Knockdown GREM1 suppresses cell growth, angiogenesis, and epithelial-mesenchymal transition in colon cancer

Bone morphogenetic protein and Notch signalling crosstalk in poor-prognosis, mesenchymal-subtype colorectal cancer

(2017) Shazia Irshad et al.   JOURNAL OF PATHOLOGY

Gremlin1 preferentially binds to bone morphogenetic protein-2 (BMP-2) and BMP-4 over BMP-7

(2015) Rachel H. Church et al.   BIOCHEMICAL JOURNAL

Gremlin 1 Identifies a Skeletal Stem Cell with Bone, Cartilage, and Reticular Stromal Potential

(2015) Daniel L. Worthley et al.   CELL

TNF-αand TGF-β1 regulate Syndecan-4 expression in nucleus pulposus cells: role of the mitogen-activated protein kinase and NF-κB pathways

(2015) Hao Yang et al.   CONNECTIVE TISSUE RESEARCH

Clinical significance of Gremlin 1 in cervical cancer and its effects on cancer stem cell maintenance

(2015) MASAKAZU SATO et al.   ONCOLOGY REPORTS

BMP pathway suppression is an early event in inflammation-driven colon neoplasmatogenesis of uPA-deficient mice

(2015) George S. Karagiannis et al.   TUMOR BIOLOGY

The BMP pathway either enhances or inhibits the Wnt pathway depending on the SMAD4 and p53 status in CRC

(2014) P W Voorneveld et al.   BRITISH JOURNAL OF CANCER

Colorectal cancer statistics, 2014

(2014) Rebecca Siegel et al.   CA-A CANCER JOURNAL FOR CLINICIANS

Loss of SMAD4 Alters BMP Signaling to Promote Colorectal Cancer Cell Metastasis via Activation of Rho and ROCK

(2014) Philip W. Voorneveld et al.   GASTROENTEROLOGY

Glioma cancer stem cells secrete Gremlin1 to promote their maintenance within the tumor hierarchy

(2014) K. Yan et al.   GENES & DEVELOPMENT

Aberrant epithelial GREM1 expression initiates colonic tumorigenesis from cells outside the stem cell niche

(2014) Hayley Davis et al.   NATURE MEDICINE

Targeting EMT in cancer: opportunities for pharmacological intervention

(2014) Felicity M. Davis et al.   TRENDS IN PHARMACOLOGICAL SCIENCES

The Hippo pathway: regulators and regulations

(2013) F.-X. Yu et al.   GENES & DEVELOPMENT

Developmental pathways in colon cancer

(2012) Fred E. Bertrand et al.   CELL CYCLE

Expression of gremlin 1 correlates with increased angiogenesis and progression-free survival in patients with pancreatic neuroendocrine tumors

(2012) Ming-Huang Chen et al.   JOURNAL OF GASTROENTEROLOGY

Gremlin is Overexpressed in Lung Adenocarcinoma and Increases Cell Growth and Proliferation in Normal Lung Cells

(2012) Michael S. Mulvihill et al.   PLoS One

Orai1 and CRAC Channel Dependence of VEGF-Activated Ca 2+ Entry and Endothelial Tube Formation

(2011) Jing Li et al.   CIRCULATION RESEARCH

Molecular mechanisms and clinical applications of angiogenesis

(2011) Peter Carmeliet et al.   NATURE

Multiple Common Susceptibility Variants near BMP Pathway Loci GREM1, BMP4, and BMP2 Explain Part of the Missing Heritability of Colorectal Cancer

(2011) Ian P. M. Tomlinson et al.   PLoS Genetics

Gremlin is a novel agonist of the major proangiogenic receptor VEGFR2

(2010) S. Mitola et al.   BLOOD

EMT, cancer stem cells and drug resistance: an emerging axis of evil in the war on cancer

(2010) A Singh et al.   ONCOGENE

Extracellular BMP-antagonist regulation in development and disease: tied up in knots

(2010) David W. Walsh et al.   TRENDS IN CELL BIOLOGY

Epithelial-Mesenchymal Transition: At the Crossroads of Development and Tumor Metastasis

(2008) Jing Yang et al.   DEVELOPMENTAL CELL

Development and validation of a real-time PCR assay specifically detecting human papillomavirus 52 using the Roche LightCycler® 480 system

(2007) Matthew P. Stevens et al.   JOURNAL OF VIROLOGICAL METHODS