Mitochondrial Neuroglobin Is Necessary for Protection Induced by Conditioned Medium from Human Adipose-Derived Mesenchymal Stem Cells in Astrocytic Cells Subjected to Scratch and Metabolic Injury

TLR-induced immunomodulatory cytokine expression by human gingival stem/progenitor cells

(2018) Mohamed K. Mekhemar et al.   CELLULAR IMMUNOLOGY

Inflammation in CNS neurodegenerative diseases

(2018) Jodie Stephenson et al.   IMMUNOLOGY

Effects of interleukin-6 and IL-6/AMPK signaling pathway on mitochondrial biogenesis and astrocytes viability under experimental septic condition

(2018) Xiao-Lan Chen et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Mesenchymal Stem Cell Protection of Neurons against Glutamate Excitotoxicity Involves Reduction of NMDA-Triggered Calcium Responses and Surface GluR1, and Is Partly Mediated by TNF

(2018) Irini Papazian et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

The therapeutic potential of the mesenchymal stem cell secretome in ischaemic stroke

(2018) Catriona J Cunningham et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Paracrine Anti-inflammatory Effects of Adipose Tissue-Derived Mesenchymal Stem Cells in Human Monocytes

(2018) Maria I. Guillén et al.   Frontiers in Physiology

The Inflammatory Continuum of Traumatic Brain Injury and Alzheimer’s Disease

(2018) Olga N. Kokiko-Cochran et al.   Frontiers in Immunology

Autophagy controls the pathogenicity of OPA1 mutations in dominant optic atrophy

(2017) Mariame Selma Kane et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

The Plasticity and Stability of Regulatory T Cells during Viral-Induced Inflammatory Lesions

(2017) Siddheshvar Bhela et al.   JOURNAL OF IMMUNOLOGY

Conditioned Medium of Human Adipose Mesenchymal Stem Cells Increases Wound Closure and Protects Human Astrocytes Following Scratch Assay In Vitro

(2017) Eliana Baez-Jurado et al.   MOLECULAR NEUROBIOLOGY

Tibolone Reduces Oxidative Damage and Inflammation in Microglia Stimulated with Palmitic Acid through Mechanisms Involving Estrogen Receptor Beta

(2017) Oscar Hidalgo-Lanussa et al.   MOLECULAR NEUROBIOLOGY

PDGF-BB Preserves Mitochondrial Morphology, Attenuates ROS Production, and Upregulates Neuroglobin in an Astrocytic Model Under Rotenone Insult

(2017) Ricardo Cabezas et al.   MOLECULAR NEUROBIOLOGY

Blockade of Neuroglobin Reduces Protection of Conditioned Medium from Human Mesenchymal Stem Cells in Human Astrocyte Model (T98G) Under a Scratch Assay

(2017) Eliana Baez-Jurado et al.   MOLECULAR NEUROBIOLOGY

Recombinant human erythropoietin offers neuroprotection through inducing endogenous erythropoietin receptor and neuroglobin in a neonatal rat model of periventricular white matter damage

(2017) Lihua Zhu et al.   NEUROSCIENCE LETTERS

Cadmium-induced IL-6 and IL-8 expression and release from astrocytes are mediated by MAPK and NF-κB pathways

(2017) Suttinee Phuagkhaopong et al.   NEUROTOXICOLOGY

Brain and Peripheral Atypical Inflammatory Mediators Potentiate Neuroinflammation and Neurodegeneration

(2017) Duraisamy Kempuraj et al.   Frontiers in Cellular Neuroscience

Oxygen and Glucose Deprivation Induces Bergmann Glia Membrane Depolarization and Ca2+ Rises Mainly Mediated by K+ and ATP Increases in the Extracellular Space

(2017) Romain Helleringer et al.   Frontiers in Cellular Neuroscience

The Role of Astrocytes in Neuroprotection after Brain Stroke: Potential in Cell Therapy

