A carnosine analog mitigates metabolic disorders of obesity by reducing carbonyl stress
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Title
A carnosine analog mitigates metabolic disorders of obesity by reducing carbonyl stress
Authors
Keywords
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Journal
JOURNAL OF CLINICAL INVESTIGATION
Volume 128, Issue 12, Pages 5280-5293
Publisher
American Society for Clinical Investigation
Online
2018-09-19
DOI
10.1172/jci94307
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Note: Only part of the references are listed.- Regulatory landscape of AGE-RAGE-oxidative stress axis and its modulation by PPARγ activation in high fructose diet-induced metabolic syndrome
- (2017) Luca Cannizzaro et al. Nutrition & Metabolism
- Nonalcoholic Fatty Liver Disease: Pathogenesis and Disease Spectrum
- (2016) Timothy Hardy et al. Annual Review of Pathology-Mechanisms of Disease
- Reactivity, Selectivity, and Reaction Mechanisms of Aminoguanidine, Hydralazine, Pyridoxamine, and Carnosine as Sequestering Agents of Reactive Carbonyl Species: A Comparative Study
- (2016) Mara Colzani et al. ChemMedChem
- Computational approaches in the rational design of improved carbonyl quenchers: focus on histidine containing dipeptides
- (2016) Giulio Vistoli et al. Future Medicinal Chemistry
- Management of NAFLD: a stage-based approach
- (2016) Mary E. Rinella et al. Nature Reviews Gastroenterology & Hepatology
- Effects of carnosine supplementation on glucose metabolism: Pilot clinical trial
- (2016) Barbora de Courten et al. Obesity
- Peroxidation of polyunsaturated fatty acids by lipoxygenases drives ferroptosis
- (2016) Wan Seok Yang et al. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA
- Glutathione peroxidase 4 and vitamin E cooperatively prevent hepatocellular degeneration
- (2016) Bradley A. Carlson et al. Redox Biology
- Structural Elucidation of a Carnosine-Acrolein Adduct and its Quantification in Human Urine Samples
- (2016) Vanderson S. Bispo et al. Scientific Reports
- A carnosine intervention study in overweight human volunteers: bioavailability and reactive carbonyl species sequestering effect
- (2016) Luca Regazzoni et al. Scientific Reports
- Advanced Glycation End-Products: A Biological Consequence of Lifestyle Contributing to Cancer Disparity
- (2015) D. P. Turner CANCER RESEARCH
- AGEs and chronic subclinical inflammation in diabetes: disorders of immune system
- (2015) Hang Hu et al. DIABETES-METABOLISM RESEARCH AND REVIEWS
- Beta cell response to nutrient overload involves phospholipid remodelling and lipid peroxidation
- (2015) Guy Cohen et al. DIABETOLOGIA
- Elevated Serum Advanced Glycation Endproducts in Obese Indicate Risk for the Metabolic Syndrome: A Link Between Healthy and Unhealthy Obesity?
