Exploring the role of the HNF-1αG319S polymorphism in β cell failure and youth-onset type 2 diabetes: Lessons from MODY and Hnf-1α-deficient animal models
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Title
Exploring the role of the HNF-1αG319S polymorphism in β cell failure and youth-onset type 2 diabetes: Lessons from MODY and Hnf-1α-deficient animal models
Authors
Keywords
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Journal
Biochemistry and Cell Biology
Volume 93, Issue 5, Pages 487-494
Publisher
Canadian Science Publishing
Online
2015-05-07
DOI
10.1139/bcb-2015-0021
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Note: Only part of the references are listed.- Earlier Onset of Complications in Youth With Type 2 Diabetes
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- Clinical and Demographic Characteristics of Type 2 Diabetes in Youth at Diagnosis in Manitoba and Northwestern Ontario (2006–2011)
- (2012) Elizabeth A.C. Sellers et al. Canadian Journal of Diabetes
- High Burden of Kidney Disease in Youth-Onset Type 2 Diabetes
- (2012) A. B. Dart et al. DIABETES CARE
- β-Cell Uncoupling Protein 2 Regulates Reactive Oxygen Species Production, Which Influences Both Insulin and Glucagon Secretion
- (2011) Christine A. Robson-Doucette et al. DIABETES
- Activation of the GLP-1 Receptor Signalling Pathway: A Relevant Strategy to Repair a Deficient Beta-Cell Mass
- (2011) Bernard Portha et al. Experimental Diabetes Research
- Type 2 Diabetes, Medication-Induced Diabetes, and Monogenic Diabetes in Canadian Children: A prospective national surveillance study
- (2010) S. Amed et al. DIABETES CARE
- Maternal obesity in ewes results in reduced fetal pancreatic β-cell numbers in late gestation and decreased circulating insulin concentration at term
- (2010) L. Zhang et al. DOMESTIC ANIMAL ENDOCRINOLOGY
- Hepatocyte growth factor activator (HGFA): a serine protease that links tissue injury to activation of hepatocyte growth factor
- (2010) Keiji Miyazawa FEBS Journal
- Distinct Regulation of Hepatic Nuclear Factor 1α by NKX6.1 in Pancreatic Beta Cells
- (2010) William Donelan et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Hnf1α (MODY3) Regulates β-Cell-Enriched MafA Transcription Factor Expression
- (2010) Chad S. Hunter et al. MOLECULAR ENDOCRINOLOGY
- Maternal obesity accelerates fetal pancreatic β-cell but not α-cell development in sheep: prenatal consequences
- (2009) Stephen P. Ford et al. AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY
- Mitochondrial Dysfunction Contributes to Impaired Insulin Secretion in INS-1 Cells with Dominant-negative Mutations of HNF-1α and in HNF-1α-deficient Islets
- (2009) Rebecca L. Pongratz et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Uncoupling protein 2 regulates reactive oxygen species formation in islets and influences susceptibility to diabetogenic action of streptozotocin
- (2009) Simon C Lee et al. JOURNAL OF ENDOCRINOLOGY
- Diabetes Susceptibility in the Canadian Oji-Cree Population Is Moderated by Abnormal mRNA Processing of HNF1A G319S Transcripts
- (2008) L. W. Harries et al. DIABETES
- Transcription factor expression in the developing human fetal endocrine pancreas
- (2008) B. M. Lyttle et al. DIABETOLOGIA
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