Small-fiber neuropathy: Expanding the clinical pain universe

Sudomotor function testing by electrochemical skin conductance: does it really measure sudomotor function?

(2018) Sharika Rajan et al.   CLINICAL AUTONOMIC RESEARCH

A comparison between the neural correlates of laser and electric pain stimulation and their modulation by expectation

(2018) E.J. Hird et al.   JOURNAL OF NEUROSCIENCE METHODS

Atypical changes in DRG neuron excitability and complex pain phenotype associated with a Nav1.7 mutation that massively hyperpolarizes activation

(2018) Jianying Huang et al.   Scientific Reports

Associated conditions in small fiber neuropathy - a large cohort study and review of the literature

(2017) B. T. A. de Greef et al.   EUROPEAN JOURNAL OF NEUROLOGY

Gain-of-function mutation of a voltage-gated sodium channel NaV1.7 associated with peripheral pain and impaired limb development

(2017) Brian S. Tanaka et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sodium channel NaV1.9 mutations associated with insensitivity to pain dampen neuronal excitability

(2017) Jianying Huang et al.   JOURNAL OF CLINICAL INVESTIGATION

Initial Development and Validation of a Patient-Reported Symptom Survey for Small-Fiber Polyneuropathy

(2017) Roi Treister et al.   JOURNAL OF PAIN

Safety and efficacy of a Nav1.7 selective sodium channel blocker in patients with trigeminal neuralgia: a double-blind, placebo-controlled, randomised withdrawal phase 2a trial

(2017) Joanna M Zakrzewska et al.   LANCET NEUROLOGY

New technologies for the assessment of neuropathies

(2017) Roberto Gasparotti et al.   Nature Reviews Neurology

Pain insensitivity: distal S6-segment mutations in NaV1.9 emerge as critical hotspot

(2017) Margaret K. King et al.   NEUROGENETICS

Early skin denervation in hereditary and iatrogenic transthyretin amyloid neuropathy

(2017) Teruaki Masuda et al.   NEUROLOGY

Pain-related evoked potentials after intraepidermal electrical stimulation to Aδ and C fibers in patients with neuropathic pain

(2017) Shigeki Omori et al.   NEUROSCIENCE RESEARCH

Sodium channels in pain disorders

(2017) Sulayman D. Dib-Hajj et al.   PAIN

Biomarkers of neuropathic pain in skin nerve degeneration neuropathy

(2017) Shao-Wei Wu et al.   PAIN

SUDOSCAN, an effective tool for screening chronic kidney disease in patients with type 2 diabetes

(2017) Fei Mao et al.   Experimental and Therapeutic Medicine

Epidermal Nerve Fiber Quantification in Patients With Erythromelalgia

(2017) William G. Mantyh et al.   JAMA Dermatology

Use of Corneal Confocal Microscopy to Detect Corneal Nerve Loss and Increased Dendritic Cells in Patients With Multiple Sclerosis

(2017) Gulfidan Bitirgen et al.   JAMA Ophthalmology

Congenital insensitivity to pain: Fracturing without apparent skeletal pathobiology caused by an autosomal dominant, second mutation in SCN11A encoding voltage-gated sodium channel 1.9

(2016) Voraluck Phatarakijnirund et al.   BONE

Inherited erythromelalgia due to mutations inSCN9A:natural history, clinical phenotype and somatosensory profile

(2016) Aoibhinn McDonnell et al.   BRAIN

First European consensus for diagnosis, management, and treatment of transthyretin familial amyloid polyneuropathy

(2016) David Adams et al.   CURRENT OPINION IN NEUROLOGY

Amyotrophic lateral sclerosis causes small fiber pathology

(2016) E. Dalla Bella et al.   EUROPEAN JOURNAL OF NEUROLOGY

Painful small fiber neuropathy with gastroparesis: A new phenotype with a novel mutation in the SCN10A gene

(2016) Ron Dabby et al.   JOURNAL OF CLINICAL NEUROSCIENCE

Diagnostic value of blood tests for occult causes of initially idiopathic small-fiber polyneuropathy