(2017) Andrea Becerra-Calixto et al.   Frontiers in Molecular Neuroscience

Cell cycle arrest and biochemical changes accompanying cell death in harmful dinoflagellates following exposure to bacterial algicide IRI-160AA

(2017) Kaytee L. Pokrzywinski et al.   Scientific Reports

Hypermetabolism and hypercatabolism of skeletal muscle accompany mitochondrial stress following severe burn trauma

(2016) John O. Ogunbileje et al.   AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM

Protection of Brain Injury by Amniotic Mesenchymal Stromal Cell-Secreted Metabolites

(2016) Francesca Pischiutta et al.   CRITICAL CARE MEDICINE

Microglial genes regulating neuroinflammation in the progression of Alzheimer's disease

(2016) Claudio Villegas-Llerena et al.   CURRENT OPINION IN NEUROBIOLOGY

Comparative analysis of the immunomodulatory capacities of human bone marrow– and adipose tissue–derived mesenchymal stromal cells from the same donor

(2016) Jaris Valencia et al.   CYTOTHERAPY

The current landscape of the mesenchymal stromal cell secretome: A new paradigm for cell-free regeneration

(2016) Vijay Bhaskar Reddy Konala et al.   CYTOTHERAPY

Metabolic regulation of mitochondrial dynamics

(2016) Prashant Mishra et al.   JOURNAL OF CELL BIOLOGY

Neuroglobin protects astroglial cells from hydrogen peroxide-induced oxidative stress and apoptotic cell death

(2016) Fatma Amri et al.   JOURNAL OF NEUROCHEMISTRY

Tibolone protects astrocytic cells from glucose deprivation through a mechanism involving estrogen receptor beta and the upregulation of neuroglobin expression

(2016) Marco Avila-Rodriguez et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

Role of neuroinflammation in neurodegenerative diseases (Review)

(2016) WEI-WEI CHEN et al.   Molecular Medicine Reports

Inflammatory Response in the CNS: Friend or Foe?

(2016) Marta Sochocka et al.   MOLECULAR NEUROBIOLOGY

Astrocytes: Integrative Regulators of Neuroinflammation in Stroke and Other Neurological Diseases

(2016) Egle Cekanaviciute et al.   Neurotherapeutics

Effect of Secreted Molecules of Human Embryonic Stem Cell-Derived Mesenchymal Stem Cells on Acute Hepatic Failure Model

(2016) Majid Lotfinia et al.   STEM CELLS AND DEVELOPMENT

Astrocytes: Key Regulators of Neuroinflammation

(2016) Emanuela Colombo et al.   TRENDS IN IMMUNOLOGY

Mesenchymal stem cells and immunomodulation: current status and future prospects

(2016) F Gao et al.   Cell Death & Disease

Alternative source of stem cells derived from human periodontal ligament: a new treatment for experimental autoimmune encephalomyelitis

(2016) Oriana Trubiani et al.   Stem Cell Research & Therapy

Pluripotent Nontumorigenic Adipose Tissue-Derived Muse Cells have Immunomodulatory Capacity Mediated by Transforming Growth Factor-β1

(2016) María L. Gimeno et al.   Stem Cells Translational Medicine

Gingival Mesenchymal Stem/Progenitor Cells: A Unique Tissue Engineering Gem

(2016) Karim M. Fawzy El-Sayed et al.   Stem Cells International

Protection by Neuroglobin Expression in Brain Pathologies

(2016) Eliana Baez et al.   Frontiers in Neurology

Neuroglobin in Breast Cancer Cells: Effect of Hypoxia and Oxidative Stress on Protein Level, Localization, and Anti-Apoptotic Function

(2016) Marco Fiocchetti et al.   PLoS One

The complex contribution of chemokines to neuroinflammation: switching from beneficial to detrimental effects

(2015) Ophélia Le Thuc et al.   Annals of the New York Academy of Sciences

Conditioned medium from the stem cells of human dental pulp improves cognitive function in a mouse model of Alzheimer’s disease

