Age-related deregulation of TDP-43 after stroke enhances NF-κB-mediated inflammation and neuronal damage

Brain Response to Injuries: When Microglia Go Sexist

(2018) Reza Rahimian et al.   NEUROSCIENCE

Estrogen receptors alpha mediates postischemic inflammation in chronically estrogen-deprived mice

(2016) Pierre Cordeau et al.   NEUROBIOLOGY OF AGING

Withania somnifera Reverses Transactive Response DNA Binding Protein 43 Proteinopathy in a Mouse Model of Amyotrophic Lateral Sclerosis/Frontotemporal Lobar Degeneration

(2016) Kallol Dutta et al.   Neurotherapeutics

The Role of TDP-43 in Alzheimer’s Disease

(2015) Xiao-Long Chang et al.   MOLECULAR NEUROBIOLOGY

Neuroinflammation and comorbidities are frequently ignored factors in CNS pathology

(2015) Aurel Popa-Wagner et al.   Neural Regeneration Research

Incidence and extent of TDP-43 accumulation in aging human brain

(2015) Akiko Uchino et al.   Acta Neuropathologica Communications

Inflammation Induces TDP-43 Mislocalization and Aggregation

(2015) Ana Sofia Correia et al.   PLoS One

Astrocytic metabolic and inflammatory changes as a function of age

(2014) Tianyi Jiang et al.   AGING CELL

Neuroprotective Effects of Rhynchophylline Against Ischemic Brain Injury via Regulation of the Akt/mTOR and TLRs Signaling Pathways

(2014) Houcai Huang et al.   MOLECULES

Novel monoclonal antibodies to normal and pathologically altered human TDP-43 proteins

(2014) Linda K Kwong et al.   Acta Neuropathologica Communications

Preclinical models of stroke in aged animals with or without comorbidities: role of neuroinflammation

(2013) A.-M. Buga et al.   BIOGERONTOLOGY

Chronic neuropathologies of single and repetitive TBI: substrates of dementia?

(2013) Douglas H. Smith et al.   Nature Reviews Neurology

Toll-like receptor 2 deficiency leads to delayed exacerbation of ischemic injury

(2012) Ivan Bohacek et al.   Journal of Neuroinflammation

Galectin-3 Is Required for Resident Microglia Activation and Proliferation in Response to Ischemic Injury

(2012) M. Lalancette-Hebert et al.   JOURNAL OF NEUROSCIENCE

Acute and chronically increased immunoreactivity to phosphorylation-independent but not pathological TDP-43 after a single traumatic brain injury in humans

(2011) Victoria E. Johnson et al.   ACTA NEUROPATHOLOGICA

Pathological hallmarks of amyotrophic lateral sclerosis/frontotemporal lobar degeneration in transgenic mice produced with TDP-43 genomic fragments

(2011) Vivek Swarup et al.   BRAIN

Deregulation of TDP-43 in amyotrophic lateral sclerosis triggers nuclear factor κB–mediated pathogenic pathways

(2011) Vivek Swarup et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Accumulation of Transactive Response DNA Binding Protein 43 in Mild Cognitive Impairment and Alzheimer Disease

(2011) Cyntia Tremblay et al.   JOURNAL OF NEUROPATHOLOGY AND EXPERIMENTAL NEUROLOGY

Accumulation of Dietary Docosahexaenoic Acid in the Brain Attenuates Acute Immune Response and Development of Postischemic Neuronal Damage

(2011) Mélanie Lalancette-Hébert et al.   STROKE

The metabolic footprint of aging in mice

(2011) Riekelt H. Houtkooper et al.   Scientific Reports

Biochemical and histopathological alterations in TAR DNA-binding protein-43 after acute ischemic stroke in rats

(2010) Masato Kanazawa et al.   JOURNAL OF NEUROCHEMISTRY

TDP-43 transgenic mice develop spastic paralysis and neuronal inclusions characteristic of ALS and frontotemporal lobar degeneration

(2010) Hans Wils et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Nomenclature and nosology for neuropathologic subtypes of frontotemporal lobar degeneration: an update

(2009) Ian R. A. Mackenzie et al.   ACTA NEUROPATHOLOGICA

Multimodal microglia imaging of fiber tracts in acute subcortical stroke

(2009) Basia A. Radlinska et al.   ANNALS OF NEUROLOGY

Live imaging of Toll-like receptor 2 response in cerebral ischaemia reveals a role of olfactory bulb microglia as modulators of inflammation

(2009) M. Lalancette-Hébert et al.   BRAIN

TDP-43 Redistribution is an Early Event in Sporadic Amyotrophic Lateral Sclerosis

(2009) Maria Teresa Giordana et al.   BRAIN PATHOLOGY

Aberrant cleavage of TDP-43 enhances aggregation and cellular toxicity

(2009) Y.-J. Zhang et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Epidemiological Studies of the Effect of Stroke on Incident Dementia

(2009) George M. Savva et al.   STROKE

Phosphorylated and ubiquitinated TDP-43 pathological inclusions in ALS and FTLD-U are recapitulated in SH-SY5Y cells

(2008) Takashi Nonaka et al.   FEBS LETTERS

Disturbance of Nuclear and Cytoplasmic TAR DNA-binding Protein (TDP-43) Induces Disease-like Redistribution, Sequestration, and Aggregate Formation

(2008) Matthew J. Winton et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

TDP-43, the signature protein of FTLD-U, is a neuronal activity-responsive factor

(2008) I.-Fan Wang et al.   JOURNAL OF NEUROCHEMISTRY

TDP-43 regulates retinoblastoma protein phosphorylation through the repression of cyclin-dependent kinase 6 expression

(2008) Y. M. Ayala et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Live Imaging of Neuroinflammation Reveals Sex and Estrogen Effects on Astrocyte Response to Ischemic Injury

(2008) Pierre Cordeau et al.   STROKE