Differential and Overlapping Immune Programs Regulated by IRF3 and IRF5 in Plasmacytoid Dendritic Cells

Specific detection of interferon regulatory factor 5 (IRF5): A case of antibody inequality

(2016) Dan Li et al.   Scientific Reports

Monocyte Heterogeneity: Consequences for Monocyte-Derived Immune Cells

(2016) Sara Sprangers et al.   Journal of Immunology Research

IRF5 and IRF8 modulate the CAL-1 human plasmacytoid dendritic cell line response following TLR9 ligation

(2015) Folkert Steinhagen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IFN-  production by plasmacytoid dendritic cell associations with polymorphisms in gene loci related to autoimmune and inflammatory diseases

(2015) O. Berggren et al.   HUMAN MOLECULAR GENETICS

RIG-I in RNA virus recognition

(2015) Alison M. Kell et al.   VIROLOGY

Cytokines and chemokines: At the crossroads of cell signalling and inflammatory disease

(2014) Mark D. Turner et al.   BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH

Interferon regulatory factor 3 as key element of the interferon signature in plasmacytoid dendritic cells from systemic lupus erythematosus patients: novel genetic associations in the Mexican mestizo population

(2014) K. Santana-de Anda et al.   CLINICAL AND EXPERIMENTAL IMMUNOLOGY

TLR ligands upregulate RIG-I expression in human plasmacytoid dendritic cells in a type I IFN-independent manner

(2014) Attila Szabo et al.   IMMUNOLOGY AND CELL BIOLOGY

Interferon Regulatory Factor 5-Dependent Immune Responses in the Draining Lymph Node Protect against West Nile Virus Infection

(2014) L. B. Thackray et al.   JOURNAL OF VIROLOGY

IKKβ is an IRF5 kinase that instigates inflammation

(2014) Junyao Ren et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Protein kinase IKKβ-catalyzed phosphorylation of IRF5 at Ser462 induces its dimerization and nuclear translocation in myeloid cells

(2014) Marta Lopez-Pelaez et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

MicroRNA-146a regulates survival and maturation of human plasmacytoid dendritic cells

(2013) J. J. Karrich et al.   BLOOD

IRF-5 and NF-κB p50 co-regulate IFN-β and IL-6 expression in TLR9-stimulated human plasmacytoid dendritic cells

(2013) Folkert Steinhagen et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

IRF5, IRF8, and IRF7 in human pDCs - the good, the bad, and the insignificant?

(2013) Karin Pelka et al.   EUROPEAN JOURNAL OF IMMUNOLOGY

Interferon regulatory factor 5 and autoimmune lupus

(2013) Wang-Dong Xu et al.   EXPERT REVIEWS IN MOLECULAR MEDICINE

Human dendritic cell subsets

(2013) Matthew Collin et al.   IMMUNOLOGY

Phenotype and function of B cells and dendritic cells from interferon regulatory factor 5-deficient mice with and without a mutation in DOCK2

(2013) K. Yasuda et al.   INTERNATIONAL IMMUNOLOGY

The Essential, Nonredundant Roles of RIG-I and MDA5 in Detecting and Controlling West Nile Virus Infection

(2013) J. S. Errett et al.   JOURNAL OF VIROLOGY

Hepatitis C Virus Pathogen Associated Molecular Pattern (PAMP) Triggers Production of Lambda-Interferons by Human Plasmacytoid Dendritic Cells

(2013) Amy E. L. Stone et al.   PLoS Pathogens

IRF-3, IRF-5, and IRF-7 Coordinately Regulate the Type I IFN Response in Myeloid Dendritic Cells Downstream of MAVS Signaling

(2013) Helen M. Lazear et al.   PLoS Pathogens

The transcription factor Spi-B regulates human plasmacytoid dendritic cell survival through direct induction of the antiapoptotic gene BCL2-A1

(2012) J. J. Karrich et al.   BLOOD

Unique contribution of IRF-5-Ikaros axis to the B-cell IgG2a response

(2012) C-M Fang et al.   GENES AND IMMUNITY

Plasmacytoid dendritic cells have a cytokine-producing capacity to enhance ICOS ligand-mediated IL-10 production during T-cell priming

(2012) Makoto Ogata et al.   INTERNATIONAL IMMUNOLOGY

IRF5 Risk Polymorphisms Contribute to Interindividual Variance in Pattern Recognition Receptor-Mediated Cytokine Secretion in Human Monocyte-Derived Cells

