Molecular Imaging of Neuroinflammation in HIV

Microglial activation is inversely associated with cognition in individuals living with HIV on effective antiretroviral therapy

(2018) Leah H. Rubin et al.   AIDS

Longitudinal Trajectories of Brain Volume and Cortical Thickness in Treated and Untreated Primary Human Immunodeficiency Virus Infection

(2018) Ryan Sanford et al.   CLINICAL INFECTIOUS DISEASES

PET Imaging of Microglial Activation—Beyond Targeting TSPO

(2018) Bieneke Janssen et al.   MOLECULES

Molecular imaging of neuroinflammation in Alzheimer's disease and mild cognitive impairment

(2018) Dunja Knezevic et al.   PROGRESS IN NEURO-PSYCHOPHARMACOLOGY & BIOLOGICAL PSYCHIATRY

Pro-inflammatory activation of primary microglia and macrophages increases 18 kDa translocator protein expression in rodents but not humans

(2017) David R Owen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Purinergic receptors P2Y12R and P2X7R: potential targets for PET imaging of microglia phenotypes in multiple sclerosis

(2017) Wissam Beaino et al.   Journal of Neuroinflammation

Reconceptualization of translocator protein as a biomarker of neuroinflammation in psychiatry

(2017) T Notter et al.   MOLECULAR PSYCHIATRY

11 C-PBR28 binding to translocator protein increases with progression of Alzheimer's disease

(2016) William C. Kreisl et al.   NEUROBIOLOGY OF AGING

Neuroinflammation in treated HIV-positive individuals

(2016) Jaime H. Vera et al.   NEUROLOGY

Cerebellum Can Serve As a Pseudo-Reference Region in Alzheimer Disease to Detect Neuroinflammation Measured with PET Radioligand Binding to Translocator Protein

(2015) C. H. Lyoo et al.   JOURNAL OF NUCLEAR MEDICINE

Peripheral Benzodiazepine Receptor/Translocator Protein Global Knock-out Mice Are Viable with No Effects on Steroid Hormone Biosynthesis

(2014) Lan N. Tu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Determination of [11C]PBR28 Binding Potential in vivo: A First Human TSPO Blocking Study

(2014) David R Owen et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

Translocator Protein 18 kDa Negatively Regulates Inflammation in Microglia

(2014) Keun-Ryung Bae et al.   Journal of Neuroimmune Pharmacology

Regional brain distribution of translocator protein using [11C]DPA-713 PET in individuals infected with HIV

(2014) Jennifer M. Coughlin et al.   JOURNAL OF NEUROVIROLOGY

In Vivo Detection of Diffuse Inflammation in Secondary Progressive Multiple Sclerosis Using PET Imaging and the Radioligand 11C-PK11195

(2014) E. Rissanen et al.   JOURNAL OF NUCLEAR MEDICINE

Role of Neuroimaging in HIV-Associated Neurocognitive Disorders

(2014) Mary Masters et al.   SEMINARS IN NEUROLOGY

Increased microglia activation in neurologically asymptomatic HIV-infected patients receiving effective ART

(2013) Lucy J. Garvey et al.   AIDS

In vivo radioligand binding to translocator protein correlates with severity of Alzheimer’s disease

(2013) William C. Kreisl et al.   BRAIN

HIV-associated neurocognitive disorder

(2013) David B Clifford et al.   LANCET INFECTIOUS DISEASES

HIV-1-Related Central Nervous System Disease: Current Issues in Pathogenesis, Diagnosis, and Treatment

(2013) S. Spudich et al.   Cold Spring Harbor Perspectives in Medicine

The Role of 18 kDa Mitochondrial Translocator Protein (TSPO) in Programmed Cell Death, and Effects of Steroids on TSPO Expression

(2012) L. Veenman et al.   CURRENT MOLECULAR MEDICINE

A Genetic Polymorphism for Translocator Protein 18 Kda Affects both in Vitro and in Vivo Radioligand Binding in Human Brain to this Putative Biomarker of Neuroinflammation

(2012) William C Kreisl et al.   JOURNAL OF CEREBRAL BLOOD FLOW AND METABOLISM

HIV-associated neurocognitive disorders: ‘mind the gap’

(2010) Justin C McArthur et al.   ANNALS OF NEUROLOGY

HIV-associated neurocognitive disorders persist in the era of potent antiretroviral therapy: CHARTER Study

(2010) R. K. Heaton et al.   NEUROLOGY

Pathogenesis of HIV in the Central Nervous System

(2010) Victor Valcour et al.   Current HIV/AIDS Reports

Comparative Evaluation of the Translocator Protein Radioligands 11C-DPA-713, 18F-DPA-714, and 11C-PK11195 in a Rat Model of Acute Neuroinflammation

(2009) F. Chauveau et al.   JOURNAL OF NUCLEAR MEDICINE

A comparative autoradiography study in post mortem whole hemisphere human brain slices taken from Alzheimer patients and age-matched controls using two radiolabelled DAA1106 analogues with high affinity to the peripheral benzodiazepine receptor (PBR) system

(2008) Balázs Gulyás et al.   NEUROCHEMISTRY INTERNATIONAL