Temozolomide-Perillyl alcohol conjugate impairs Mitophagy flux by inducing lysosomal dysfunction in non-small cell lung Cancer cells and sensitizes them to irradiation

HMG-CoA reductase promotes protein prenylation and therefore is indispensible for T-cell survival

(2017) Sonja M Lacher et al.   Cell Death & Disease

Guidelines for the use and interpretation of assays for monitoring autophagy (3rd edition)

(2016) Daniel J Klionsky et al.   Autophagy

Mitochondrial dynamics altered by oxidative stress in cancer

(2016) Boyun Kim et al.   FREE RADICAL RESEARCH

Nutrient-regulated Phosphorylation of ATG13 Inhibits Starvation-induced Autophagy

(2016) Cindy Puente et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Flow Cytometry-Based Assessment of Mitophagy Using MitoTracker

(2016) Bin Xiao et al.   Frontiers in Cellular Neuroscience

Temozolomide-perillyl alcohol conjugate induced reactive oxygen species accumulation contributes to its cytotoxicity against non-small cell lung cancer

(2016) Xingguo Song et al.   Scientific Reports

Single-cell analysis challenges the connection between autophagy and senescence induced by DNA damage

(2015) Eduardo Cremonese Filippi-Chiela et al.   Autophagy

The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase

(2015) Marc M Schumacher et al.   eLife

NEO212, Temozolomide Conjugated to Perillyl Alcohol, Is a Novel Drug for Effective Treatment of a Broad Range of Temozolomide-Resistant Gliomas

(2014) H.-Y. Cho et al.   MOLECULAR CANCER THERAPEUTICS

A Novel Temozolomide-Perillyl Alcohol Conjugate Exhibits Superior Activity against Breast Cancer Cells In Vitro and Intracranial Triple-Negative Tumor Growth In Vivo

(2014) T. C. Chen et al.   MOLECULAR CANCER THERAPEUTICS

Cytoplasmic Irradiation Results in Mitochondrial Dysfunction and DRP1-Dependent Mitochondrial Fission

(2013) B. Zhang et al.   CANCER RESEARCH

Effects of ionizing radiation on mitochondria

(2013) Winnie Wai-Ying Kam et al.   FREE RADICAL BIOLOGY AND MEDICINE

At the end of the autophagic road: an emerging understanding of lysosomal functions in autophagy

(2013) Han-Ming Shen et al.   TRENDS IN BIOCHEMICAL SCIENCES

mTOR Signaling in Growth Control and Disease

(2012) Mathieu Laplante et al.   CELL

The pathways of mitophagy for quality control and clearance of mitochondria

(2012) G Ashrafi et al.   CELL DEATH AND DIFFERENTIATION

Nicotinamide-induced Mitophagy

(2012) So-young Jang et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Perillyl Alcohol for the Treatment of Temozolomide-Resistant Gliomas

(2012) H.-Y. Cho et al.   MOLECULAR CANCER THERAPEUTICS

Physiological Roles of Mitochondrial Reactive Oxygen Species

(2012) Laura A. Sena et al.   MOLECULAR CELL

Fiji: an open-source platform for biological-image analysis

(2012) Johannes Schindelin et al.   NATURE METHODS

Lysosomal Acidification Mechanisms

(2011) Joseph A. Mindell   Annual Review of Physiology

Induction of autophagy in temozolomide treated malignant gliomas

(2011) Manabu Natsumeda et al.   NEUROPATHOLOGY

Identification of the Switch in Early-to-Late Endosome Transition

(2010) Dmitry Poteryaev et al.   CELL

Rab7: Role of its protein interaction cascades in endo-lysosomal traffic

(2010) Tuanlao Wang et al.   CELLULAR SIGNALLING

Dual Role of 3-Methyladenine in Modulation of Autophagy via Different Temporal Patterns of Inhibition on Class I and III Phosphoinositide 3-Kinase

(2010) You-Tong Wu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Snapin-Regulated Late Endosomal Transport Is Critical for Efficient Autophagy-Lysosomal Function in Neurons

(2010) Qian Cai et al.   NEURON

Rab7: roles in membrane trafficking and disease

(2009) Ming Zhang et al.   BIOSCIENCE REPORTS

Parkin is recruited selectively to impaired mitochondria and promotes their autophagy

(2008) Derek Narendra et al.   JOURNAL OF CELL BIOLOGY