Length-dependent changes in contractile dynamics are blunted due to cardiac myosin binding protein-C ablation

In Situ Time-Resolved FRET Reveals Effects of Sarcomere Length on Cardiac Thin-Filament Activation

(2014) King-Lun Li et al.   BIOPHYSICAL JOURNAL

Kinetics of cardiac myosin isoforms in mouse myocardium are affected differently by presence of myosin binding protein-C

(2014) Bertrand C. W. Tanner et al.   JOURNAL OF MUSCLE RESEARCH AND CELL MOTILITY

The contribution of cardiac myosin binding protein-c Ser282 phosphorylation to the rate of force generation andin vivocardiac contractility

(2014) Kenneth S. Gresham et al.   JOURNAL OF PHYSIOLOGY-LONDON

Myosin-binding protein C displaces tropomyosin to activate cardiac thin filaments and governs their speed by an independent mechanism

(2014) Ji Young Mun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Impaired contractile function due to decreased cardiac myosin binding protein C content in the sarcomere

(2013) Y. Cheng et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Instability in the Central Region of Tropomyosin Modulates the Function of Its Overlapping Ends

(2013) Ranganath Mamidi et al.   BIOPHYSICAL JOURNAL

Perturbed Length-Dependent Activation in Human Hypertrophic Cardiomyopathy With Missense Sarcomeric Gene Mutations

(2013) Vasco Sequeira et al.   CIRCULATION RESEARCH

Divergent effects of α- and β-myosin heavy chain isoforms on the N terminus of rat cardiac troponin T

(2013) Ranganath Mamidi et al.   JOURNAL OF GENERAL PHYSIOLOGY

Deletion of 1–43 amino acids in cardiac myosin essential light chain blunts length dependency of Ca2+ sensitivity and cross-bridge detachment kinetics

(2012) John Jeshurun Michael et al.   AMERICAN JOURNAL OF PHYSIOLOGY-HEART AND CIRCULATORY PHYSIOLOGY

Cardiac Myosin Binding Protein C and Its Phosphorylation Regulate Multiple Steps in the Cross-Bridge Cycle of Muscle Contraction

(2012) Arthur T. Coulton et al.   BIOCHEMISTRY

The N-Terminal Extension of Cardiac Troponin T Stabilizes the Blocked State of Cardiac Thin Filament

(2012) Sampath K. Gollapudi et al.   BIOPHYSICAL JOURNAL

In Vivo Cardiac Myosin Binding Protein C Gene Transfer Rescues Myofilament Contractile Dysfunction in Cardiac Myosin Binding Protein C Null Mice

(2012) Sergei Merkulov et al.   Circulation-Heart Failure

Effects of R92 mutations in mouse cardiac troponin T are influenced by changes in myosin heavy chain isoform

(2012) Steven J. Ford et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

Identification of two new regions in the N-terminus of cardiac troponin T that have divergent effects on cardiac contractile function

(2012) Ranganath Mamidi et al.   JOURNAL OF PHYSIOLOGY-LONDON

Molecular Mechanics of Cardiac Myosin-Binding Protein C in Native Thick Filaments

(2012) M. J. Previs et al.   SCIENCE

Roles for Cardiac MyBP-C in Maintaining Myofilament Lattice Rigidity and Prolonging Myosin Cross-Bridge Lifetime

(2011) Bradley M. Palmer et al.   BIOPHYSICAL JOURNAL

Cardiac Myosin Binding Protein C Insufficiency Leads to Early Onset of Mechanical Dysfunction

(2011) Candida L. Desjardins et al.   Circulation-Cardiovascular Imaging

Contractile Dysfunction Irrespective of the Mutant Protein in Human Hypertrophic Cardiomyopathy With Normal Systolic Function

(2011) Sabine J. van Dijk et al.   Circulation-Heart Failure

Impact of myocyte strain on cardiac myofilament activation

(2011) Kenneth S. Campbell   PFLUGERS ARCHIV-EUROPEAN JOURNAL OF PHYSIOLOGY

The Role of Thin Filament Cooperativity in Cardiac Length-Dependent Calcium Activation

(2010) Gerrie P. Farman et al.   BIOPHYSICAL JOURNAL

Protein kinase A–induced myofilament desensitization to Ca2+as a result of phosphorylation of cardiac myosin–binding protein C

(2010) Peter P. Chen et al.   JOURNAL OF GENERAL PHYSIOLOGY

Model representation of the nonlinear step response in cardiac muscle

(2010) Steven J. Ford et al.   JOURNAL OF GENERAL PHYSIOLOGY

Myofilament length dependent activation

(2010) Pieter P. de Tombe et al.   JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY

The Myosin-binding Protein C Motif Binds to F-actin in a Phosphorylation-sensitive Manner

(2009) Justin F. Shaffer et al.   JOURNAL OF BIOLOGICAL CHEMISTRY