Determinants of a Low CD4/CD8 Ratio in HIV-1–Infected Individuals Despite Long-term Viral Suppression

Residual immune activation in combined antiretroviral therapy-treated patients with maximally suppressed viremia

(2016) Amélie Guihot et al.   AIDS

CD8 T-Cell Expansion and Inflammation Linked to CMV Coinfection in ART-treated HIV Infection

(2015) Michael L. Freeman et al.   CLINICAL INFECTIOUS DISEASES

Changes in Inflammation and Immune Activation With Atazanavir-, Raltegravir-, Darunavir-Based Initial Antiviral Therapy: ACTG 5260s

(2015) Theodoros Kelesidis et al.   CLINICAL INFECTIOUS DISEASES

CD4/CD8 ratio normalisation and non-AIDS-related events in individuals with HIV who achieve viral load suppression with antiretroviral therapy: an observational cohort study

(2015) Cristina Mussini et al.   Lancet HIV

Immune resilience in HIV-infected individuals seronegative for cytomegalovirus

(2014) Lisa Barrett et al.   AIDS

Significant Reduction in HIV Virologic Failure During a 15-Year Period in a Setting With Free Healthcare Access

(2014) C. Delaugerre et al.   CLINICAL INFECTIOUS DISEASES

Factors Associated With CD8+ T-Cell Activation in HIV-1–Infected Patients on Long-term Antiretroviral Therapy

(2014) Lu Zheng et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Multiparametric Bioinformatics Distinguish the CD4/CD8 Ratio as a Suitable Laboratory Predictor of Combined T Cell Pathogenesis in HIV Infection

(2014) M. Buggert et al.   JOURNAL OF IMMUNOLOGY

Cytomegalovirus Coinfection Is Associated With an Increased Risk of Severe Non–AIDS-Defining Events in a Large Cohort of HIV-Infected Patients

(2014) Miriam Lichtner et al.   JOURNAL OF INFECTIOUS DISEASES

Letermovir for Cytomegalovirus Prophylaxis in Hematopoietic-Cell Transplantation

(2014) Roy F. Chemaly et al.   NEW ENGLAND JOURNAL OF MEDICINE

Increased Risk of Serious Non-AIDS-Related Events in HIV-Infected Subjects on Antiretroviral Therapy Associated with a Low CD4/CD8 Ratio

(2014) Sergio Serrano-Villar et al.   PLoS One

Tobacco Smoking Increases Immune Activation and Impairs T-Cell Function in HIV Infected Patients on Antiretrovirals: A Cross-Sectional Pilot Study

(2014) Ranjini Valiathan et al.   PLoS One

HIV-Infected Individuals with Low CD4/CD8 Ratio despite Effective Antiretroviral Therapy Exhibit Altered T Cell Subsets, Heightened CD8+ T Cell Activation, and Increased Risk of Non-AIDS Morbidity and Mortality

(2014) Sergio Serrano-Villar et al.   PLoS Pathogens

Severity of Cardiovascular Disease Outcomes Among Patients With HIV Is Related to Markers of Inflammation and Coagulation

(2014) Anna D. Nordell et al.   Journal of the American Heart Association

The CD4/CD8 ratio as a marker T-cell activation, senescence and activation/exhaustion in treated HIV-infected children and young adults

(2013) Talía Sainz et al.   AIDS

The CD4:CD8 ratio is associated with markers of age-associated disease in virally suppressed HIV-infected patients with immunological recovery

(2013) S Serrano-Villar et al.   HIV MEDICINE

Associations of Inflammatory Markers With AIDS and Non-AIDS Clinical Events After Initiation of Antiretroviral Therapy

(2013) Grace A. McComsey et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

Predictors of CD4:CD8 Ratio Normalization and Its Effect on Health Outcomes in the Era of Combination Antiretroviral Therapy

(2013) Victor Leung et al.   PLoS One

The inverted CD4/CD8 ratio and associated parameters in 66-year-old individuals: the Swedish HEXA immune study

(2012) J. Strindhall et al.   AGE

Circulating interleukin-6 levels correlate with residual HIV viraemia and markers of immune dysfunction in treatment-controlled HIV-infected patients

(2012) Jean-Philippe Bastard et al.   ANTIVIRAL THERAPY

Higher Immunoglobulin G Antibody Levels Against Cytomegalovirus Are Associated With Incident Ischemic Heart Disease in the Population-Based EPIC-Norfolk Cohort

(2012) E. Gkrania-Klotsas et al.   JOURNAL OF INFECTIOUS DISEASES

Cytomegalovirus and Immunological Aging: The Real Driver of HIV and Heart Disease?

(2012) A. E. Aiello et al.   JOURNAL OF INFECTIOUS DISEASES

T-Cell Phenotypes, Apoptosis and Inflammation in HIV+ Patients on Virologically Effective cART with Early Atherosclerosis

(2012) Esther Merlini et al.   PLoS One

HIV disease progression despite suppression of viral replication is associated with exhaustion of lymphopoiesis

(2011) D. Sauce et al.   BLOOD

Valganciclovir Reduces T Cell Activation in HIV-Infected Individuals With Incomplete CD4+ T Cell Recovery on Antiretroviral Therapy

(2011) Peter W. Hunt et al.   JOURNAL OF INFECTIOUS DISEASES

Clinical Predictors of Immune Reconstitution following Combination Antiretroviral Therapy in Patients from the Australian HIV Observational Database

(2011) Reena Rajasuriar et al.   PLoS One

Immune reconstitution after a decade of combined antiretroviral therapies for human immunodeficiency virus

(2011) Amélie Guihot et al.   TRENDS IN IMMUNOLOGY

Immune and virological benefits of 10 years of permanent viral control with antiretroviral therapy

(2010) Amélie Guihot et al.   AIDS

Increased prevalence of subclinical coronary atherosclerosis detected by coronary computed tomography angiography in HIV-infected men

(2009) Janet Lo et al.   AIDS

Poor Baseline Immune Function Predicts an Incomplete Immune Response to Combination Antiretroviral Treatment Despite Sustained Viral Suppression

(2009) Kathleen Falster et al.   JAIDS-JOURNAL OF ACQUIRED IMMUNE DEFICIENCY SYNDROMES

The immune risk profile is associated with age and gender: findings from three Swedish population studies of individuals 20–100 years of age

(2008) Anders Wikby et al.   BIOGERONTOLOGY