Retromer Ensures the Degradation of Autophagic Cargo by Maintaining Lysosome Function in Drosophila

How and why to study autophagy in Drosophila: It’s more than just a garbage chute

(2015) Péter Nagy et al.   METHODS

Retromer Binding to FAM21 and the WASH Complex Is Perturbed by the Parkinson Disease-Linked VPS35(D620N) Mutation

(2014) Ian J. McGough et al.   CURRENT BIOLOGY

Retromer-dependent neurotransmitter receptor trafficking to synapses is altered by the Parkinson's disease VPS35 mutation p.D620N

(2014) L. N. Munsie et al.   HUMAN MOLECULAR GENETICS

Parkinson's disease-linked mutations in VPS35 induce dopaminergic neurodegeneration

(2014) E. Tsika et al.   HUMAN MOLECULAR GENETICS

Interaction of the HOPS complex with Syntaxin 17 mediates autophagosome clearance in Drosophila

(2014) Szabolcs Takáts et al.   MOLECULAR BIOLOGY OF THE CELL

Role of Endosomes and Lysosomes in Human Disease

(2014) F. R. Maxfield   Cold Spring Harbor Perspectives in Biology

Mutation in VPS35 associated with Parkinson’s disease impairs WASH complex association and inhibits autophagy

(2014) Eszter Zavodszky et al.   Nature Communications

In vivo evidence of pathogenicity of VPS35 mutations in the Drosophila

(2014) Hua-shan Wang et al.   Molecular Brain

The Retromer Complex Is Required for Rhodopsin Recycling and Its Loss Leads to Photoreceptor Degeneration

(2014) Shiuan Wang et al.   PLOS BIOLOGY

Atg6/UVRAG/Vps34-Containing Lipid Kinase Complex Is Required for Receptor Downregulation through Endolysosomal Degradation and Epithelial Polarity duringDrosophilaWing Development

(2014) Péter Lőrincz et al.   Biomed Research International

Endosomal recruitment of the WASH complex: Active sequences and mutations impairing interaction with the retromer

(2013) Emmanuèle Helfer et al.   BIOLOGY OF THE CELL

Membrane remodeling by the PX-BAR protein SNX18 promotes autophagosome formation

(2013) Helene Knævelsrud et al.   JOURNAL OF CELL BIOLOGY

Autophagosomal Syntaxin17-dependent lysosomal degradation maintains neuronal function inDrosophila

(2013) Szabolcs Takáts et al.   JOURNAL OF CELL BIOLOGY

Retromer Promotes Immune Quiescence by Suppressing Spätzle-Toll Pathway inDrosophila

(2013) Bo Zhou et al.   JOURNAL OF CELLULAR PHYSIOLOGY

The Mechanism and Physiological Function of Macroautophagy

(2013) Daniel J. Klionsky et al.   Journal of Innate Immunity

Rab11 facilitates cross-talk between autophagy and endosomal pathway through regulation of Hook localization

(2013) Zsuzsanna Szatmári et al.   MOLECULAR BIOLOGY OF THE CELL

A global analysis of SNX27–retromer assembly and cargo specificity reveals a function in glucose and metal ion transport

(2013) Florian Steinberg et al.   NATURE CELL BIOLOGY

The Vps35 D620N Mutation Linked to Parkinson's Disease Disrupts the Cargo Sorting Function of Retromer

(2013) Jordan Follett et al.   TRAFFIC

Myc-Driven Overgrowth Requires Unfolded Protein Response-Mediated Induction of Autophagy and Antioxidant Responses in Drosophila melanogaster

(2013) Péter Nagy et al.   PLoS Genetics

Autophagy in lysosomal storage disorders

(2012) Andrew P. Lieberman et al.   Autophagy

Endocytosis and autophagy: Shared machinery for degradation

(2012) Christopher A. Lamb et al.   BIOESSAYS

Type II phosphatidylinositol 4-kinase regulates trafficking of secretory granule proteins in Drosophila

(2012) J. Burgess et al.   DEVELOPMENT

Lysosomal storage disorders: The cellular impact of lysosomal dysfunction

(2012) Frances M. Platt et al.   JOURNAL OF CELL BIOLOGY

The retromer complex - endosomal protein recycling and beyond

(2012) M. N. J. Seaman   JOURNAL OF CELL SCIENCE

The Role of Ceroid Lipofuscinosis Neuronal Protein 5 (CLN5) in Endosomal Sorting

(2012) A. Mamo et al.   MOLECULAR AND CELLULAR BIOLOGY

A Mutation in VPS35, Encoding a Subunit of the Retromer Complex, Causes Late-Onset Parkinson Disease