(2012) M. Hedl et al.   JOURNAL OF IMMUNOLOGY

Activation of type I interferon-dependent genes characterizes the “core response” induced by CpG DNA

(2012) Folkert Steinhagen et al.   JOURNAL OF LEUKOCYTE BIOLOGY

Two new monoclonal antibodies for biochemical and flow cytometric analyses of human interferon regulatory factor-3 activation, turnover, and depletion

(2012) Arjun Rustagi et al.   METHODS

Activation of Interferon Regulatory Factor 5 by Site Specific Phosphorylation

(2012) Hui-Chen Chang Foreman et al.   PLoS One

Spontaneous mutation of the Dock2 gene in Irf5-/- mice complicates interpretation of type I interferon production and antibody responses

(2012) W. E. Purtha et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Uridine Composition of the Poly-U/UC Tract of HCV RNA Defines Non-Self Recognition by RIG-I

(2012) Gretja Schnell et al.   PLoS Pathogens

IRF5 haplotypes demonstrate diverse serological associations which predict serum interferon alpha activity and explain the majority of the genetic association with systemic lupus erythematosus

(2011) Timothy B Niewold et al.   ANNALS OF THE RHEUMATIC DISEASES

Interferon regulatory factor 5 activation in monocytes of systemic lupus erythematosus patients is triggered by circulating autoantigens independent of type I interferons

(2011) Rivka C. Stone et al.   ARTHRITIS AND RHEUMATISM

IRF7: activation, regulation, modification and function

(2011) S Ning et al.   GENES AND IMMUNITY

Immune Signaling by RIG-I-like Receptors

(2011) Yueh-Ming Loo et al.   IMMUNITY

Myxoma Virus Induces Type I Interferon Production in Murine Plasmacytoid Dendritic Cells via a TLR9/MyD88-, IRF5/IRF7-, and IFNAR-Dependent Pathway

(2011) P. Dai et al.   JOURNAL OF VIROLOGY

Critical Role of IRF-5 in the Development of T helper 1 responses to Leishmania donovani infection

(2011) Andrea Paun et al.   PLoS Pathogens

IRF5 is required for late-phase TNF secretion by human dendritic cells

(2010) T. Krausgruber et al.   BLOOD

Association of IRF5 polymorphisms with activation of the interferon   pathway

(2009) O. J. Rullo et al.   ANNALS OF THE RHEUMATIC DISEASES

IKKα negatively regulates IRF-5 function in a MyD88–TRAF6 pathway

(2009) Mumtaz Yaseen Balkhi et al.   CELLULAR SIGNALLING

Nucleotide Sequences and Modifications That Determine RIG-I/RNA Binding and Signaling Activities

(2009) D. Uzri et al.   JOURNAL OF VIROLOGY

A leukemic plasmacytoid dendritic cell line, PMDC05, with the ability to secrete IFN-α by stimulation via Toll-like receptors and present antigens to naïve T cells

(2009) Miwako Narita et al.   LEUKEMIA RESEARCH

Association of the IRF5 risk haplotype with high serum interferon-α activity in systemic lupus erythematosus patients

(2008) Timothy B. Niewold et al.   ARTHRITIS AND RHEUMATISM

Interferon regulatory factor-5 is genetically associated with systemic lupus erythematosus in African Americans

(2008) J A Kelly et al.   GENES AND IMMUNITY

Functional Characterization of Murine Interferon Regulatory Factor 5 (IRF-5) and Its Role in the Innate Antiviral Response

(2008) Andrea Paun et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential recognition of double-stranded RNA by RIG-I–like receptors in antiviral immunity: Figure 1.

(2008) Takeshi Saito et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Promoter polymorphisms in the IRF3 gene confer protection against systemic lupus erythematosus

(2008) M Akahoshi et al.   LUPUS

Functional Regulation of MyD88-Activated Interferon Regulatory Factor 5 by K63-Linked Polyubiquitination

(2008) M. Y. Balkhi et al.   MOLECULAR AND CELLULAR BIOLOGY

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

(2008) Takeshi Saito et al.   NATURE

Insights into interferon regulatory factor activation from the crystal structure of dimeric IRF5

(2008) Weijun Chen et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Association between the rs2004640 functional polymorphism of interferon regulatory factor 5 and systemic lupus erythematosus: a meta-analysis

(2008) Young Ho Lee et al.   RHEUMATOLOGY INTERNATIONAL