Inotropic interventions do not change the resting state of myosin motors during cardiac diastole

The force and stiffness of myosin motors in the isometric twitch of a cardiac trabecula and the effect of the extracellular calcium concentration

(2018) Francesca Pinzauti et al.   JOURNAL OF PHYSIOLOGY-LONDON

Thick Filament Mechano-Sensing in Skeletal and Cardiac Muscles: A Common Mechanism Able to Adapt the Energetic Cost of the Contraction to the Task

(2018) Gabriella Piazzesi et al.   Frontiers in Physiology

A multipurpose instrument for time-resolved ultra-small-angle and coherent X-ray scattering

(2018) Theyencheri Narayanan et al.   JOURNAL OF APPLIED CRYSTALLOGRAPHY

Phosphorylation of cardiac myosin binding protein C releases myosin heads from the surface of cardiac thick filaments

(2017) Robert W. Kensler et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myosin filament activation in the heart is tuned to the mechanical task

(2017) Massimo Reconditi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Distinct contributions of the thin and thick filaments to length-dependent activation in heart muscle

(2017) Xuemeng Zhang et al.   eLife

Effects of myosin variants on interacting-heads motif explain distinct hypertrophic and dilated cardiomyopathy phenotypes

(2017) Lorenzo Alamo et al.   eLife

Size and speed of the working stroke of cardiac myosin in situ

(2016) Marco Caremani et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myosin light chain phosphorylation enhances contraction of heart muscle via structural changes in both thick and thin filaments

(2016) Thomas Kampourakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Titin strain contributes to the Frank–Starling law of the heart by structural rearrangements of both thin- and thick-filament proteins

(2016) Younss Ait-Mou et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Cardiac Myosin Binding Protein-C Phosphorylation Modulates Myofilament Length-Dependent Activation

(2016) Ranganath Mamidi et al.   Frontiers in Physiology

The myosin mesa and a possible unifying hypothesis for the molecular basis of human hypertrophic cardiomyopathy

(2015) James A. Spudich   BIOCHEMICAL SOCIETY TRANSACTIONS

Cardiac Myosin-binding Protein C and Troponin-I Phosphorylation Independently Modulate Myofilament Length-dependent Activation

(2015) Mohit Kumar et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Force generation by skeletal muscle is controlled by mechanosensing in myosin filaments

(2015) Marco Linari et al.   NATURE

Hypertrophic and Dilated Cardiomyopathy: Four Decades of Basic Research on Muscle Lead to Potential Therapeutic Approaches to These Devastating Genetic Diseases

(2014) James A. Spudich   BIOPHYSICAL JOURNAL

The contributions of filaments and cross-bridges to sarcomere compliance in skeletal muscle

(2014) Elisabetta Brunello et al.   JOURNAL OF PHYSIOLOGY-LONDON

Myosin binding protein-C activates thin filaments and inhibits thick filaments in heart muscle cells

(2014) Thomas Kampourakis et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myosin-binding protein C displaces tropomyosin to activate cardiac thin filaments and governs their speed by an independent mechanism

(2014) Ji Young Mun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Length-dependent changes in contractile dynamics are blunted due to cardiac myosin binding protein-C ablation

(2014) Ranganath Mamidi et al.   Frontiers in Physiology

Sarcomere-length dependence of myosin filament structure in skeletal muscle fibres of the frog

(2013) Massimo Reconditi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Tuning the molecular giant titin through phosphorylation: Role in health and disease

(2013) Carlos Hidalgo et al.   TRENDS IN CARDIOVASCULAR MEDICINE

Myosin binding protein-C phosphorylation is the principal mediator of protein kinase A effects on thick filament structure in myocardium

(2012) Brett A. Colson et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Structure, interactions and function of the N-terminus of cardiac myosin binding protein C (MyBP-C): who does what, with what, and to whom?

(2012) Mark Pfuhl et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Myosin head orientation: a structural determinant for the Frank-Starling relationship

(2011) Gerrie P. Farman et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

The interaction of Ca2+ with sarcomeric proteins: role in function and dysfunction of the heart

(2011) Hendrick E. D. J. ter Keurs   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Motion of myosin head domains during activation and force development in skeletal muscle

(2011) M. Reconditi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct visualization of myosin-binding protein C bridging myosin and actin filaments in intact muscle

(2011) P. K. Luther et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Myosin Binding Protein C Interaction with Actin

(2010) Inna N. Rybakova et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Myofilament length dependent activation

(2010) Pieter P. de Tombe et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Differential roles of regulatory light chain and myosin binding protein-C phosphorylations in the modulation of cardiac force development

(2010) Brett A. Colson et al.   JOURNAL OF PHYSIOLOGY-LONDON

Titin-based regulations of diastolic and systolic functions of mammalian cardiac muscle

(2009) Norio Fukuda et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The vertebrate muscle Z-disc: sarcomere anchor for structure and signalling

(2009) Pradeep K. Luther   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

Myosin ATP turnover rate is a mechanism involved in thermogenesis in resting skeletal muscle fibers

(2009) M. A. Stewart et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Visualization of cardiac muscle thin filaments and measurement of their lengths by electron tomography

(2008) Thomas Burgoyne et al.   CARDIOVASCULAR RESEARCH

Three-Dimensional Reconstruction of Tarantula Myosin Filaments Suggests How Phosphorylation May Regulate Myosin Activity

(2008) Lorenzo Alamo et al.   JOURNAL OF MOLECULAR BIOLOGY

Three-dimensional structure of vertebrate cardiac muscle myosin filaments

(2008) M. E. Zoghbi et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA