P53-dependent induction of ferroptosis is required for artemether to alleviate carbon tetrachloride-induced liver fibrosis and hepatic stellate cell activation

Heme oxygenase-1 mediates BAY 11–7085 induced ferroptosis

(2018) Ling-Chu Chang et al.   CANCER LETTERS

p53 Suppresses Metabolic Stress-Induced Ferroptosis in Cancer Cells

(2018) Amy Tarangelo et al.   Cell Reports

Iron accumulation in senescent cells is coupled with impaired ferritinophagy and inhibition of ferroptosis

(2018) Shashank Masaldan et al.   Redox Biology

The origin of fibrogenic myofibroblasts in fibrotic liver

(2017) Tatiana Kisseleva   HEPATOLOGY

Tetramethylpyrazine attenuates sinusoidal angiogenesis via inhibition of hedgehog signaling in liver fibrosis

(2017) Shifeng Zhao et al.   IUBMB LIFE

Oroxylin A prevents angiogenesis of LSECs in liver fibrosis via inhibition of YAP/HIF-1α signaling

(2017) Chenxi Zhang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Development and in vitro/in vivo evaluation of artemether and lumefantrine co-loaded nanoliposomes for parenteral delivery

(2017) Kashif Shakeel et al.   JOURNAL OF LIPOSOME RESEARCH

Interaction between autophagy and senescence is required for dihydroartemisinin to alleviate liver fibrosis

(2017) Zili Zhang et al.   Cell Death & Disease

The Tumor Suppressor p53 Limits Ferroptosis by Blocking DPP4 Activity

(2017) Yangchun Xie et al.   Cell Reports

The African-specific S47 polymorphism of p53 alters chemosensitivity

(2016) Subhasree Basu et al.   CELL CYCLE

Ferroptosis: process and function

(2016) Y Xie et al.   CELL DEATH AND DIFFERENTIATION

Mechanisms of ferroptosis

(2016) Jennifer Yinuo Cao et al.   CELLULAR AND MOLECULAR LIFE SCIENCES

The characteristics of activated portal fibroblasts/myofibroblasts in liver fibrosis

(2016) Daniel Karin et al.   DIFFERENTIATION

ROS-JNK1/2-dependent activation of autophagy is required for the induction of anti-inflammatory effect of dihydroartemisinin in liver fibrosis

(2016) Zili Zhang et al.   FREE RADICAL BIOLOGY AND MEDICINE

Metallothionein-1G facilitates sorafenib resistance through inhibition of ferroptosis

(2016) Xiaofang Sun et al.   HEPATOLOGY

Ironing out how p53 regulates ferroptosis

(2016) Maureen E. Murphy   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Ferroptosis: Death by Lipid Peroxidation

(2016) Wan Seok Yang et al.   TRENDS IN CELL BIOLOGY

Activation of PPARγ/P53 signaling is required for curcumin to induce hepatic stellate cell senescence

(2016) H Jin et al.   Cell Death & Disease

Loss of p53-mediated cell-cycle arrest, senescence and apoptosis promotes genomic instability and premature aging

(2016) Tongyuan Li et al.   Oncotarget

Acetylation Is Crucial for p53-Mediated Ferroptosis and Tumor Suppression

(2016) Shang-Jui Wang et al.   Cell Reports

Targeting the PDGF-B/PDGFR-β Interface with Destruxin A5 to Selectively Block PDGF-BB/PDGFR-ββ Signaling and Attenuate Liver Fibrosis

(2016) Xingqi Wang et al.   EBioMedicine

The retinoblastoma (Rb) protein regulates ferroptosis induced by sorafenib in human hepatocellular carcinoma cells

(2015) Christophe Louandre et al.   CANCER LETTERS

Dynamic roles of p53-mediated metabolic activities in ROS-induced stress responses

(2015) Le Jiang et al.   CELL CYCLE

Ferroptosis in p53-dependent oncosuppression and organismal homeostasis

(2015) L Galluzzi et al.   CELL DEATH AND DIFFERENTIATION

Activation of the p62-Keap1-NRF2 pathway protects against ferroptosis in hepatocellular carcinoma cells

(2015) Xiaofang Sun et al.   HEPATOLOGY

Mechanisms of liver fibrosis resolution

(2015) Frank Tacke et al.   JOURNAL OF HEPATOLOGY

Glutaminolysis and Transferrin Regulate Ferroptosis

(2015) Minghui Gao et al.   MOLECULAR CELL

Mutant p53 and chromatin regulation

(2015) Carol Prives et al.   NATURE

Ferroptosis as a p53-mediated activity during tumour suppression

(2015) Le Jiang et al.   NATURE

HSPB1 as a novel regulator of ferroptotic cancer cell death

(2015) X Sun et al.   ONCOGENE

Regulation of Ferroptotic Cancer Cell Death by GPX4

(2014) Wan Seok Yang et al.   CELL

Inactivation of the ferroptosis regulator Gpx4 triggers acute renal failure in mice

(2014) Jose Pedro Friedmann Angeli et al.   NATURE CELL BIOLOGY

Conditional loss of heparin-binding EGF-like growth factor results in enhanced liver fibrosis after bile duct ligation in mice

(2013) Takayo Takemura et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS

Curcumin modulates cannabinoid receptors in liver fibrosis in vivo and inhibits extracellular matrix expression in hepatic stellate cells by suppressing cannabinoid receptor type-1 in vitro

(2013) Zili Zhang et al.   EUROPEAN JOURNAL OF PHARMACOLOGY

NLRP3 inflammasome activation results in hepatocyte pyroptosis, liver inflammation, and fibrosis in mice

(2013) Alexander Wree et al.   HEPATOLOGY

Ferroptosis: An Iron-Dependent Form of Nonapoptotic Cell Death

(2012) Scott J. Dixon et al.   CELL

Artemether and Artesunate Show the Highest Efficacies in Rescuing Mice with Late-Stage Cerebral Malaria and Rapidly Decrease Leukocyte Accumulation in the Brain

(2011) L. Clemmer et al.   ANTIMICROBIAL AGENTS AND CHEMOTHERAPY

Antitumor and immunomodulatory properties of artemether and its ability to reduce CD4+ CD25+ FoxP3+ T reg cells in vivo

(2011) Vida Farsam et al.   INTERNATIONAL IMMUNOPHARMACOLOGY

Celecoxib induces hepatic stellate cell apoptosis through inhibition of Akt activation and suppresses hepatic fibrosis in rats

(2009) Y-H Paik et al.   GUT