(2015) Tsuneyuki Mita et al.   BEHAVIOURAL BRAIN RESEARCH

The contribution of astrocytes and microglia to traumatic brain injury

(2015) Ila P Karve et al.   BRITISH JOURNAL OF PHARMACOLOGY

Role for the PI3K/Akt/Nrf2 signaling pathway in the protective effects of carnosic acid against methylglyoxal-induced neurotoxicity in SH-SY5Y neuroblastoma cells

(2015) Marcos Roberto de Oliveira et al.   CHEMICO-BIOLOGICAL INTERACTIONS

CXCL8 as a Potential Therapeutic Target for HIV-Associated Neurocognitive Disorders

(2015) Manmeet K. Mamik et al.   CURRENT DRUG TARGETS

Negative regulation of the inflammasome: keeping inflammation under control

(2015) Gustavo Pedraza-Alva et al.   IMMUNOLOGICAL REVIEWS

Nanoalumina induces apoptosis by impairing antioxidant enzyme systems in human hepatocarcinoma cells

(2015) Daoud Daoud Ali et al.   International Journal of Nanomedicine

Paracrine Factors Secreted by MSCs Promote Astrocyte Survival Associated With GFAP Downregulation After Ischemic Stroke via p38 MAPK and JNK

(2015) Weiyi Huang et al.   JOURNAL OF CELLULAR PHYSIOLOGY

Dental follicle mesenchymal stem cell administration ameliorates muscle weakness in MuSK-immunized mice

(2015) Canan Ulusoy et al.   Journal of Neuroinflammation

Comparison of the effects of human dental pulp stem cells and human bone marrow-derived mesenchymal stem cells on ischemic human astrocytes in vitro

(2015) Miyeoun Song et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Mesenchymal stem cell–conditioned medium prevents radiation-induced liver injury by inhibiting inflammation and protecting sinusoidal endothelial cells

(2015) Yi-Xing Chen et al.   JOURNAL OF RADIATION RESEARCH

Roles of Neuroglobin Binding to Mitochondrial Complex III Subunit Cytochrome c1 in Oxygen-Glucose Deprivation-Induced Neurotoxicity in Primary Neurons

(2015) Zhanyang Yu et al.   MOLECULAR NEUROBIOLOGY

Neuroprotective effect of interleukin-6 regulation of voltage-gated Na+ channels of cortical neurons is time- and dose-dependent

(2015) Wei-qiang Chen et al.   Neural Regeneration Research

Human umbilical cord mesenchymal stem cells promote peripheral nerve repair via paracrine mechanisms

(2015) Yu Wang et al.   Neural Regeneration Research

TNF and its receptors in the CNS: The essential, the desirable and the deleterious effects

(2015) L. Probert   NEUROSCIENCE

Control of autoimmune CNS inflammation by astrocytes

(2015) Veit Rothhammer et al.   Seminars in Immunopathology

Astrocytes Control Synapse Formation, Function, and Elimination

(2015) Won-Suk Chung et al.   Cold Spring Harbor Perspectives in Biology

Astrocytic metabolic and inflammatory changes as a function of age

(2014) Tianyi Jiang et al.   AGING CELL

Autophagy plays a protective role during zVAD-induced necrotic cell death

(2014) You-Tong Wu et al.   Autophagy

Astrocytic gap junctional networks suppress cellular damage in an in vitro model of ischemia

(2014) Takanori Shinotsuka et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Overexpressing neuroglobin improves functional recovery by inhibiting neuronal apoptosis after spinal cord injury

(2014) Wen-Bin Lan et al.   BRAIN RESEARCH

Botanical Drug Puerarin Coordinates with Nerve Growth Factor in the Regulation of Neuronal Survival and Neuritogenesis via Activating ERK1/2 and PI3K/Akt Signaling Pathways in the Neurite Extension Process

(2014) Jia Zhao et al.   CNS Neuroscience & Therapeutics

Cerebral regulatory T cells restrain microglia/macrophage-mediated inflammatory responses via IL-10

(2014) Luokun Xie et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Neuroglobin mitigates mitochondrial impairments induced by acute inhalation of combustion smoke in the mouse brain