(2016) Magdalena Lang et al.   JOURNAL OF NEUROLOGY

Familial gain-of-function Na v 1.9 mutation in a painful channelopathy

(2016) Chongyang Han et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Nav1.7-A1632G Mutation from a Family with Inherited Erythromelalgia: Enhanced Firing of Dorsal Root Ganglia Neurons Evoked by Thermal Stimuli

(2016) Y. Yang et al.   JOURNAL OF NEUROSCIENCE

Skin biopsy in assessing meralgia paresthetica

(2016) Arada Wongmek et al.   MUSCLE & NERVE

Small fiber neuropathy is a common feature of Ehlers-Danlos syndromes

(2016) Daniele Cazzato et al.   NEUROLOGY

Non-motor involvement in amyotrophic lateral sclerosis: new insight from nerve and vessel analysis in skin biopsy

(2016) M. Nolano et al.   NEUROPATHOLOGY AND APPLIED NEUROBIOLOGY

Reduced intraepidermal nerve fiber density in patients with REM sleep behavior disorder

(2016) Wiebke Schrempf et al.   PARKINSONISM & RELATED DISORDERS

Evidence for small fiber neuropathy in early Parkinson's disease

(2016) Peter J. Podgorny et al.   PARKINSONISM & RELATED DISORDERS

Small Fiber Neuropathy in Children: Two Case Reports Illustrating the Importance of Recognition

(2016) J. G. J. Hoeijmakers et al.   PEDIATRICS

No Fabry Disease in Patients Presenting with Isolated Small Fiber Neuropathy

(2016) Bianca T. A. de Greef et al.   PLoS One

Infantile Pain Episodes Associated with Novel Nav1.9 Mutations in Familial Episodic Pain Syndrome in Japanese Families

(2016) Hiroko Okuda et al.   PLoS One

Pharmacological reversal of a pain phenotype in iPSC-derived sensory neurons and patients with inherited erythromelalgia

(2016) Lishuang Cao et al.   Science Translational Medicine

Sodium Channels, Mitochondria, and Axonal Degeneration in Peripheral Neuropathy

(2016) Anna-Karin Persson et al.   TRENDS IN MOLECULAR MEDICINE

Longitudinal Assessment of Small Fiber Neuropathy

(2016) Mohammad A. Khoshnoodi et al.   JAMA Neurology

Pharmacotherapy for Pain in a Family With Inherited Erythromelalgia Guided by Genomic Analysis and Functional Profiling

(2016) Paul Geha et al.   JAMA Neurology

Pathological nociceptors in two patients with erythromelalgia-like symptoms and rare genetic Nav 1.9 variants

(2016) Inge P. Kleggetveit et al.   Brain and Behavior

Accuracy of a Rapid and Non-Invasive Method for the Assessment of Small Fiber Neuropathy Based on Measurement of Electrochemical Skin Conductances

(2016) Lyse Bordier et al.   Frontiers in Endocrinology

Subtype-Selective Small Molecule Inhibitors Reveal a Fundamental Role for Nav1.7 in Nociceptor Electrogenesis, Axonal Conduction and Presynaptic Release

(2016) Aristos J. Alexandrou et al.   PLoS One

SCN10A Mutation in a Patient with Erythromelalgia Enhances C-Fiber Activity Dependent Slowing

(2016) Andreas M. Kist et al.   PLoS One

p.L1612P, a Novel Voltage-gated Sodium Channel Nav1.7 Mutation Inducing a Cold Sensitive Paroxysmal Extreme Pain Disorder

(2015) Marc R. Suter et al.   ANESTHESIOLOGY

Microneurographic recording from unmyelinated nerve fibers in neurological disorders: An update

(2015) V. Donadio et al.   CLINICAL NEUROPHYSIOLOGY

Stimulated skin wrinkling as an indicator of limb sympathetic function

(2015) Einar P.V. Wilder-Smith   CLINICAL NEUROPHYSIOLOGY

Neuropathic pain assessment

(2015) Tina Mainka et al.   Current Opinion in Anesthesiology

Normative Values for Corneal Nerve Morphology Assessed Using Corneal Confocal Microscopy: A Multinational Normative Data Set