- (2015) Jaime Uribarri et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Immune activation caused by vascular oxidation promotes fibrosis and hypertension
- (2015) Jing Wu et al. JOURNAL OF CLINICAL INVESTIGATION
- Excessive caloric intake acutely causes oxidative stress, GLUT4 carbonylation, and insulin resistance in healthy men
- (2015) Guenther Boden et al. Science Translational Medicine
- Dietary Advanced Glycation End Products and Their Role in Health and Disease
- (2015) Jaime Uribarri et al. Advances in Nutrition
- Obesity in a model of gpx4 haploinsufficiency uncovers a causal role for lipid-derived aldehydes in human metabolic disease and cardiomyopathy
- (2015) Lalage A. Katunga et al. Molecular Metabolism
- Novel molecular approaches for improving enzymatic and nonenzymatic detoxification of 4-hydroxynonenal: toward the discovery of a novel class of bioactive compounds
- (2014) Giancarlo Aldini et al. FREE RADICAL BIOLOGY AND MEDICINE
- Association of Genetic Polymorphisms for Glutathione Peroxidase Genes with Obesity in Spanish Children
- (2014) Azahara I. Rupérez et al. Journal of Nutrigenetics and Nutrigenomics
- A novel high resolution MS approach for the screening of 4-hydroxy-trans-2-nonenal sequestering agents
- (2014) Mara Colzani et al. JOURNAL OF PHARMACEUTICAL AND BIOMEDICAL ANALYSIS
- Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice
- (2014) Jose Pedro Friedmann Angeli et al. NATURE CELL BIOLOGY
- Effect of advanced glycation end product intake on inflammation and aging: a systematic review
- (2014) Katrien Van Puyvelde et al. NUTRITION REVIEWS
- Overexpression of glutathione peroxidase 4 prevents β-cell dysfunction induced by prolonged elevation of lipids in vivo
- (2013) Khajag Koulajian et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Dietary Carnosine Prevents Early Atherosclerotic Lesion Formation in Apolipoprotein E–Null Mice
- (2013) Oleg A. Barski et al. ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY
- Supplementation with carnosine decreases plasma triglycerides and modulates atherosclerotic plaque composition in diabetic apo E−/− mice
- (2013) Bronwyn E. Brown et al. ATHEROSCLEROSIS
- Combined Deficiency in Glutathione Peroxidase 4 and Vitamin E Causes Multiorgan Thrombus Formation and Early Death in Mice
- (2013) Markus Wortmann et al. CIRCULATION RESEARCH
- Glutathionylated Lipid Aldehydes Are Products of Adipocyte Oxidative Stress and Activators of Macrophage Inflammation
- (2013) B. I. Frohnert et al. DIABETES
- Advanced Glycation Endproducts in Diabetes and Diabetic Complications
- (2013) Helen Vlassara et al. ENDOCRINOLOGY AND METABOLISM CLINICS OF NORTH AMERICA
- Signaling properties of 4-hydroxyalkenals formed by lipid peroxidation in diabetes
- (2013) Guy Cohen et al. FREE RADICAL BIOLOGY AND MEDICINE
- Molecular strategies to prevent, inhibit, and degrade advanced glycoxidation and advanced lipoxidation end products
- (2013) Giancarlo Aldini et al. FREE RADICAL RESEARCH
- Role of Aldose Reductase in the Metabolism and Detoxification of Carnosine-Acrolein Conjugates
- (2013) Shahid P. Baba et al. JOURNAL OF BIOLOGICAL CHEMISTRY
- Dietary glycotoxins exacerbate progression of experimental fatty liver disease
- (2013) Christopher Leung et al. JOURNAL OF HEPATOLOGY
- Novel role for thioredoxin reductase-2 in mitochondrial redox adaptations to obesogenic diet and exercise in heart and skeletal muscle
- (2013) Kelsey H. Fisher-Wellman et al. JOURNAL OF PHYSIOLOGY-LONDON
- Oxidative stress and protein carbonylation in adipose tissue — Implications for insulin resistance and diabetes mellitus
- (2013) Tatjana Ruskovska et al. Journal of Proteomics
- The single-nucleotide polymorphism (GPX4c718t) in the glutathione peroxidase 4 gene influences endothelial cell function: Interaction with selenium and fatty acids
- (2013) Lynne K. Crosley et al. MOLECULAR NUTRITION & FOOD RESEARCH
