Exploring the role of the HNF-1αG319S polymorphism in β cell failure and youth-onset type 2 diabetes: Lessons from MODY and Hnf-1α-deficient animal models

Earlier Onset of Complications in Youth With Type 2 Diabetes

(2013) A. B. Dart et al.   DIABETES CARE

Maternal Obesity during the Preconception and Early Life Periods Alters Pancreatic Development in Early and Adult Life in Male Mouse Offspring

(2013) Isabele Bringhenti et al.   PLoS One

Identification of hepatocyte growth factor activator (Hgfac) gene as a target of HNF1α in mouse β-cells

(2012) Tsuyoshi Ohki et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Clinical and Demographic Characteristics of Type 2 Diabetes in Youth at Diagnosis in Manitoba and Northwestern Ontario (2006–2011)

(2012) Elizabeth A.C. Sellers et al.   Canadian Journal of Diabetes

High Burden of Kidney Disease in Youth-Onset Type 2 Diabetes

(2012) A. B. Dart et al.   DIABETES CARE

β-Cell Uncoupling Protein 2 Regulates Reactive Oxygen Species Production, Which Influences Both Insulin and Glucagon Secretion

(2011) Christine A. Robson-Doucette et al.   DIABETES

Activation of the GLP-1 Receptor Signalling Pathway: A Relevant Strategy to Repair a Deficient Beta-Cell Mass

(2011) Bernard Portha et al.   Experimental Diabetes Research

Type 2 Diabetes, Medication-Induced Diabetes, and Monogenic Diabetes in Canadian Children: A prospective national surveillance study

(2010) S. Amed et al.   DIABETES CARE

Maternal obesity in ewes results in reduced fetal pancreatic β-cell numbers in late gestation and decreased circulating insulin concentration at term

(2010) L. Zhang et al.   DOMESTIC ANIMAL ENDOCRINOLOGY

Hepatocyte growth factor activator (HGFA): a serine protease that links tissue injury to activation of hepatocyte growth factor

(2010) Keiji Miyazawa   FEBS Journal

Distinct Regulation of Hepatic Nuclear Factor 1α by NKX6.1 in Pancreatic Beta Cells

(2010) William Donelan et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Hnf1α (MODY3) Regulates β-Cell-Enriched MafA Transcription Factor Expression

(2010) Chad S. Hunter et al.   MOLECULAR ENDOCRINOLOGY

Maternal obesity accelerates fetal pancreatic β-cell but not α-cell development in sheep: prenatal consequences

(2009) Stephen P. Ford et al.   AMERICAN JOURNAL OF PHYSIOLOGY-REGULATORY INTEGRATIVE AND COMPARATIVE PHYSIOLOGY

Mitochondrial Dysfunction Contributes to Impaired Insulin Secretion in INS-1 Cells with Dominant-negative Mutations of HNF-1α and in HNF-1α-deficient Islets

(2009) Rebecca L. Pongratz et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Uncoupling protein 2 regulates reactive oxygen species formation in islets and influences susceptibility to diabetogenic action of streptozotocin

(2009) Simon C Lee et al.   JOURNAL OF ENDOCRINOLOGY

Diabetes Susceptibility in the Canadian Oji-Cree Population Is Moderated by Abnormal mRNA Processing of HNF1A G319S Transcripts

(2008) L. W. Harries et al.   DIABETES

Transcription factor expression in the developing human fetal endocrine pancreas

(2008) B. M. Lyttle et al.   DIABETOLOGIA