(2015) Mitra Tavakoli et al.   DIABETES CARE

Neuropathic Pain due to Small Fiber Neuropathy in Aging: Current Management and Future Prospects

(2015) Brigitte A. Brouwer et al.   DRUGS & AGING

A multi-center, multinational age- and gender-adjusted normative dataset for immunofluorescent intraepidermal nerve fiber density at the distal leg

(2015) V. Provitera et al.   EUROPEAN JOURNAL OF NEUROLOGY

Quality of life in polyneuropathy: association with biomarkers of small fiber impairment

(2015) Meng-Ting Lin et al.   Health and Quality of Life Outcomes

Bilateral congenital corneal anesthesia in a patient with SCN9A mutation, confirmed primary erythromelalgia, and paroxysmal extreme pain disorder

(2015) David Ta Kim et al.   JOURNAL OF AAPOS

Erythromelalgia Mutation Q875E Stabilizes the Activated State of Sodium Channel Nav1.7

(2015) Theresa Stadler et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

CIDP variants in diabetes: measuring treatment response with a small nerve fiber test

(2015) Marie-Laure Névoret et al.   JOURNAL OF DIABETES AND ITS COMPLICATIONS

Short-lasting unilateral neuralgiform headache attacks with ispilateral facial flushing is a new variant of paroxysmal extreme pain disorder

(2015) Noboru Imai et al.   JOURNAL OF HEADACHE AND PAIN

Small-fibre neuropathy related to bulbar and spinal-onset in patients with ALS

(2015) A. Truini et al.   JOURNAL OF NEUROLOGY

Novel SCN9A Mutations Underlying Extreme Pain Phenotypes: Unexpected Electrophysiological and Clinical Phenotype Correlations

(2015) E. C. Emery et al.   JOURNAL OF NEUROSCIENCE

Pruritus: An underrecognized symptom of small-fiber neuropathies

(2015) Emilie Brenaut et al.   JOURNAL OF THE AMERICAN ACADEMY OF DERMATOLOGY

SCN9A-associated congenital insensitivity to pain and anosmia in an Irish patient

(2015) Petya Bogdanova-Mihaylova et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Improving assessment in small fiber neuropathy

(2015) Brigitte A. Brouwer et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Pharmacotherapy for neuropathic pain in adults: a systematic review and meta-analysis

(2015) Nanna B Finnerup et al.   LANCET NEUROLOGY

Sodium Channel Nav1.7 in Vascular Myocytes, Endothelium, and Innervating Axons in Human Skin

(2015) Frank L Rice et al.   Molecular Pain

Small-nerve-fiber pathology in critical illness documented by serial skin biopsies

(2015) Miroslav Skorna et al.   MUSCLE & NERVE

Optimizing temperature threshold testing in small-fiber neuropathy

(2015) Mayienne Bakkers et al.   MUSCLE & NERVE

Contact heat evoked potentials: Normal values and use in small-fiber neuropathy

(2015) Vera Lagerburg et al.   MUSCLE & NERVE

NaV1.9: a sodium channel linked to human pain

(2015) Sulayman D. Dib-Hajj et al.   NATURE REVIEWS NEUROSCIENCE

Role of combined B-mode and Doppler sonography in evaluating neurolymphomatosis

(2015) Joy Vijayan et al.   NEUROLOGY

Side and time variability of intraepidermal nerve fiber density

(2015) G. Lauria et al.   NEUROLOGY

Advances in diagnostics and outcome measures in peripheral neuropathies

(2015) Ingemar S.J. Merkies et al.   NEUROSCIENCE LETTERS

Painful peripheral neuropathy and sodium channel mutations

(2015) Janneke G.J. Hoeijmakers et al.   NEUROSCIENCE LETTERS

Specific changes in conduction velocity recovery cycles of single nociceptors in a patient with erythromelalgia with the I848T gain-of-function mutation of Nav1.7

(2015) Barbara Namer et al.   PAIN

Imaging signatures of altered brain responses in small-fiber neuropathy

(2015) Paul-Chen Hsieh et al.   PAIN

Small fiber neuropathy in Parkinson's disease: A clinical, pathological and corneal confocal microscopy study