(2014) Falih Murat Gorgun et al.   INHALATION TOXICOLOGY

Functional Characterization of 5-Oxoproline Transport via SLC16A1/MCT1

(2014) Shotaro Sasaki et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Neuroimmune regulation of microglial activity involved in neuroinflammation and neurodegenerative diseases

(2014) Hugo González et al.   JOURNAL OF NEUROIMMUNOLOGY

Echinochrome A Increases Mitochondrial Mass and Function by Modulating Mitochondrial Biogenesis Regulatory Genes

(2014) Seung Jeong et al.   Marine Drugs

Conditioned medium of human adipose-derived mesenchymal stem cells mediates protection in neurons following glutamate excitotoxicity by regulating energy metabolism and GAP-43 expression

(2014) Peng Hao et al.   METABOLIC BRAIN DISEASE

Disturbed mitochondrial dynamics and neurodegenerative disorders

(2014) Florence Burté et al.   Nature Reviews Neurology

The deadly connection between endoplasmic reticulum, Ca2+, protein synthesis, and the endoplasmic reticulum stress response in malignant glioma cells

(2014) Guyla G. Johnson et al.   NEURO-ONCOLOGY

Neuroglobin overexpression improves sensorimotor outcomes in a mouse model of traumatic brain injury

(2014) Jordan M. Taylor et al.   NEUROSCIENCE LETTERS

PDGF-BB Protects Mitochondria from Rotenone in T98G Cells

(2014) Ricardo Cabezas et al.   NEUROTOXICITY RESEARCH

Paracrine Effect of Mesenchymal Stem Cells Derived from Human Adipose Tissue in Bone Regeneration

(2014) Itali Linero et al.   PLoS One

Neuroglobin involvement in visual pathways through the optic nerve

(2013) Christophe Lechauve et al.   BIOCHIMICA ET BIOPHYSICA ACTA-PROTEINS AND PROTEOMICS

Proteomic techniques for characterisation of mesenchymal stem cell secretome

(2013) Helena Kupcova Skalnikova   BIOCHIMIE

Comparison of mesenchymal stromal cells from human bone marrow and adipose tissue for the treatment of spinal cord injury

(2013) Zhilai Zhou et al.   CYTOTHERAPY

Paracrine factors of human mesenchymal stem cells increase wound closure and reduce reactive oxygen species production in a traumatic brain injury in vitro model

(2013) D Torrente et al.   HUMAN & EXPERIMENTAL TOXICOLOGY

A Defined Methodology for Reliable Quantification of Western Blot Data

(2013) Sean C. Taylor et al.   MOLECULAR BIOTECHNOLOGY

Dominant optic atrophy, OPA1, and mitochondrial quality control: understanding mitochondrial network dynamics

(2013) Marcel V Alavi et al.   Molecular Neurodegeneration

Genistein alleviates the mitochondria-targeted DNA damage induced by β-amyloid peptides 25–35 in C6 glioma cells

(2013) Wei-wei Ma et al.   NEUROCHEMICAL RESEARCH

Mitochondrial Mechanisms of Neuroglobin’s Neuroprotection

(2013) Zhanyang Yu et al.   Oxidative Medicine and Cellular Longevity

Therapeutic Potential of Mesenchymal Stromal Cells and MSC Conditioned Medium in Amyotrophic Lateral Sclerosis (ALS) - In Vitro Evidence from Primary Motor Neuron Cultures, NSC-34 Cells, Astrocytes and Microglia

(2013) Hui Sun et al.   PLoS One

Neuroglobin upregulation induced by 17β-estradiol sequesters cytocrome c in the mitochondria preventing H2O2-induced apoptosis of neuroblastoma cells

(2013) E De Marinis et al.   Cell Death & Disease

Mitochondrial morphology in mitophagy and macroautophagy

(2012) Ligia C. Gomes et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Recent advances into the understanding of mitochondrial fission

(2012) Kirstin Elgass et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Neuroglobin-overexpression reduces traumatic brain lesion size in mice

