HGF-induced migration depends on the PI(3,4,5)P3-binding microexon-spliced variant of the Arf6 exchange factor cytohesin-1

KIBRA (WWC1) Is a Metastasis Suppressor Gene Affected by Chromosome 5q Loss in Triple-Negative Breast Cancer

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A module for Rac temporal signal integration revealed with optogenetics

(2017) Brian R. Graziano et al.   JOURNAL OF CELL BIOLOGY

PTEN Regulates PI(3,4)P 2 Signaling Downstream of Class I PI3K

(2017) Mouhannad Malek et al.   MOLECULAR CELL

Alternative splicing as a regulator of development and tissue identity

(2017) Francisco E. Baralle et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Microexons: discovery, regulation, and function

(2017) Dmytro Ustianenko et al.   Wiley Interdisciplinary Reviews-RNA

ARF6 Is an Actionable Node that Orchestrates Oncogenic GNAQ Signaling in Uveal Melanoma

(2016) Jae Hyuk Yoo et al.   CANCER CELL

Distinct subcellular localization of alternative splicing variants of EFA6D, a guanine nucleotide exchange factor for Arf6, in the mouse brain

(2016) Masahiro Fukaya et al.   JOURNAL OF COMPARATIVE NEUROLOGY

Regulation of Cell Migration and β1 Integrin Trafficking by the Endosomal Adaptor GGA3

(2016) Colin D. H. Ratcliffe et al.   TRAFFIC

Inhibition of WAVE Regulatory Complex Activation by a Bacterial Virulence Effector Counteracts Pathogen Phagocytosis

(2016) Daniel Humphreys et al.   Cell Reports

The N2-Src neuronal splice variant of C-Src has altered SH3 domain ligand specificity and a higher constitutive activity than N1-Src

(2015) Sarah Keenan et al.   FEBS LETTERS

Arf6 regulates tumour angiogenesis and growth through HGF-induced endothelial β1 integrin recycling

(2015) Tsunaki Hongu et al.   Nature Communications

A single-nucleotide exon found in Arabidopsis

(2015) Lei Guo et al.   Scientific Reports

Abl Kinases Regulate HGF/Met Signaling Required for Epithelial Cell Scattering, Tubulogenesis and Motility

(2015) Ran Li et al.   PLoS One

A Highly Conserved Program of Neuronal Microexons Is Misregulated in Autistic Brains

(2014) Manuel Irimia et al.   CELL

A RAB5/RAB4 recycling circuitry induces a proteolytic invasive program and promotes tumor dissemination

(2014) Emanuela Frittoli et al.   JOURNAL OF CELL BIOLOGY

Improved vectors and genome-wide libraries for CRISPR screening

(2014) Neville E Sanjana et al.   NATURE METHODS

Easy quantitative assessment of genome editing by sequence trace decomposition

(2014) Eva K. Brinkman et al.   NUCLEIC ACIDS RESEARCH

Clathrin-Independent Pathways of Endocytosis

(2014) S. Mayor et al.   Cold Spring Harbor Perspectives in Biology

Receptor tyrosine kinase c-Met controls the cytoskeleton from different endosomes via different pathways

(2014) Ludovic Ménard et al.   Nature Communications

The cytohesin paralog Sec7 of Dictyostelium discoideum is required for phagocytosis and cell motility

(2013) Rolf Müller et al.   Cell Communication and Signaling

Met synergizes with p53 loss to induce mammary tumors that possess features of claudin-low breast cancer

(2013) J. F. Knight et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

BRAG2/GEP100/IQSec1 Interacts with Clathrin and Regulates α5β1 Integrin Endocytosis through Activation of ADP Ribosylation Factor 5 (Arf5)

(2012) Radim Moravec et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Phosphoinositide specificity determines which cytohesins regulate β1 integrin recycling

(2012) Seung Ja Oh et al.   JOURNAL OF CELL SCIENCE

Met receptor tyrosine kinase signals through a cortactin–Gab1 scaffold complex, to mediate invadopodia

(2012) Charles V. Rajadurai et al.   JOURNAL OF CELL SCIENCE

Dynamics of receptor trafficking in tumorigenicity

(2012) Christine A. Parachoniak et al.   TRENDS IN CELL BIOLOGY

GGA3 Functions as a Switch to Promote Met Receptor Recycling, Essential for Sustained ERK and Cell Migration

(2011) Christine Anna Parachoniak et al.   DEVELOPMENTAL CELL

Cytohesin-1 regulates human blood neutrophil adhesion to endothelial cells through β2 integrin activation

(2011) Mohammed-Amine El azreq et al.   MOLECULAR IMMUNOLOGY

ARF family G proteins and their regulators: roles in membrane transport, development and disease

(2011) Julie G. Donaldson et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Dorsal Ruffle Microdomains Potentiate Met Receptor Tyrosine Kinase Signaling and Down-regulation

(2010) Jasmine V. Abella et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

Differential Effects of Cytohesins 2 and 3 on β1 Integrin Recycling

(2010) Seung Ja Oh et al.   JOURNAL OF BIOLOGICAL CHEMISTRY

ADP-Ribosylation Factor 6 Regulates Tumorigenic and Invasive Properties In vivo

(2009) V. Muralidharan-Chari et al.   CANCER RESEARCH

Discovery of New Cargo Proteins that Enter Cells through Clathrin-Independent Endocytosis

(2009) Craig A. Eyster et al.   TRAFFIC

Endocytic Trafficking of Rac Is Required for the Spatial Restriction of Signaling in Cell Migration

(2008) Andrea Palamidessi et al.   CELL

Deep surveying of alternative splicing complexity in the human transcriptome by high-throughput sequencing

(2008) Qun Pan et al.   NATURE GENETICS