(2015) Lewis Kass-Iliyya et al.   PARKINSONISM & RELATED DISORDERS

Peripheral Nerve Ultrasound in Small Fiber Polyneuropathy

(2015) Hamid Ebadi et al.   ULTRASOUND IN MEDICINE AND BIOLOGY

Cold-aggravated pain in humans caused by a hyperactive NaV1.9 channel mutant

(2015) Enrico Leipold et al.   Nature Communications

Supervised exercise improves cutaneous reinnervation capacity in metabolic syndrome patients

(2014) J. Robinson Singleton et al.   ANNALS OF NEUROLOGY

Gain-of-function mutations in sodium channel NaV1.9 in painful neuropathy

(2014) Jianying Huang et al.   BRAIN

Channelopathy: a novel mutation in theSCN9Agene causes insensitivity to pain and autonomic dysregulation

(2014) F. Bartholomew et al.   BRITISH JOURNAL OF DERMATOLOGY

Evaluation of nociceptive Aδ- and C-fiber dysfunction with lidocaine using intraepidermal electrical stimulation

(2014) Minori Kodaira et al.   CLINICAL NEUROPHYSIOLOGY

Corneal Confocal Microscopy Shows an Improvement in Small-Fiber Neuropathy in Subjects With Type 1 Diabetes on Continuous Subcutaneous Insulin Infusion Compared With Multiple Daily Injection: Table 1

(2014) Shazli Azmi et al.   DIABETES CARE

The diagnostic accuracy of Neuropad®for assessing large and small fibre diabetic neuropathy

(2014) G. Ponirakis et al.   DIABETIC MEDICINE

The phenotype of congenital insensitivity to pain due to the NaV1.9 variant p.L811P

(2014) Christopher Geoffrey Woods et al.   EUROPEAN JOURNAL OF HUMAN GENETICS

Reduction of Intraepidermal Nerve Fiber Density (IENFD) in the skin biopsies of patients with fibromyalgia: A controlled study

(2014) Michalis L. Kosmidis et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Painful neuropathies: the emerging role of sodium channelopathies

(2014) Brigitte A. Brouwer et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Sodium channel genes in pain-related disorders: phenotype–genotype associations and recommendations for clinical use

(2014) Stephen G Waxman et al.   LANCET NEUROLOGY

Neuropathic pruritus

(2014) Laurent Misery et al.   Nature Reviews Neurology

Intraepidermal nerve fiber density of healthy human

(2014) Yongdan Liu et al.   NEUROLOGICAL RESEARCH

Paroxysmal itch caused by gain-of-function Nav1.7 mutation

(2014) Grazia Devigili et al.   PAIN

Reduced intraepidermal nerve fiber density in patients with chronic ischemic pain in peripheral arterial disease

(2014) Eva Gröne et al.   PAIN

A gain-of-function voltage-gated sodium channel 1.8 mutation drives intense hyperexcitability of A- and C-fiber neurons

(2014) Sheldon R. Garrison et al.   PAIN

Painful micturition in a small child: an unusual clinical picture of paroxysmal extreme pain disorder

(2014) Anamarija Meglič et al.   PEDIATRIC NEPHROLOGY

A Novel Nonsense Mutation in SCN9A in a Moroccan Child With Congenital Insensitivity to Pain

(2014) Maria Mansouri et al.   PEDIATRIC NEUROLOGY

Channelopathies, painful neuropathy, and diabetes: which way does the causal arrow point?

(2014) Janneke G.J. Hoeijmakers et al.   TRENDS IN MOLECULAR MEDICINE

Health status, function, productivity, and costs among individuals with idiopathic painful peripheral neuropathy with small fiber involvement in the United States: results from a retrospective chart review and cross-sectional survey

(2014) Caroline Schaefer et al.   JOURNAL OF MEDICAL ECONOMICS

Gain-of-Function Mutations in SCN11A Cause Familial Episodic Pain

(2013) Xiang Yang Zhang et al.   AMERICAN JOURNAL OF HUMAN GENETICS

Physical Therapy Modalities and Rehabilitation Techniques in the Management of Neuropathic Pain

(2013) Gulseren Akyuz et al.   AMERICAN JOURNAL OF PHYSICAL MEDICINE & REHABILITATION

A new Nav1.7 mutation in an erythromelalgia patient

(2013) Mark Estacion et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Differential effect of D623N variant and wild-type Nav1.7 sodium channels on resting potential and interspike membrane potential of dorsal root ganglion neurons

(2013) Hye-Sook Ahn et al.   BRAIN RESEARCH

Sensory correlates of pain in peripheral neuropathies

(2013) Sophie Ng Wing Tin et al.   CLINICAL NEUROPHYSIOLOGY

Contact Heat-Evoked Potential Stimulation for the Evaluation of Small Nerve Fiber Function

(2013) Henri K. Parson et al.   Diabetes Technology & Therapeutics

Sudoscan, a Noninvasive Tool for Detecting Diabetic Small Fiber Neuropathy and Autonomic Dysfunction

(2013) Carolina M. Casellini et al.   Diabetes Technology & Therapeutics

The G1662S NaV1.8 mutation in small fibre neuropathy: impaired inactivation underlying DRG neuron hyperexcitability

(2013) C. Han et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Epidermal Nerve Fiber Length Density Estimation Using Global Spatial Sampling in Healthy Subjects and Neuropathy Patients

(2013) Páll Karlsson et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Small-Fiber Neuropathy Nav1.8 Mutation Shifts Activation to Hyperpolarized Potentials and Increases Excitability of Dorsal Root Ganglion Neurons

(2013) J. Huang et al.   JOURNAL OF NEUROSCIENCE

Temperature threshold testing: a systematic review

(2013) Mayienne Bakkers et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Small fibers, large impact: Quality of life in small-fiber neuropathy

(2013) Mayienne Bakkers et al.   MUSCLE & NERVE

An atypical case ofSCN9Amutation presenting with global motor delay and a severe pain disorder

(2013) Inge Anita Meijer et al.   MUSCLE & NERVE

Contribution of QSART to the diagnosis of small fiber neuropathy

(2013) Pariwat Thaisetthawatkul et al.   MUSCLE & NERVE

A de novo gain-of-function mutation in SCN11A causes loss of pain perception

(2013) Enrico Leipold et al.   NATURE GENETICS

Incidence and prevalence of small-fiber neuropathy: A survey in the Netherlands

(2013) M. J. H. Peters et al.   NEUROLOGY

Novel Mutations Mapping to the Fourth Sodium Channel Domain of Nav1.7 Result in Variable Clinical Manifestations of Primary Erythromelalgia

(2013) Roman Cregg et al.   NEUROMOLECULAR MEDICINE

Value of quantitative sensory testing in neurological and pain disorders: NeuPSIG consensus

(2013) Miroslav “Misha Backonja et al.   PAIN

A Novel Mutation in SCN9A in a Child With Congenital Insensitivity to Pain

(2013) Zamir Shorer et al.   PEDIATRIC NEUROLOGY

Evidence of Small-Fiber Polyneuropathy in Unexplained, Juvenile-Onset, Widespread Pain Syndromes

(2013) A. L. Oaklander et al.   PEDIATRICS

EMLA-Induced Skin Wrinkling for the Detection of Diabetic Neuropathy

(2013) Kay Wei Ping Ng et al.   Frontiers in Neurology

Comprehensive Chronic Pain Management: Improving Physical and Psychological Function (CME Multimedia Activity)

(2012) Bill H. McCarberg et al.   AMERICAN JOURNAL OF MEDICINE

Neuropathy-associated NaV1.7 variant I228M impairs integrity of dorsal root ganglion neuron axons

(2012) Anna-Karin Persson et al.   ANNALS OF NEUROLOGY

Functional profiles of SCN9A variants in dorsal root ganglion neurons and superior cervical ganglion neurons correlate with autonomic symptoms in small fibre neuropathy

(2012) Chongyang Han et al.   BRAIN

Small nerve fibres, small hands and small feet: a new syndrome of pain, dysautonomia and acromesomelia in a kindred with a novel NaV1.7 mutation

(2012) Janneke G. J. Hoeijmakers et al.   BRAIN

Autonomic dysfunction in SCN9A-associated primary erythromelalgia

(2012) Min-Kyeong Kim et al.   CLINICAL AUTONOMIC RESEARCH

Genetic aspects of sodium channelopathy in small fiber neuropathy

(2012) JGJ Hoeijmakers et al.   CLINICAL GENETICS

Repeatability of In Vivo Corneal Confocal Microscopy to Quantify Corneal Nerve Morphology

(2012) Ioannis N. Petropoulos et al.   CORNEA

Small fibre neuropathy

(2012) Giuseppe Lauria et al.   CURRENT OPINION IN NEUROLOGY

Corneal Confocal Microscopy Detects Early Nerve Regeneration in Diabetic Neuropathy After Simultaneous Pancreas and Kidney Transplantation

(2012) Mitra Tavakoli et al.   DIABETES

fMRI evidence of degeneration-induced neuropathic pain in diabetes: Enhanced limbic and striatal activations

(2012) Ming-Tsung Tseng et al.   HUMAN BRAIN MAPPING

Axon reflex flare and quantitative sudomotor axon reflex contribute in the diagnosis of small fiber neuropathy

(2012) Barbara Namer et al.   MUSCLE & NERVE

Corneal confocal microscopy detects small-fiber neuropathy in Charcot-Marie-Tooth disease type 1A patients

(2012) Mitra Tavakoli et al.   MUSCLE & NERVE

Cramps and small-fiber neuropathy

(2012) Glenn Lopate et al.   MUSCLE & NERVE

Small-fibre neuropathies—advances in diagnosis, pathophysiology and management

(2012) Janneke G. Hoeijmakers et al.   Nature Reviews Neurology

The NaV1.7 sodium channel: from molecule to man

(2012) Sulayman D. Dib-Hajj et al.   NATURE REVIEWS NEUROSCIENCE

Dose-response relationship after single oral dose administrations of morphine and oxycodone using laser-evoked potentials on UVB- and capsaicin-irritated skin in healthy male subjects

(2012) Eef Hoeben et al.   PAIN

Gain-of-function Nav1.8 mutations in painful neuropathy

(2012) C. G. Faber et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Gain of function NaV1.7 mutations in idiopathic small fiber neuropathy

(2011) Catharina G. Faber et al.   ANNALS OF NEUROLOGY

Microneurographic evaluation of sympathetic activity in small fiber neuropathy

(2011) Rocco Liguori et al.   CLINICAL NEUROPHYSIOLOGY

Pain perception in humans: use of intraepidermal electrical stimulation: Figure 1

(2011) Koji Inui et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Kinetic modeling of Nav1.7 provides insight into erythromelalgia-associated F1449V mutation

(2011) Meron Gurkiewicz et al.   JOURNAL OF NEUROPHYSIOLOGY

Intra- and Interfamily Phenotypic Diversity in Pain Syndromes Associated with a Gain-of-Function Variant of NaV1.7

(2011) Mark Estación et al.   Molecular Pain

Characterization of non-length-dependent small-fiber sensory neuropathy

(2011) Sara Khan et al.   MUSCLE & NERVE

Morphometry of dermal nerve fibers in human skin

(2011) G. Lauria et al.   NEUROLOGY

Unmyelinated and myelinated skin nerve damage in Guillain–Barré syndrome: Correlation with pain and recovery

(2011) Liselotte Ruts et al.   PAIN

Two NovelSCN9AGene Heterozygous Mutations May Cause Partial Deletion of Pain Perception

(2011) Ruimei Yuan et al.   PAIN MEDICINE

Severe case and literature review of primary erythromelalgia: Novel SCN9A gene mutation

(2011) Nedaa Skeik et al.   VASCULAR MEDICINE

Alternative splicing may contribute to time-dependent manifestation of inherited erythromelalgia

(2010) Jin-Sung Choi et al.   BRAIN

Alternative splicing of NaV1.7 exon 5 increases the impact of the painful PEPD mutant channel I1461T