(2012) Song Zhao et al.   BMC NEUROSCIENCE

Mesenchymal stem cells protect CNS neurons against glutamate excitotoxicity by inhibiting glutamate receptor expression and function

(2012) A. Voulgari-Kokota et al.   EXPERIMENTAL NEUROLOGY

Interleukin-6, a Major Cytokine in the Central Nervous System

(2012) María Erta et al.   International Journal of Biological Sciences

Neuroglobin, a Novel Target for Endogenous Neuroprotection against Stroke and Neurodegenerative Disorders

(2012) Zhanyang Yu et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

Mitochondrial distribution of neuroglobin and its response to oxygen–glucose deprivation in primary-cultured mouse cortical neurons

(2012) Z. Yu et al.   NEUROSCIENCE

Interactions between vascular endothelial growth factor and neuroglobin

(2012) Kunlin Jin et al.   NEUROSCIENCE LETTERS

Mitochondrial elongation during autophagy

(2011) Ligia C. Gomes et al.   Autophagy

Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner

(2011) Janel E. Le Belle et al.   Cell Stem Cell

Optic atrophy 1 is an A-kinase anchoring protein on lipid droplets that mediates adrenergic control of lipolysis

(2011) Guillaume Pidoux et al.   EMBO JOURNAL

GDNF modifies reactive astrogliosis allowing robust axonal regeneration through Schwann cell-seeded guidance channels after spinal cord injury

(2011) Ling-Xiao Deng et al.   EXPERIMENTAL NEUROLOGY

Cytokines and brain excitability

(2011) Michael A. Galic et al.   FRONTIERS IN NEUROENDOCRINOLOGY

Therapeutic potential of a distinct population of human amniotic fluid mesenchymal stem cells and their secreted molecules in mice with acute hepatic failure

(2011) Dimitra S Zagoura et al.   GUT

Nrf2 regulates NGF mRNA induction by carnosic acid in T98G glioblastoma cells and normal human astrocytes

(2011) Junsei Mimura et al.   JOURNAL OF BIOCHEMISTRY

DHA inhibits ER Ca2+ release and ER stress in astrocytes following in vitro ischemia

(2011) Gulnaz Begum et al.   JOURNAL OF NEUROCHEMISTRY

Calcium signalling in astroglia

(2011) Alexei Verkhratsky et al.   MOLECULAR AND CELLULAR ENDOCRINOLOGY

BDNF Promotes EGF-Induced Proliferation and Migration of Human Fetal Neural Stem/Progenitor Cells via the PI3K/Akt Pathway

(2011) Qi Zhang et al.   MOLECULES

During autophagy mitochondria elongate, are spared from degradation and sustain cell viability

(2011) Ligia C. Gomes et al.   NATURE CELL BIOLOGY

Endoplasmic Reticulum Calcium Release Engages Bax Translocation in Cortical Astrocytes

(2011) A. P. Morales et al.   NEUROCHEMICAL RESEARCH

Acquisition of Chemoresistance in Gliomas Is Associated with Increased Mitochondrial Coupling and Decreased ROS Production

(2011) Claudia R. Oliva et al.   PLoS One

Dynamic regulation of mitochondrial fission through modification of the dynamin-related protein Drp1

(2010) Chuang-Rung Chang et al.   Annals of the New York Academy of Sciences

Ca2+ sources for the exocytotic release of glutamate from astrocytes

(2010) Vladimir Parpura et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Inhibition of Drp1-dependent mitochondrial fragmentation and apoptosis by a polypeptide antagonist of calcineurin

(2010) G M Cereghetti et al.   CELL DEATH AND DIFFERENTIATION

Neuroprotection signaling pathway of nerve growth factor and brain-derived neurotrophic factor against staurosporine induced apoptosis in hippocampal H19-7 cells

(2010) Truong LX Nguyen et al.   EXPERIMENTAL AND MOLECULAR MEDICINE

OPA1 links human mitochondrial genome maintenance to mtDNA replication and distribution