(2011) Alexander Zimprich et al.   AMERICAN JOURNAL OF HUMAN GENETICS

SNX3 controls Wingless/Wnt secretion through regulating retromer-dependent recycling of Wntless

(2011) Peng Zhang et al.   CELL RESEARCH

Retromer Controls Epithelial Cell Polarity by Trafficking the Apical Determinant Crumbs

(2011) Shirin Meher Pocha et al.   CURRENT BIOLOGY

VPS35 haploinsufficiency increases Alzheimer’s disease neuropathology

(2011) Lei Wen et al.   JOURNAL OF CELL BIOLOGY

Actin polymerization driven by WASH causes V-ATPase retrieval and vesicle neutralization before exocytosis

(2011) Michael Carnell et al.   JOURNAL OF CELL BIOLOGY

Evolutionary reconstruction of the retromer complex and its function in Trypanosoma brucei

(2011) V. L. Koumandou et al.   JOURNAL OF CELL SCIENCE

Autophagic substrate clearance requires activity of the syntaxin-5 SNARE complex

(2011) M. Renna et al.   JOURNAL OF CELL SCIENCE

The reconstructed ancestral subunit a functions as both V-ATPase isoforms Vph1p and Stv1p in Saccharomyces cerevisiae

(2011) Gregory C. Finnigan et al.   MOLECULAR BIOLOGY OF THE CELL

A SNX3-dependent retromer pathway mediates retrograde transport of the Wnt sorting receptor Wntless and is required for Wnt secretion

(2011) Martin Harterink et al.   NATURE CELL BIOLOGY

SNX27 mediates retromer tubule entry and endosome-to-plasma membrane trafficking of signalling receptors

(2011) Paul Temkin et al.   NATURE CELL BIOLOGY

Sorting nexins provide diversity for retromer-dependent trafficking events

(2011) Peter J. Cullen et al.   NATURE CELL BIOLOGY

Drosophila GGA Model: An Ultimate Gateway to GGA Analysis

(2011) Joel C. Eissenberg et al.   TRAFFIC

SNX-BAR-Mediated Endosome Tubulation is Co-ordinated with Endosome Maturation

(2011) Jan R.T. van Weering et al.   TRAFFIC

Autophagic degradation of dBruce controls DNA fragmentation in nurse cells during lateDrosophila melanogasteroogenesis

(2010) Ioannis P. Nezis et al.   JOURNAL OF CELL BIOLOGY

Cell death duringDrosophila melanogasterearly oogenesis is mediated through autophagy

(2009) Ioannis P. Nezis et al.   Autophagy

The Retromer Coat Complex Coordinates Endosomal Sorting and Dynein-Mediated Transport, with Carrier Recognition by the trans-Golgi Network

(2009) Thomas Wassmer et al.   DEVELOPMENTAL CELL

An Atg1/Atg13 Complex with Multiple Roles in TOR-mediated Autophagy Regulation

(2009) Yu-Yun Chang et al.   MOLECULAR BIOLOGY OF THE CELL

Spatial and Functional Relationship of GGAs and AP-1 inDrosophilaand HeLa Cells

(2009) Jennifer Hirst et al.   TRAFFIC

Cathepsin D Is the Main Lysosomal Enzyme Involved in the Degradation of α-Synuclein and Generation of Its Carboxy-Terminally Truncated Species†

(2008) Daniel Sevlever et al.   BIOCHEMISTRY

Autophagy and multivesicular bodies: two closely related partners

(2008) C M Fader et al.   CELL DEATH AND DIFFERENTIATION

Golgi coiled-coil proteins contain multiple binding sites for Rab family G proteins

(2008) Rita Sinka et al.   JOURNAL OF CELL BIOLOGY

The class III PI(3)K Vps34 promotes autophagy and endocytosis but not TOR signaling inDrosophila

(2008) Gábor Juhász et al.   JOURNAL OF CELL BIOLOGY

Regulation of retromer recruitment to endosomes by sequential action of Rab5 and Rab7

(2008) Raul Rojas et al.   JOURNAL OF CELL BIOLOGY

Wingless secretion requires endosome-to-Golgi retrieval of Wntless/Evi/Sprinter by the retromer complex

(2008) Xavier Franch-Marro et al.   NATURE CELL BIOLOGY

Endosomal sorting and signalling: an emerging role for sorting nexins

(2008) Peter J. Cullen   NATURE REVIEWS MOLECULAR CELL BIOLOGY

Retromer deficiency observed in Alzheimer's disease causes hippocampal dysfunction, neurodegeneration, and A  accumulation

(2008) A. Muhammad et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA