MicroRNA-486-5p, which is downregulated in hepatocellular carcinoma, suppresses tumor growth by targeting PIK3R1

Downregulation of miR-486-5p contributes to tumor progression and metastasis by targeting protumorigenic ARHGAP5 in lung cancer

(2013) J Wang et al.   ONCOGENE

TLS-CHOP represses miR-486 expression, inducing upregulation of a metastasis regulator PAI-1 in human myxoid liposarcoma

(2012) Nariso Borjigin et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

MiR-124 suppresses cell proliferation in hepatocellular carcinoma by targeting PIK3CA

(2012) Qingbo Lang et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Meta-analysis of microRNA expression in lung cancer

(2012) Urmo Võsa et al.   INTERNATIONAL JOURNAL OF CANCER

Heterogeneous nuclear ribonucleoprotein K (hnRNP K) is a tissue biomarker for detection of early Hepatocellular carcinoma in patients with cirrhosis

(2012) Yantong Guo et al.   Journal of Hematology & Oncology

Modulation of the Osteosarcoma Expression Phenotype by MicroRNAs

(2012) Heidi M. Namløs et al.   PLoS One

Diagnosis of lung cancer in individuals with solitary pulmonary nodules by plasma microRNA biomarkers

(2011) Jun Shen et al.   BMC CANCER

Global cancer statistics

(2011) Ahmedin Jemal et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Identification of miRNomes in Human Liver and Hepatocellular Carcinoma Reveals miR-199a/b-3p as Therapeutic Target for Hepatocellular Carcinoma

(2011) Jin Hou et al.   CANCER CELL

PIK3R1 (p85 ) Is Somatically Mutated at High Frequency in Primary Endometrial Cancer

(2011) M. E. Urick et al.   CANCER RESEARCH

Genomic Loss of miR-486 Regulates Tumor Progression and the OLFM4 Antiapoptotic Factor in Gastric Cancer

(2011) H.-K. Oh et al.   CLINICAL CANCER RESEARCH

Risk Factors, Clinical Features, and Prognosis of the Hepatocellular Carcinoma with Peritoneal Metastasis

(2011) Min-Sun Kwak et al.   DIGESTIVE DISEASES AND SCIENCES

MicroRNA-29b suppresses tumor angiogenesis, invasion, and metastasis by regulating matrix metalloproteinase 2 expression

(2011) Jian-Hong Fang et al.   HEPATOLOGY

Non-Smad Transforming Growth Factor-β Signaling Regulated by Focal Adhesion Kinase Binding the p85 Subunit of Phosphatidylinositol 3-Kinase

(2011) Min Hong et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

MicroRNA-99a Inhibits Hepatocellular Carcinoma Growth and Correlates with Prognosis of Patients with Hepatocellular Carcinoma

(2011) Dong Li et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

High Frequency of PIK3R1 and PIK3R2 Mutations in Endometrial Cancer Elucidates a Novel Mechanism for Regulation of PTEN Protein Stability

(2011) Lydia W.T. Cheung et al.   Cancer Discovery

Regulation of mRNA Translation and Stability by microRNAs

(2010) Marc Robert Fabian et al.   Annual Review of Biochemistry

microRNA-22, downregulated in hepatocellular carcinoma and correlated with prognosis, suppresses cell proliferation and tumourigenicity

(2010) J Zhang et al.   BRITISH JOURNAL OF CANCER

The Phosphoinositide 3-Kinase Regulatory Subunit p85  Can Exert Tumor Suppressor Properties through Negative Regulation of Growth Factor Signaling

(2010) C. M. Taniguchi et al.   CANCER RESEARCH

Genetic variations of the PI3K-AKT-mTOR pathway and clinical outcome in muscle invasive and metastatic bladder cancer patients

(2010) M. Chen et al.   CARCINOGENESIS

Hsa-let-7g inhibits proliferation of hepatocellular carcinoma cells by downregulation of c-Myc and upregulation of p16INK4A

(2010) Fei-Fei Lan et al.   INTERNATIONAL JOURNAL OF CANCER

Emerging roles of microRNA in the intracellular signaling networks of hepatocellular carcinoma

(2010) Priscilla T-Y Law et al.   JOURNAL OF GASTROENTEROLOGY AND HEPATOLOGY

The clinical potential of microRNAs

(2010) Anuradha Budhu et al.   Journal of Hematology & Oncology

The role of signaling pathways in the development and treatment of hepatocellular carcinoma

(2010) S Whittaker et al.   ONCOGENE

Cancer-derived mutations in the regulatory subunit p85  of phosphoinositide 3-kinase function through the catalytic subunit p110 

(2010) M. Sun et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Direct positive regulation of PTEN by the p85 subunit of phosphatidylinositol 3-kinase

(2010) R. B. Chagpar et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Involvement of CD40 Targeting miR-224 and miR-486 on the Progression of Pancreatic Ductal Adenocarcinomas

(2009) Soeren Torge Mees et al.   ANNALS OF SURGICAL ONCOLOGY

Somatic Mutations in p85α Promote Tumorigenesis through Class IA PI3K Activation

(2009) Bijay S. Jaiswal et al.   CANCER CELL

MicroRNA-101, Down-regulated in Hepatocellular Carcinoma, Promotes Apoptosis and Suppresses Tumorigenicity

(2009) H. Su et al.   CANCER RESEARCH

Differential diagnosis of hepatocellular carcinoma from metastatic tumors in the liver using microRNA expression

(2009) Iris Barshack et al.   INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY

A novel microRNA targeting HDAC5 regulates osteoblast differentiation in mice and contributes to primary osteoporosis in humans

(2009) Hui Li et al.   JOURNAL OF CLINICAL INVESTIGATION

Hepatocellular Carcinoma Incidence, Mortality, and Survival Trends in the United States From 1975 to 2005

(2009) Sean F. Altekruse et al.   JOURNAL OF CLINICAL ONCOLOGY

MicroRNA-146a Feedback Inhibits RIG-I-Dependent Type I IFN Production in Macrophages by Targeting TRAF6, IRAK1, and IRAK2

(2009) J. Hou et al.   JOURNAL OF IMMUNOLOGY

Novel Rank-Based Statistical Methods Reveal MicroRNAs with Differential Expression in Multiple Cancer Types

(2009) Roy Navon et al.   PLoS One

Identification of metastasis-related microRNAs in hepatocellular carcinoma

(2008) Anuradha Budhu et al.   HEPATOLOGY

Widespread changes in protein synthesis induced by microRNAs

(2008) Matthias Selbach et al.   NATURE

Class I PI3K in oncogenic cellular transformation

(2008) L Zhao et al.   ONCOGENE