- Physiology and Pathophysiology of Carnosine
- (2013) Alexander A. Boldyrev et al. PHYSIOLOGICAL REVIEWS
- Increased 4-Hydroxynonenal Formation Contributes to Obesity-Related Lipolytic Activation in Adipocytes
- (2013) Ximei Zhang et al. PLoS One
- The lipid peroxidation end-product and oxidant 4-hydroxynonenal induces insulin resistance in rat slow-twitch skeletal muscle
- (2013) Mujalin Prasannarong et al. ARCHIVES OF PHYSIOLOGY AND BIOCHEMISTRY
- Role of l-carnosine in the control of blood glucose, blood pressure, thermogenesis, and lipolysis by autonomic nerves in rats: involvement of the circadian clock and histamine
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- Skeletal Muscle Lipid Peroxidation and Insulin Resistance in Humans
- (2012) Katherine H. Ingram et al. JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM
- Design, Synthesis, ADME Properties, and Pharmacological Activities of β-Alanyl-D-histidine (D-Carnosine) Prodrugs with Improved Bioavailability
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- The C718T polymorphism in the 3′-untranslated region of glutathione peroxidase-4 gene is a predictor of cerebral stroke in patients with essential hypertension
- (2011) Alexey V Polonikov et al. HYPERTENSION RESEARCH
- Increased Adipose Protein Carbonylation in Human Obesity
- (2011) Brigitte I. Frohnert et al. Obesity
- Potential New Therapeutic Agents for Diabetic Kidney Disease
- (2010) Faruk Turgut et al. AMERICAN JOURNAL OF KIDNEY DISEASES
- Signaling and cytotoxic functions of 4-hydroxyalkenals
- (2010) Yael Riahi et al. AMERICAN JOURNAL OF PHYSIOLOGY-ENDOCRINOLOGY AND METABOLISM
- Meta-analysis: Natural history of non-alcoholic fatty liver disease (NAFLD) and diagnostic accuracy of non-invasive tests for liver disease severity
- (2010) Giovanni Musso et al. ANNALS OF MEDICINE
- Pathological aspects of lipid peroxidation
- (2010) Anne Negre-Salvayre et al. FREE RADICAL RESEARCH
- The carbonyl scavenger carnosine ameliorates dyslipidaemia and renal function in Zucker obese rats
- (2010) Giancarlo Aldini et al. JOURNAL OF CELLULAR AND MOLECULAR MEDICINE
- Synthesis, Physicochemical Characterization, and Biological Activities of New Carnosine Derivatives Stable in Human Serum As Potential Neuroprotective Agents
- (2010) Massimo Bertinaria et al. JOURNAL OF MEDICINAL CHEMISTRY
- N-Acetylcarnosine Lubricant Eyedrops Possess All-In-One Universal Antioxidant Protective Effects of L-Carnosine in Aqueous and Lipid Membrane Environments, Aldehyde Scavenging, and Transglycation Activities Inherent to Cataracts: A Clinical Study of the New Vision-Saving Drug N-Acetylcarnosine Eyedrop Therapy in a Database Population of Over 50,500 Patients
- (2009) Mark A Babizhayev et al. AMERICAN JOURNAL OF THERAPEUTICS
- Transgenic mouse models for the vital selenoenzymes cytosolic thioredoxin reductase, mitochondrial thioredoxin reductase and glutathione peroxidase 4
- (2009) Marcus Conrad BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS
- Biological Activity of Novel Synthetic Derivatives of Carnosine
- (2009) S. L. Stvolinsky et al. CELLULAR AND MOLECULAR NEUROBIOLOGY
- Glutathione peroxidase 4 differentially regulates the release of apoptogenic proteins from mitochondria
- (2009) Hanyu Liang et al. FREE RADICAL BIOLOGY AND MEDICINE
- Lipid peroxidation: Physiological levels and dual biological effects
- (2009) Etsuo Niki FREE RADICAL BIOLOGY AND MEDICINE
- Substrate-Specific Derangements in Mitochondrial Metabolism and Redox Balance in the Atrium of the Type 2 Diabetic Human Heart
- (2009) Ethan J. Anderson et al. JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY
- Glutathione Peroxidase 4 Senses and Translates Oxidative Stress into 12/15-Lipoxygenase Dependent- and AIF-Mediated Cell Death
- (2008) Alexander Seiler et al. Cell Metabolism
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