(2010) Brian W. Jarecki et al.   Channels

The time course of CO2 laser-evoked responses and of skin nerve fibre markers after topical capsaicin in human volunteers

(2010) Michael Ragé et al.   CLINICAL NEUROPHYSIOLOGY

A Nonsense Mutation in the SCN9A Gene in Congenital Insensitivity to Pain

(2010) Mazen Kurban et al.   DERMATOLOGY

Diabetic Neuropathies: Update on Definitions, Diagnostic Criteria, Estimation of Severity, and Treatments

(2010) S. Tesfaye et al.   DIABETES CARE

European Federation of Neurological Societies/Peripheral Nerve Society Guideline on the use of skin biopsy in the diagnosis of small fiber neuropathy. Report of a joint task force of the European Fe-deration of Neurological Societies and the Peripheral Ne

(2010) G. Lauria et al.   EUROPEAN JOURNAL OF NEUROLOGY

A new Nav1.7 sodium channel mutation I234T in a child with severe pain

(2010) Hye-Sook Ahn et al.   EUROPEAN JOURNAL OF PAIN

Two novel mutations of SCN9A (Nav1.7) are associated with partial congenital insensitivity to pain

(2010) Roland Staudl et al.   EUROPEAN JOURNAL OF PAIN

Congenital insensitivity to pain: novel SCN9A missense and in-frame deletion mutations

(2010) James J. Cox et al.   HUMAN MUTATION

Pain and autonomic dysfunction in patients with sarcoidosis and small fibre neuropathy

(2010) M. Bakkers et al.   JOURNAL OF NEUROLOGY

Non-length-dependent small fibre neuropathy. Confocal microscopy study of the corneal innervation

(2010) F. Gemignani et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Nav1.7 mutations associated with paroxysmal extreme pain disorder, but not erythromelalgia, enhance Navβ4 peptide-mediated resurgent sodium currents

(2010) Jonathan W. Theile et al.   JOURNAL OF PHYSIOLOGY-LONDON

Chronic non-paroxysmal neuropathic pain — Novel phenotype of mutation in the sodium channel SCN9A gene

(2010) Ron Dabby et al.   JOURNAL OF THE NEUROLOGICAL SCIENCES

Non-length dependent small fiber neuropathy. A prospective case series

(2010) Franco Gemignani et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Intraepidermal nerve fiber density at the distal leg: a worldwide normative reference study

(2010) Giuseppe Lauria et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Mutations at opposite Ends of the DIII/S4-S5 Linker of Sodium Channel NaV1.7 Produce Distinct Pain Disorders

(2010) Xiaoyang Cheng et al.   Molecular Pain

Paroxysmal extreme pain disorder: a molecular lesion of peripheral neurons

(2010) Jin-Sung Choi et al.   Nature Reviews Neurology

Quantification of pilomotor nerves: A new tool to evaluate autonomic involvement in diabetes

(2010) M. Nolano et al.   NEUROLOGY

Microneurography: An opportunity for translational drug development in neuropathic pain

(2010) Jordi Serra   NEUROSCIENCE LETTERS

Quantitative sensory testing in the German Research Network on Neuropathic Pain (DFNS): Somatosensory abnormalities in 1236 patients with different neuropathic pain syndromes

(2010) C. Maier et al.   PAIN

On the relationship between nociceptive evoked potentials and intraepidermal nerve fiber density in painful sensory polyneuropathies

(2010) Jordi Casanova-Molla et al.   PAIN

Erythromelalgia mutation L823R shifts activation and inactivation of threshold sodium channel Nav1.7 to hyperpolarized potentials

(2009) Angelika Lampert et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Early- and late-onset inherited erythromelalgia: genotype–phenotype correlation

(2009) Chongyang Han et al.   BRAIN

Stimulated skin wrinkling for predicting intraepidermal nerve fibre density

(2009) Einar P. Wilder-Smith et al.   CLINICAL NEUROPHYSIOLOGY

Corneal Sensitivity and Slit Scanning In Vivo Confocal Microscopy of the Subbasal Nerve Plexus of the Normal Central and Peripheral Human Cornea

