Neuroprotective Effects of Rhynchophylline Against Ischemic Brain Injury via Regulation of the Akt/mTOR and TLRs Signaling Pathways

Candesartan and glycyrrhizin ameliorate ischemic brain damage through downregulation of the TLR signaling cascade

(2014) Waleed Barakat et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

The TLR9 Ligand, CpG‐ODN, Induces Protection against Cerebral Ischemia/Reperfusion Injury via Activation of PI3K/Akt Signaling

(2014) Chen Lu et al.   Journal of the American Heart Association

Neuroprotective effect of bicyclol in rat ischemic stroke: Down-regulates TLR4, TLR9, TRAF6, NF-κB, MMP-9 and up-regulates claudin-5 expression

(2013) Jian Zhang et al.   BRAIN RESEARCH

Boosting Regulatory T Cells Limits Neuroinflammation in Permanent Cortical Stroke

(2013) A. Liesz et al.   JOURNAL OF NEUROSCIENCE

Effect of treadmill exercise on 5-HT, 5-HT1A receptor and brain derived neurophic factor in rats after permanent middle cerebral artery occlusion

(2013) Xiaofang Lan et al.   NEUROLOGICAL SCIENCES

Beneficial effects of sulindac in focal cerebral ischemia: A positive role in Wnt/β-catenin pathway

(2012) Yinxue Xing et al.   BRAIN RESEARCH

The protection by Octreotide against experimental ischemic stroke: Up-regulated transcription factor Nrf2, HO-1 and down-regulated NF-κB expression

(2012) Linyu Chen et al.   BRAIN RESEARCH

Losartan, an angiotensin II type 1 receptor blocker, ameliorates cerebral ischemia-reperfusion injury via PI3K/Akt-mediated eNOS phosphorylation

(2012) Huiqing Liu et al.   BRAIN RESEARCH BULLETIN

Rhynchophylline Protects Cultured Rat Neurons against Methamphetamine Cytotoxicity

(2012) Dan Dan Xu et al.   Evidence-based Complementary and Alternative Medicine

Cytidine-Phosphate-Guanosine Oligonucleotides Induce Interleukin-8 Production through Activation of TLR9, MyD88, NF-κB, and ERK Pathways in Odontoblast Cells

(2012) Wenxi He et al.   JOURNAL OF ENDODONTICS

Post-ischemic estradiol treatment reduced glial response and triggers distinct cortical and hippocampal signaling in a rat model of cerebral ischemia

(2012) Maria Jose Pérez-Álvarez et al.   Journal of Neuroinflammation

Progesterone is neuroprotective against ischemic brain injury through its effects on the phosphoinositide 3-kinase/protein kinase B signaling pathway

(2012) T. Ishrat et al.   NEUROSCIENCE

Protection by silibinin against experimental ischemic stroke: Up-regulated pAkt, pmTOR, HIF-1α and Bcl-2, down-regulated Bax, NF-κB expression

(2012) Chaohui Wang et al.   NEUROSCIENCE LETTERS

Experimental evidence of Ginkgo biloba extract EGB as a neuroprotective agent in ischemia stroke rats

(2011) Zhanjun Zhang et al.   BRAIN RESEARCH BULLETIN

TLR2 Ligand Induces Protection against Cerebral Ischemia/Reperfusion Injury via Activation of Phosphoinositide 3-Kinase/Akt Signaling

(2011) C. Lu et al.   JOURNAL OF IMMUNOLOGY

Acute anti-inflammatory approaches to ischemic stroke

(2010) Gregory J. Del Zoppo   Annals of the New York Academy of Sciences

Autophagy in ALDH2-elicited cardioprotection against ischemic heart disease: Slayer or savior?

(2010) Yingmei Zhang et al.   Autophagy

Tanshinone II A down-regulates HMGB1, RAGE, TLR4, NF-κB expression, ameliorates BBB permeability and endothelial cell function, and protects rat brains against focal ischemia

(2010) Lina Wang et al.   BRAIN RESEARCH

The neuroprotective effects of Tanshinone IIA are associated with induced nuclear translocation of TORC1 and upregulated expression of TORC1, pCREB and BDNF in the acute stage of ischemic stroke

(2010) Lingling Liu et al.   BRAIN RESEARCH BULLETIN

Antihypertensive and neuroprotective activities of rhynchophylline: The role of rhynchophylline in neurotransmission and ion channel activity

(2010) Jiyin Zhou et al.   JOURNAL OF ETHNOPHARMACOLOGY

Thrombolysis With Plasmin: Implications for Stroke Treatment

(2010) V. J. Marder et al.   STROKE

Curcumin upregulates transcription factor Nrf2, HO-1 expression and protects rat brains against focal ischemia

(2009) Chenhui Yang et al.   BRAIN RESEARCH

Differential roles of TLR2 and TLR4 in acute focal cerebral ischemia/reperfusion injury in mice

(2009) Fang Hua et al.   BRAIN RESEARCH

Toll-like receptor 9 inhibition confers protection from liver ischemia-reperfusion injury

(2009) Zubin M. Bamboat et al.   HEPATOLOGY

Anti-inflammatory effects of rhynchophylline and isorhynchophylline in mouse N9 microglial cells and the molecular mechanism

(2009) Dan Yuan et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

New Insights in the Biology of BDNF Synthesis and Release: Implications in CNS Function

(2009) M. E. Greenberg et al.   JOURNAL OF NEUROSCIENCE

Neurotrophic Support and Oxidative Stress: Converging Effects in the Normal and Diseased Nervous System

(2009) John Gardiner et al.   NEUROSCIENTIST

The Akt signaling pathway contributes to postconditioning’s protection against stroke; the protection is associated with the MAPK and PKC pathways

(2008) Xuwen Gao et al.   JOURNAL OF NEUROCHEMISTRY

Preconditioning with a TLR2 specific ligand increases resistance to cerebral ischemia/reperfusion injury

(2008) Fang Hua et al.   JOURNAL OF NEUROIMMUNOLOGY