Exosomes derived from acute myeloid leukemia cells promote chemoresistance by enhancing glycolysis-mediated vascular remodeling

Inhibition of Endosteal Vascular Niche Remodeling Rescues Hematopoietic Stem Cell Loss in AML

(2018) Delfim Duarte et al.   Cell Stem Cell

Shedding light on the cell biology of extracellular vesicles

(2018) Guillaume van Niel et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Endothelial Cell Metabolism

(2018) Guy Eelen et al.   PHYSIOLOGICAL REVIEWS

Targeting angiogenic metabolism in disease

(2018) Xuri Li et al.   SCIENCE

The urokinase plasminogen activator system components are regulated by vascular endothelial growth factor D in bovine oviduct

(2018) Daniela C. García et al.   ZYGOTE

Acute myeloid leukaemia

(2018) Nicholas J Short et al.   LANCET

Exosome-Derived miR-130a Activates Angiogenesis in Gastric Cancer by Targeting C-MYB in Vascular Endothelial Cells

(2018) Haiou Yang et al.   MOLECULAR THERAPY

Homoharringtonine enhances bortezomib antimyeloma activity in myeloma cells adhesion to bone marrow stromal cells and in SCID mouse xenografts

(2017) Ping Chen et al.   LEUKEMIA RESEARCH

Acute myeloid leukaemia disrupts endogenous myelo-erythropoiesis by compromising the adipocyte bone marrow niche

(2017) Allison L. Boyd et al.   NATURE CELL BIOLOGY

Metabolic reprogramming of bone marrow stromal cells by leukemic extracellular vesicles in acute lymphoblastic leukemia

(2016) S. M. Johnson et al.   BLOOD

Protective mitochondrial transfer from bone marrow stromal cells to acute myeloid leukemic cells during chemotherapy

(2016) R. Moschoi et al.   BLOOD

Induction of Multidrug Resistance of Acute Myeloid Leukemia Cells by Cocultured Stromal Cells via Upregulation of the PI3K/Akt Signaling Pathway

(2016) Ping Chen et al.   ONCOLOGY RESEARCH

Glycolytic regulation of cell rearrangement in angiogenesis

(2016) Bert Cruys et al.   Nature Communications

PML–RARa modulates the vascular signature of extracellular vesicles released by acute promyelocytic leukemia cells

(2015) Yi Fang et al.   ANGIOGENESIS

Exosomes released by chronic lymphocytic leukemia cells induce the transition of stromal cells into cancer-associated fibroblasts

(2015) J. Paggetti et al.   BLOOD

Making sense of hematopoietic stem cell niches

(2015) P. E. Boulais et al.   BLOOD

An update of current treatments for adult acute myeloid leukemia

(2015) H. Dombret et al.   BLOOD

Exosomes in cancer: small particle, big player

(2015) Xu Zhang et al.   Journal of Hematology & Oncology

Functional inhibition of mesenchymal stromal cells in acute myeloid leukemia

(2015) S Geyh et al.   LEUKEMIA

Metabolic Reprogramming of Cancer-Associated Fibroblasts by IDH3α Downregulation

(2015) Daoxiang Zhang et al.   Cell Reports

VEGF-VEGFR Signals in Health and Disease

(2014) Masabumi Shibuya   Biomolecules & Therapeutics

Inhibition of leukemia cell engraftment and disease progression in mice by osteoblasts

(2014) M. Krevvata et al.   BLOOD

Microvesicles secreted from human multiple myeloma cells promote angiogenesis

(2013) Yan Liu et al.   ACTA PHARMACOLOGICA SINICA

Acute myeloid leukemia creates an arginase-dependent immunosuppressive microenvironment

(2013) F. Mussai et al.   BLOOD

Exosomes Derived from Hypoxic Leukemia Cells Enhance Tube Formation in Endothelial Cells

(2013) Hiroko Tadokoro et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Accessories to the Crime: Functions of Cells Recruited to the Tumor Microenvironment

(2012) Douglas Hanahan et al.   CANCER CELL

Vascular endothelial growth factor signaling in acute myeloid leukemia

(2012) Kim R. Kampen et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

Leukemia cell to endothelial cell communication via exosomal miRNAs

(2012) T Umezu et al.   ONCOGENE

Exosomes released by K562 chronic myeloid leukemia cells promote angiogenesis in a src-dependent fashion

(2011) Marco Mineo et al.   ANGIOGENESIS

Signal transduction in vasculogenesis and developmental angiogenesis

(2011) Sunita Patel-Hett et al.   INTERNATIONAL JOURNAL OF DEVELOPMENTAL BIOLOGY

Contribution of bone microenvironment to leukemogenesis and leukemia progression

(2009) F Ayala et al.   LEUKEMIA

Understanding the Warburg Effect: The Metabolic Requirements of Cell Proliferation

(2009) M. G. Vander Heiden et al.   SCIENCE

Bone marrow angiogenesis magnetic resonance imaging in patients with acute myeloid leukemia: peak enhancement ratio is an independent predictor for overall survival

(2008) T. T.-F. Shih et al.   BLOOD

The Bone Marrow Microenvironment as a Tumor Sanctuary and Contributor to Drug Resistance

(2008) M. B. Meads et al.   CLINICAL CANCER RESEARCH