(2009) Dipika V Patel et al.   CORNEA

Corneal confocal microscopy: A novel means to detect nerve fibre damage in idiopathic small fibre neuropathy

(2009) Mitra Tavakoli et al.   EXPERIMENTAL NEUROLOGY

Altered resting state attentional networks in diabetic neuropathic pain

(2009) F. Cauda et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

Corneal confocal microscopy: A novel noninvasive means to diagnose neuropathy in patients with fabry disease

(2009) Mitra Tavakoli et al.   MUSCLE & NERVE

Voltage-clamp and current-clamp recordings from mammalian DRG neurons

(2009) Theodore R Cummins et al.   Nature Protocols

Laser-evoked potential P2 single-trial amplitudes covary with the fMRI BOLD response in the medial pain system and interconnected subcortical structures

(2009) A. Mobascher et al.   NEUROIMAGE

Quantification of sweat gland innervation: A clinical-pathologic correlation

(2009) C. H. Gibbons et al.   NEUROLOGY

Two novel SCN9A mutations causing insensitivity to pain

(2009) K. B. Nilsen et al.   PAIN

Altered Resting State in Diabetic Neuropathic Pain

(2009) Franco Cauda et al.   PLoS One

The diagnostic criteria for small fibre neuropathy: from symptoms to neuropathology

(2008) G. Devigili et al.   BRAIN

Sweat testing to evaluate autonomic function

(2008) Ben M. W. Illigens et al.   CLINICAL AUTONOMIC RESEARCH

Patterns of contact heat evoked potentials (CHEP) in neuropathy with skin denervation: Correlation of CHEP amplitude with intraepidermal nerve fiber density

(2008) Chi-Chao Chao et al.   CLINICAL NEUROPHYSIOLOGY

Recommendations for the clinical use of somatosensory-evoked potentials

(2008) G. Cruccu et al.   CLINICAL NEUROPHYSIOLOGY

Skin biopsy for the diagnosis of peripheral neuropathy

(2008) G Lauria et al.   HISTOPATHOLOGY

A Pore-blocking Hydrophobic Motif at the Cytoplasmic Aperture of the Closed-state Nav1.7 Channel Is Disrupted by the Erythromelalgia-associated F1449V Mutation

(2008) Angelika Lampert et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Early diabetic neuropathy: thermal thresholds and intraepidermal nerve fibre density in patients with normal nerve conduction studies

(2008) S. Løseth et al.   JOURNAL OF NEUROLOGY

Skin wrinkling for diagnosing small fibre neuropathy: comparison with epidermal nerve density and sympathetic skin response

(2008) H L Teoh et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY

NaV1.7 Gain-of-Function Mutations as a Continuum: A1632E Displays Physiological Changes Associated with Erythromelalgia and Paroxysmal Extreme Pain Disorder Mutations and Produces Symptoms of Both Disorders

(2008) M. Estacion et al.   JOURNAL OF NEUROSCIENCE

The Utah Early Neuropathy Scale: a sensitive clinical scale for early sensory predominant neuropathy

(2008) J. Robinson Singleton et al.   JOURNAL OF THE PERIPHERAL NERVOUS SYSTEM

Paroxysmal Extreme Pain Disorder M1627K Mutation in Human Nav1.7 Renders DRG Neurons Hyperexcitable

(2008) Sulayman D Dib-Hajj et al.   Molecular Pain

Mutation I136V Alters Electrophysiological Properties of the NaV1.7 Channel in a Family with Onset of Erythromelalgia in the Second Decade

(2008) Xiaoyang Cheng et al.   Molecular Pain

Age-related differences in pain sensitivity and regional brain activity evoked by noxious pressure

(2008) Leonie J. Cole et al.   NEUROBIOLOGY OF AGING

The role of learning in nocebo and placebo effects

(2008) L. Colloca et al.   PAIN

Non-length dependent small fibre neuropathy/ganglionopathy

(2007) K C Gorson et al.   JOURNAL OF NEUROLOGY NEUROSURGERY AND PSYCHIATRY