Bone Marrow-Derived CD4+ T Cells Are Depleted in Simian Immunodeficiency Virus-Infected Macaques and Contribute to the Size of the Replication-Competent Reservoir

Liver macrophage-associated inflammation correlates with SIV burden and is substantially reduced following cART

(2018) Bridget S. Fisher et al.   PLoS Pathogens

CTLA-4 + PD-1 − Memory CD4 + T Cells Critically Contribute to Viral Persistence in Antiretroviral Therapy-Suppressed, SIV-Infected Rhesus Macaques

(2017) Colleen S. McGary et al.   IMMUNITY

Paradoxical myeloid-derived suppressor cell reduction in the bone marrow of SIV chronically infected macaques

(2017) Yongjun Sui et al.   PLoS Pathogens

Determinants of a Low CD4/CD8 Ratio in HIV-1–Infected Individuals Despite Long-term Viral Suppression

(2016) Fabienne Caby et al.   CLINICAL INFECTIOUS DISEASES

PD-1+ and follicular helper T cells are responsible for persistent HIV-1 transcription in treated aviremic individuals

(2016) Riddhima Banga et al.   NATURE MEDICINE

CD4+ T Cells Expressing PD-1, TIGIT and LAG-3 Contribute to HIV Persistence during ART

(2016) Rémi Fromentin et al.   PLoS Pathogens

Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques

(2015) Luca Micci et al.   JOURNAL OF CLINICAL INVESTIGATION

CD4:CD8 ratio as a frontier marker for clinical outcome, immune dysfunction and viral reservoir size in virologically suppressed HIV-positive patients

(2015) Wei Lu et al.   Journal of the International AIDS Society

Selective Loss of Early Differentiated, Highly Functional PD1high CD4 T Cells with HIV Progression

(2015) Robert M. Paris et al.   PLoS One

Human Bone Marrow Hosts Polyfunctional Memory CD4+ and CD8+ T Cells with Close Contact to IL-15-Producing Cells

(2011) D. Herndler-Brandstetter et al.   JOURNAL OF IMMUNOLOGY

The impact of aging on memory T cell phenotype and function in the human bone marrow

(2011) Dietmar Herndler-Brandstetter et al.   JOURNAL OF LEUKOCYTE BIOLOGY

HIV Infection, Inflammation, Immunosenescence, and Aging

(2010) Steven G. Deeks   Annual Review of Medicine

HIV reservoir size and persistence are driven by T cell survival and homeostatic proliferation

(2009) Nicolas Chomont et al.   NATURE MEDICINE

Changes in the Risk of Death After HIV Seroconversion Compared With Mortality in the General Population

(2008) Krishnan Bhaskaran   JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION

Life and death in the cART era

(2008) David A Cooper   LANCET