Hepatitis C Virus Pathogen Associated Molecular Pattern (PAMP) Triggers Production of Lambda-Interferons by Human Plasmacytoid Dendritic Cells

HCV Infection Induces a Unique Hepatic Innate Immune Response Associated With Robust Production of Type III Interferons

(2012) Emmanuel Thomas et al.   GASTROENTEROLOGY

Type I interferon negatively controls plasmacytoid dendritic cell numbers in vivo

(2011) Melissa Swiecki et al.   JOURNAL OF EXPERIMENTAL MEDICINE

Chronic Hepatitis C Infection

(2011) Hugo R. Rosen   NEW ENGLAND JOURNAL OF MEDICINE

Plasmacytoid dendritic cells: key players in the initiation and regulation of immune responses

(2010) Roberto Lande et al.   Annals of the New York Academy of Sciences

RIG-I Detects Viral Genomic RNA during Negative-Strand RNA Virus Infection

(2010) Jan Rehwinkel et al.   CELL

IL28B and the Control of Hepatitis C Virus Infection

(2010) Ashwin Balagopal et al.   GASTROENTEROLOGY

Plasmacytoid Dendritic Cell Ablation Impacts Early Interferon Responses and Antiviral NK and CD8+ T Cell Accrual

(2010) Melissa Swiecki et al.   IMMUNITY

A Common Polymorphism in the Caspase Recruitment Domain of RIG-I Modifies the Innate Immune Response of Human Dendritic Cells

(2010) J. Hu et al.   JOURNAL OF IMMUNOLOGY

Extracellular 2'-5' Oligoadenylate Synthetase Stimulates RNase L-Independent Antiviral Activity: a Novel Mechanism of Virus-Induced Innate Immunity

(2010) H. Kristiansen et al.   JOURNAL OF VIROLOGY

Comparative Analysis of the Lambda-Interferons IL-28A and IL-29 regarding Their Transcriptome and Their Antiviral Properties against Hepatitis C Virus

(2010) Julia Diegelmann et al.   PLoS One

Plasmacytoid dendritic cells sense hepatitis C virus-infected cells, produce interferon, and inhibit infection

(2010) K. Takahashi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Hepatitis C Treatment: current and future perspectives

(2010) Saira Munir et al.   Virology Journal

Experimental models for hepatitis C viral infection

(2009) Andre Boonstra et al.   HEPATOLOGY

Cutting Edge: TLR-Dependent Viral Recognition Along with Type I IFN Positive Feedback Signaling Masks the Requirement of Viral Replication for IFN-  Production in Plasmacytoid Dendritic Cells

(2009) Y. Kumagai et al.   JOURNAL OF IMMUNOLOGY

Intracellular Innate Immune Cascades and Interferon Defenses That Control Hepatitis C Virus

(2009) Stacy M. Horner et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Inhibition of Type III Interferon Activity by Orthopoxvirus Immunomodulatory Proteins

(2009) Prasanthi Bandi et al.   JOURNAL OF INTERFERON AND CYTOKINE RESEARCH

Nucleotide Sequences and Modifications That Determine RIG-I/RNA Binding and Signaling Activities

(2009) D. Uzri et al.   JOURNAL OF VIROLOGY

Genetic variation in IL28B predicts hepatitis C treatment-induced viral clearance

(2009) Dongliang Ge et al.   NATURE

Genetic variation in IL28B and spontaneous clearance of hepatitis C virus

(2009) David L. Thomas et al.   NATURE

MDA5/RIG-I and virus recognition

(2008) Osamu Takeuchi et al.   CURRENT OPINION IN IMMUNOLOGY

Innate immunity induced by composition-dependent RIG-I recognition of hepatitis C virus RNA

(2008) Takeshi Saito et al.   NATURE

The role of viral nucleic acid recognition in dendritic cells for innate and adaptive antiviral immunity

(2007) Katharina Eisenächer et al.   IMMUNOBIOLOGY