Crosstalk in transition: the translocation of Akt

An improved Akt reporter reveals intra- and inter-cellular heterogeneity and oscillations in signal transduction

(2017) Dougall M. Norris et al.   JOURNAL OF CELL SCIENCE

The Akt switch model: Is location sufficient?

(2016) Catheryn W. Gray et al.   JOURNAL OF THEORETICAL BIOLOGY

Reversible cryo-arrest for imaging molecules in living cells at high spatial resolution

(2016) Martin E Masip et al.   NATURE METHODS

Ubl4A is required for insulin-induced Akt plasma membrane translocation through promotion of Arp2/3-dependent actin branching

(2015) Yu Zhao et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Non-canonical Activation of Akt in Serum-Stimulated Fibroblasts, Revealed by Comparative Modeling of Pathway Dynamics

(2015) Tri Hieu Nim et al.   PLoS Computational Biology

Regulatory interactions maintaining self-renewal of human embryonic stem cells as revealed through a systems analysis of PI3K/AKT pathway

(2014) Shibin Mathew et al.   BIOINFORMATICS

A novel method for simulating insulin mediated GLUT4 translocation

(2014) Andrew J. Jezewski et al.   BIOTECHNOLOGY AND BIOENGINEERING

Quantitative analysis of robustness of dynamic response and signal transfer in insulin mediated PI3K/AKT pathway

(2014) Shibin Mathew et al.   COMPUTERS & CHEMICAL ENGINEERING

NSC126188 induces apoptosis of prostate cancer PC-3 cells through inhibition of Akt membrane translocation, FoxO3a activation, and RhoB transcription

(2013) Kyoung-Jae Won et al.   APOPTOSIS

PI3 kinase directly phosphorylates Akt1/2 at Ser473/474 in the insulin signal transduction pathway

(2013) A Tsuchiya et al.   JOURNAL OF ENDOCRINOLOGY

Growth regulation and the insulin signaling pathway

(2013) Peter W. Bates et al.   Networks and Heterogeneous Media

Computational Model of Gab1/2-Dependent VEGFR2 Pathway to Akt Activation

(2013) Wan Hua Tan et al.   PLoS One

A new mathematical approach for qualitative modeling of the insulin-TOR-MAPK network

(2013) H. Frederik Nijhout et al.   Frontiers in Physiology

A Ceramide-Centric View of Insulin Resistance

(2012) Jose A. Chavez et al.   Cell Metabolism

Temporal Coding of Insulin Action through Multiplexing of the AKT Pathway

(2012) Hiroyuki Kubota et al.   MOLECULAR CELL

Heterogeneous kinetics of AKT signaling in individual cells are accounted for by variable protein concentration

(2012) René Meyer et al.   Frontiers in Physiology

The Akt kinases: Isoform specificity in metabolism and cancer

(2011) Eva Gonzalez et al.   CELL CYCLE

Akt signalling in health and disease

(2011) Ingeborg Hers et al.   CELLULAR SIGNALLING

Modelling and analysis of an ensemble of eukaryotic translation initiation models

(2011) S. Nayak et al.   IET Systems Biology

Amplification and Demultiplexing in Insulin-regulated Akt Protein Kinase Pathway in Adipocytes

(2011) Shi-Xiong Tan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Mapping Insulin/GLUT4 Circuitry

(2011) Alexander F. Rowland et al.   TRAFFIC

Cluster Analysis of Insulin Action in Adipocytes Reveals a Key Role for Akt at the Plasma Membrane

(2009) Yvonne Ng et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Insulin-modulated Akt subcellular localization determines Akt isoform-specific signaling

(2009) E. Gonzalez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Rapid Activation of Akt2 Is Sufficient to Stimulate GLUT4 Translocation in 3T3-L1 Adipocytes

(2008) Yvonne Ng et al.   Cell Metabolism

Pharmacokinetic/Pharmacodynamic Modelling in??Diabetes Mellitus

(2008) Cornelia B Landersdorfer et al.   CLINICAL PHARMACOKINETICS