIEWS IN THE NEUROSCIENCES

Early calcium dysregulation in Alzheimer’s disease: setting the stage for synaptic dysfunction

(2011) Shreaya Chakroborty et al.   Science China-Life Sciences

Generation of dendritic Ca2+oscillations as a consequence of altered ryanodine receptor function in AD neurons

(2010) Ivan Goussakov et al.   Channels

N-cadherin mediates plasticity-induced long-term spine stabilization

(2010) Pablo Mendez et al.   JOURNAL OF CELL BIOLOGY

Post-tetanic increase in the fast-releasing synaptic vesicle pool at the expense of the slowly releasing pool

(2010) Jae Sung Lee et al.   JOURNAL OF GENERAL PHYSIOLOGY

N-Methyl-d-aspartate receptors are required for synaptic targeting of Alzheimer’s toxic amyloid-β peptide oligomers

(2010) Helena Decker et al.   JOURNAL OF NEUROCHEMISTRY

Amphetamine-Associated Contextual Learning Is Accompanied by Structural and Functional Plasticity in the Basolateral Amygdala

(2010) D. J. Rademacher et al.   JOURNAL OF NEUROSCIENCE

NMDA-Mediated Ca2+ Influx Drives Aberrant Ryanodine Receptor Activation in Dendrites of Young Alzheimer's Disease Mice

(2010) I. Goussakov et al.   JOURNAL OF NEUROSCIENCE

Amyloid   Induces the Morphological Neurodegenerative Triad of Spine Loss, Dendritic Simplification, and Neuritic Dystrophies through Calcineurin Activation

(2010) H.-Y. Wu et al.   JOURNAL OF NEUROSCIENCE

Selective Changes in Thin Spine Density and Morphology in Monkey Prefrontal Cortex Correlate with Aging-Related Cognitive Impairment

(2010) D. Dumitriu et al.   JOURNAL OF NEUROSCIENCE

Post-tetanic potentiation is caused by two signalling mechanisms affecting quantal size and quantal content

(2010) Lei Xue et al.   JOURNAL OF PHYSIOLOGY-LONDON

Making memories last: the synaptic tagging and capture hypothesis

(2010) Roger L. Redondo et al.   NATURE REVIEWS NEUROSCIENCE

Structural dynamics of dendritic spines in memory and cognition

(2010) Haruo Kasai et al.   TRENDS IN NEUROSCIENCES

Deviant Ryanodine Receptor-Mediated Calcium Release Resets Synaptic Homeostasis in Presymptomatic 3xTg-AD Mice

(2009) S. Chakroborty et al.   JOURNAL OF NEUROSCIENCE

Priming of short-term potentiation and synaptic tagging/capture mechanisms by ryanodine receptor activation in rat hippocampal CA1

(2009) S. Sajikumar et al.   LEARNING & MEMORY

Membrane potential response profiles of CA1 pyramidal cells probed with voltage-sensitive dye optical imaging in rat hippocampal slices reveal the impact of GABAA-mediated feed-forward inhibition in signal propagation

(2009) Yoko Tominaga et al.   NEUROSCIENCE RESEARCH

Oligomeric amyloid   associates with postsynaptic densities and correlates with excitatory synapse loss near senile plaques

(2009) R. M. Koffie et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Actin in action: the interplay between the actin cytoskeleton and synaptic efficacy

(2008) Lorenzo A. Cingolani et al.   NATURE REVIEWS NEUROSCIENCE

Mechanism of Ca2+ Disruption in Alzheimer's Disease by Presenilin Regulation of InsP3 Receptor Channel Gating

(2008) King-Ho Cheung et al.   NEURON

Calcium Signaling in Dendrites and Spines: Practical and Functional Considerations

(2008) Michael J. Higley et al.   NEURON

Aβ Plaques Lead to Aberrant Regulation of Calcium Homeostasis In Vivo Resulting in Structural and Functional Disruption of Neuronal Networks

(2008) Kishore V. Kuchibhotla et al.   NEURON

Cadherins and catenins at synapses: roles in synaptogenesis and synaptic plasticity

(2008) Jyothi Arikkath et al.   TRENDS IN NEUROSCIENCES

Neuronal calcium mishandling and the pathogenesis of Alzheimer's disease

(2008) Ilya Bezprozvanny et al.   TRENDS IN NEUROSCIENCES