The prenyltransferase UBIAD1 is the target of geranylgeraniol in degradation of HMG CoA reductase

PCSK9 inhibition in LDL cholesterol reduction: Genetics and therapeutic implications of very low plasma lipoprotein levels

(2015) A. David Marais et al.   PHARMACOLOGY & THERAPEUTICS

Phenotype–Genotype Correlation in Patients With Schnyder Corneal Dystrophy

(2014) Anna K. Nowinska et al.   CORNEA

Sequential Actions of the AAA-ATPase Valosin-containing Protein (VCP)/p97 and the Proteasome 19 S Regulatory Particle in Sterol-accelerated, Endoplasmic Reticulum (ER)-associated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase

(2014) Lindsey L. Morris et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Structural Insights into Ubiquinone Biosynthesis in Membranes

(2014) W. Cheng et al.   SCIENCE

Structure of a Membrane-Embedded Prenyltransferase Homologous to UBIAD1

(2014) Hua Huang et al.   PLOS BIOLOGY

Structural Insights into Proteasome Activation by the 19S Regulatory Particle

(2013) Aaron Ehlinger et al.   BIOCHEMISTRY

Ubiad1 Is an Antioxidant Enzyme that Regulates eNOS Activity by CoQ10 Synthesis

(2013) Vera Mugoni et al.   CELL

Menadione (Vitamin K3) Is a Catabolic Product of Oral Phylloquinone (Vitamin K1) in the Intestine and a Circulating Precursor of Tissue Menaquinone-4 (Vitamin K2) in Rats

(2013) Yoshihisa Hirota et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Sterol-induced dislocation of 3-hydroxy-3-methylglutaryl coenzyme A reductase from membranes of permeabilized cells

(2013) Rania Elsabrouty et al.   MOLECULAR BIOLOGY OF THE CELL

A Novel Golgi Retention Signal RPWS for Tumor Suppressor UBIAD1

(2013) Xian Wang et al.   PLoS One

RNA-Guided Human Genome Engineering via Cas9

(2013) P. Mali et al.   SCIENCE

Multiplex Genome Engineering Using CRISPR/Cas Systems

(2013) L. Cong et al.   SCIENCE

Ablation of gp78 in Liver Improves Hyperlipidemia and Insulin Resistance by Inhibiting SREBP to Decrease Lipid Biosynthesis

(2012) Tong-Fei Liu et al.   Cell Metabolism

The UBIAD1 Prenyltransferase Links Menaquione-4 Synthesis to Cholesterol Metabolic Enzymes

(2012) Michael L. Nickerson et al.   HUMAN MUTATION

A promiscuous biotin ligase fusion protein identifies proximal and interacting proteins in mammalian cells

(2012) Kyle J. Roux et al.   JOURNAL OF CELL BIOLOGY

Ancient ubiquitous protein-1 mediates sterol-induced ubiquitination of 3-hydroxy-3-methylglutaryl CoA reductase in lipid droplet–associated endoplasmic reticulum membranes

(2012) Youngah Jo et al.   MOLECULAR BIOLOGY OF THE CELL

Membrane-associated Ubiquitin Ligase Complex Containing gp78 Mediates Sterol-accelerated Degradation of 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase

(2011) Youngah Jo et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Evolutionary Relationships of Microbial Aromatic Prenyltransferases

(2011) Tobias Bonitz et al.   PLoS One

Sterol-induced degradation of HMG CoA reductase depends on interplay of two Insigs and two ubiquitin ligases, gp78 and Trc8

(2011) Y. Jo et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Identification of UBIAD1 as a novel human menaquinone-4 biosynthetic enzyme

(2010) Kimie Nakagawa et al.   NATURE

UBIAD1 Mutation Alters a Mitochondrial Prenyltransferase to Cause Schnyder Corneal Dystrophy

(2010) Michael L. Nickerson et al.   PLoS One

Prenyl transfer to aromatic substrates: genetics and enzymology

(2009) Lutz Heide   CURRENT OPINION IN CHEMICAL BIOLOGY

Schnyder corneal dystrophy

(2009) Jayne S Weiss   CURRENT OPINION IN OPHTHALMOLOGY

Insig-mediated, Sterol-accelerated Degradation of the Membrane Domain of Hamster 3-Hydroxy-3-methylglutaryl-coenzyme A Reductase in Insect Cells

(2009) Andrew D. Nguyen et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Fast and Sensitive Colloidal Coomassie G-250 Staining for Proteins in Polyacrylamide Gels

(2009) Nadine Dyballa et al.   Jove-Journal of Visualized Experiments

The Discovery of Statins

(2008) Thomas P. Stossel   CELL

A Structural Model of the Membrane-Bound Aromatic Prenyltransferase UbiA fromE. coli

(2008) Lars Bräuer et al.   CHEMBIOCHEM