Role of miR‐486‐5p in regulating renal cell carcinoma cell proliferation and apoptosis via TGF‐β–activated kinase 1

MicroRNAs Associated with Von Hippel–Lindau Pathway in Renal Cell Carcinoma: A Comprehensive Review

(2017) Lisa-Maria Schanza et al.   INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES

New treatment options for metastatic renal cell carcinoma with prior anti-angiogenesis therapy

(2017) Kevin Zarrabi et al.   Journal of Hematology & Oncology

miR-486-5p inhibits cell growth of papillary thyroid carcinoma by targeting fibrillin-1

(2016) Xinfeng Ma et al.   BIOMEDICINE & PHARMACOTHERAPY

Inhibition of BMP and of TGFβ receptors downregulates expression of XIAP and TAK1 leading to lung cancer cell death

(2016) Dave J. Augeri et al.   Molecular Cancer

Tumor Associated Macrophages in Kidney Cancer

(2016) Olga V. Kovaleva et al.   Analytical Cellular Pathology

miR-486-5p suppresses prostate cancer metastasis by targeting Snail and regulating epithelial–mesenchymal transition

(2016) Xiaoguang Zhang et al.   OncoTargets and Therapy

Downregulated miR-486-5p acts as a tumor suppressor in esophageal squamous cell carcinoma

(2016) Yunfeng Yi et al.   Experimental and Therapeutic Medicine

MicroRNA-486-5p enhances hepatocellular carcinoma tumor suppression through repression of IGF-1R and its downstream mTOR, STAT3 and c-Myc

(2016) Rana Ahmed Youness et al.   Oncology Letters

Direct repression of the oncogene CDK4 by the tumor suppressor miR-486-5p in non-small cell lung cancer

(2016) Yang Shao et al.   Oncotarget

MiR-377 targets E2F3 and alters the NF-kB signaling pathway through MAP3K7 in malignant melanoma

(2015) Liron Zehavi et al.   Molecular Cancer

MUC1-C activates the TAK1 inflammatory pathway in colon cancer

(2015) H Takahashi et al.   ONCOGENE

miR-146b-5p functions as a tumor suppressor by targeting TRAF6 and predicts the prognosis of human gliomas

(2015) Jing Liu et al.   Oncotarget

MicroRNAs as prognostic molecular signatures in renal cell carcinoma: a systematic review and meta-analysis

(2015) Liangyou Gu et al.   Oncotarget

USP18 negatively regulates NF-κB signaling by targeting TAK1 and NEMO for deubiquitination through distinct mechanisms

(2015) Zhifen Yang et al.   Scientific Reports

Expression and Prognostic Value of miR-486-5p in Patients with Gastric Adenocarcinoma

(2015) Hui Chen et al.   PLoS One

Elevated TAK1 augments tumor growth and metastatic capacities of ovarian cancer cells through activation of NF-κB signaling

(2015) Patty C.H. Cai et al.   Oncotarget

The TAK1-NF- B axis as therapeutic target for AML

(2014) M. C. J. Bosman et al.   BLOOD

MicroRNA-486 regulates normal erythropoiesis and enhances growth and modulates drug response in CML progenitors

(2014) L.-S. Wang et al.   BLOOD

MicroRNA-486-5p, which is downregulated in hepatocellular carcinoma, suppresses tumor growth by targeting PIK3R1

(2014) Xin-Ping Huang et al.   FEBS Journal

TAK1-mediated autophagy and fatty acid oxidation prevent hepatosteatosis and tumorigenesis

(2014) Sayaka Inokuchi-Shimizu et al.   JOURNAL OF CLINICAL INVESTIGATION

TAK1 regulates hepatic cell survival and carcinogenesis

(2014) Yoon Seok Roh et al.   JOURNAL OF GASTROENTEROLOGY

Discovery of Type II Inhibitors of TGFβ-Activated Kinase 1 (TAK1) and Mitogen-Activated Protein Kinase Kinase Kinase Kinase 2 (MAP4K2)

(2014) Li Tan et al.   JOURNAL OF MEDICINAL CHEMISTRY

MicroRNA-26b suppresses the NF-κB signaling and enhances the chemosensitivity of hepatocellular carcinoma cells by targeting TAK1 and TAB3

(2014) Na Zhao et al.   Molecular Cancer

Pim-1 kinase is a target of miR-486-5p and eukaryotic translation initiation factor 4E, and plays a critical role in lung cancer

(2014) Wenshuai Pang et al.   Molecular Cancer

MicroRNA-486-5p targeting PIM-1 suppresses cell proliferation in breast cancer cells

(2014) Guoqiang Zhang et al.   TUMOR BIOLOGY

miR-155 Regulates Immune Modulatory Properties of Mesenchymal Stem Cells by Targeting TAK1-binding Protein 2

(2013) Chunliang Xu et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Downregulation of miR-486-5p contributes to tumor progression and metastasis by targeting protumorigenic ARHGAP5 in lung cancer

(2013) J Wang et al.   ONCOGENE

Loss of TAK1 increases cell traction force in a ROS-dependent manner to drive epithelial–mesenchymal transition of cancer cells

(2013) C R I Lam et al.   Cell Death & Disease

Tumor-Associated Macrophages Mediate Immunosuppression in the Renal Cancer Microenvironment by Activating the 15-Lipoxygenase-2 Pathway

(2011) I. Daurkin et al.   CANCER RESEARCH