Computational Model of Gab1/2-Dependent VEGFR2 Pathway to Akt Activation

Cross-talk between mitogenic Ras/MAPK and survival PI3K/Akt pathways: a fine balance

(2012) Edita Aksamitiene et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

The VEGFR2 receptor tyrosine kinase undergoes constitutive endosome-to-plasma membrane recycling

(2011) Helen M. Jopling et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Signal transduction by vascular endothelial growth factor receptors

(2011) Sina Koch et al.   BIOCHEMICAL JOURNAL

Chronic CRP-Exposure Inhibits VEGF-Induced Endothelial Cell Migration

(2011) Christopher Schneeweis et al.   Journal of Atherosclerosis and Thrombosis

Vascular endothelial growth factors and receptors: Anti-angiogenic therapy in the treatment of cancer

(2011) Sònia Tugues et al.   MOLECULAR ASPECTS OF MEDICINE

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

VEGF Receptor 2 Endocytic Trafficking Regulates Arterial Morphogenesis

(2010) Anthony A. Lanahan et al.   DEVELOPMENTAL CELL

Quantification and cell-to-cell variation of vascular endothelial growth factor receptors

(2010) P.I. Imoukhuede et al.   EXPERIMENTAL CELL RESEARCH

Systematic Quantification of Negative Feedback Mechanisms in the Extracellular Signal-regulated Kinase (ERK) Signaling Network

(2010) Murat Cirit et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Ephrin-B2 regulates VEGFR2 function in developmental and tumour angiogenesis

(2010) Suphansa Sawamiphak et al.   NATURE

Pathway-Based Identification of Biomarkers for Targeted Therapeutics: Personalized Oncology with PI3K Pathway Inhibitors

(2010) J. N. Andersen et al.   Science Translational Medicine

In control at the ER: PTP1B and the down-regulation of RTKs by dephosphorylation and endocytosis

(2010) Matthew Stuible et al.   TRENDS IN CELL BIOLOGY

Gab2-Mediated Signaling Promotes Melanoma Metastasis

(2009) Basil Horst et al.   AMERICAN JOURNAL OF PATHOLOGY

VEGF receptor trafficking in angiogenesis: Figure 1

(2009) Alice Scott et al.   BIOCHEMICAL SOCIETY TRANSACTIONS

Function, regulation and pathological roles of the Gab/DOS docking proteins

(2009) Franziska U Wöhrle et al.   Cell Communication and Signaling

VEGF-dependent tumor angiogenesis requires inverse and reciprocal regulation of VEGFR1 and VEGFR2

(2009) Z Zhang et al.   CELL DEATH AND DIFFERENTIATION

Non-redundant roles of the Gab1 and Gab2 scaffolding adapters in VEGF-mediated signalling, migration, and survival of endothelial cells

(2009) Christine Caron et al.   CELLULAR SIGNALLING

Quantification of endothelial cell-targeted anti-Bcl-2 therapy and its suppression of tumor growth and vascularization

(2009) H. V. Jain et al.   MOLECULAR CANCER THERAPEUTICS

Systems-level interactions between insulin–EGF networks amplify mitogenic signaling

(2009) Nikolay Borisov et al.   Molecular Systems Biology

Therapeutically Targeting ErbB3: A Key Node in Ligand-Induced Activation of the ErbB Receptor-PI3K Axis

(2009) B. Schoeberl et al.   Science Signaling

Ligand-Stimulated VEGFR2 Signaling is Regulated by Co-Ordinated Trafficking and Proteolysis

(2009) Alexander F. Bruns et al.   TRAFFIC

The Presence of VEGF Receptors on the Luminal Surface of Endothelial Cells Affects VEGF Distribution and VEGF Signaling

(2009) Marianne O. Stefanini et al.   PLoS Computational Biology

Phosphorylation-dependent binding of 14-3-3 terminates signalling by the Gab2 docking protein

(2008) Tilman Brummer et al.   EMBO JOURNAL

A methodology for performing global uncertainty and sensitivity analysis in systems biology

(2008) Simeone Marino et al.   JOURNAL OF THEORETICAL BIOLOGY

New Role for the Protein Tyrosine Phosphatase DEP-1 in Akt Activation and Endothelial Cell Survival

(2008) C. Chabot et al.   MOLECULAR AND CELLULAR BIOLOGY

Modular cell biology: retroactivity and insulation

(2008) Domitilla Del Vecchio et al.   Molecular Systems Biology

CellDesigner 3.5: A Versatile Modeling Tool for Biochemical Networks

(2008) A. Funahashi et al.   PROCEEDINGS OF THE IEEE