(2010) G. Elachouri et al.   GENOME RESEARCH

Inflammation in neurodegenerative diseases

(2010) Sandra Amor et al.   IMMUNOLOGY

Mitochondrial Protection Attenuates Inflammation-Induced Impairment of Neurogenesis In Vitro and In Vivo

(2010) L. A. Voloboueva et al.   JOURNAL OF NEUROSCIENCE

Overexpressing GRP78 influences Ca2+ handling and function of mitochondria in astrocytes after ischemia-like stress

(2010) Yi-Bing Ouyang et al.   MITOCHONDRION

Aberrant mitochondrial fission in neurons induced by protein kinase Cδ under oxidative stress conditions in vivo

(2010) Xin Qi et al.   MOLECULAR BIOLOGY OF THE CELL

Reactive astrocytosis-induced perturbation of synaptic homeostasis is restored by nerve growth factor

(2010) Giovanni Cirillo et al.   NEUROBIOLOGY OF DISEASE

Functions of astrocytes and their potential as therapeutic targets

(2010) Harold K. Kimelberg et al.   Neurotherapeutics

Neuroglobin, cytoglobin, and myoglobin contribute to hypoxia adaptation of the subterranean mole rat Spalax

(2010) A. Avivi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Quantifying Western blots: Pitfalls of densitometry

(2009) Max Gassmann et al.   ELECTROPHORESIS

SLP-2 is required for stress-induced mitochondrial hyperfusion

(2009) Daniel Tondera et al.   EMBO JOURNAL

Parkinson’s disease and mitochondrial complex I: a perspective on the Ndi1 therapy

(2009) Mathieu Marella et al.   JOURNAL OF BIOENERGETICS AND BIOMEMBRANES

Human bone marrow-derived mesenchymal stem cells secrete brain-derived neurotrophic factor which promotes neuronal survival in vitro

(2009) Alastair Wilkins et al.   Stem Cell Research

(−)-Epigallocatechin gallate induces Nrf2-mediated antioxidant enzyme expression via activation of PI3K and ERK in human mammary epithelial cells

(2008) Hye-Kyung Na et al.   ARCHIVES OF BIOCHEMISTRY AND BIOPHYSICS

The Role of Autophagy in Mammalian Development: Cell Makeover Rather than Cell Death

(2008) Francesco Cecconi et al.   DEVELOPMENTAL CELL

CXCL12 (SDF-1α) suppresses ongoing experimental autoimmune encephalomyelitis by selecting antigen-specific regulatory T cells

(2008) Moran Meiron et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Multiple protective activities of neuroglobin in cultured neuronal cells exposed to hypoxia re-oxygenation injury

(2008) Thi Thuy Hong Duong et al.   JOURNAL OF NEUROCHEMISTRY

Mitochondria Modulate Ca2+-Dependent Glutamate Release from Rat Cortical Astrocytes

(2008) R. C. Reyes et al.   JOURNAL OF NEUROSCIENCE

Mitochondrial Dysfunction in SOD1G93A-Bearing Astrocytes Promotes Motor Neuron Degeneration: Prevention by Mitochondrial-Targeted Antioxidants

(2008) P. Cassina et al.   JOURNAL OF NEUROSCIENCE

Effects of neuroglobin overexpression on mitochondrial function and oxidative stress following hypoxia/reoxygenation in cultured neurons

(2008) Jianxiang Liu et al.   JOURNAL OF NEUROSCIENCE RESEARCH

Inhibition of peripheral TNF can block the malaise associated with CNS inflammatory diseases

(2008) Y. Jiang et al.   NEUROBIOLOGY OF DISEASE

IFATS Collection: The Conditioned Media of Adipose Stromal Cells Protect Against Hypoxia-Ischemia-Induced Brain Damage in Neonatal Rats

(2008) Xing Wei et al.   STEM CELLS

The role of inflammation in CNS injury and disease

(2006) Sian-Marie Lucas et al.   BRITISH JOURNAL OF PHARMACOLOGY