Tetramethylpyrazine attenuates sinusoidal angiogenesis via inhibition of hedgehog signaling in liver fibrosis

Plants and their active compounds: natural molecules to target angiogenesis

(2016) Kai Lu et al.   ANGIOGENESIS

Ligustrazine for the Treatment of Unstable Angina: A Meta-Analysis of 16 Randomized Controlled Trials

(2016) Suman Cao et al.   Evidence-based Complementary and Alternative Medicine

Hepatic expression of Sonic Hedgehog induces liver fibrosis and promotes hepatocarcinogenesis in a transgenic mouse model

(2016) Sook In Chung et al.   JOURNAL OF HEPATOLOGY

Sinusoidal communication in liver fibrosis and regeneration

(2016) Giusi Marrone et al.   JOURNAL OF HEPATOLOGY

Beneficial Effects of Silymarin After the Discontinuation of CCl4-Induced Liver Fibrosis

(2016) Simona Clichici et al.   JOURNAL OF MEDICINAL FOOD

Reactive oxygen species and synthetic antioxidants as angiogenesis modulators: Clinical implications

(2016) Dorota M. Radomska-Leśniewska et al.   Pharmacological Reports

“Decoding” Angiogenesis: New Facets Controlling Endothelial Cell Behavior

(2016) Raj Sewduth et al.   Frontiers in Physiology

The Annexin a2 Promotes Development in Arthritis through Neovascularization by Amplification Hedgehog Pathway

(2016) Jun Yi et al.   PLoS One

Isolation and co-culture of rat parenchymal and non-parenchymal liver cells to evaluate cellular interactions and response

(2016) Shyam Sundhar Bale et al.   Scientific Reports

ADAMTS3 activity is mandatory for embryonic lymphangiogenesis and regulates placental angiogenesis

(2015) Lauriane Janssen et al.   ANGIOGENESIS

Novel Oxazolidinone Antibacterial Analogues with a Substituted Ligustrazine C-ring Unit

(2015) Yan Chen et al.   Chemical Biology & Drug Design

Resolution of liver fibrosis requires myeloid cell-driven sinusoidal angiogenesis

(2015) Chahrazade Kantari-Mimoun et al.   HEPATOLOGY

Inhibition of hedgehog signaling ameliorates hepatic inflammation in mice with nonalcoholic fatty liver disease

(2015) Hyunjoo Kwon et al.   HEPATOLOGY

Liver sinusoidal endothelial cells in hepatic fibrosis

(2015) Laurie D. DeLeve   HEPATOLOGY

Tetramethylpyrazine reduces inflammation in liver fibrosis and inhibits inflammatory cytokine expression in hepatic stellate cells by modulating NLRP3 inflammasome pathway

(2015) Xiafei Wu et al.   IUBMB LIFE

Mechanisms of liver fibrosis resolution

(2015) Frank Tacke et al.   JOURNAL OF HEPATOLOGY

Curcumin regulates cell fate and metabolism by inhibiting hedgehog signaling in hepatic stellate cells

(2015) Naqi Lian et al.   LABORATORY INVESTIGATION

Inhibition of notch signaling pathway prevents cholestatic liver fibrosis by decreasing the differentiation of hepatic progenitor cells into cholangiocytes

(2015) Xiao Zhang et al.   LABORATORY INVESTIGATION

Pivotal role of liver sinusoidal endothelial cells in NAFLD/NASH progression

(2015) Masashi Miyao et al.   LABORATORY INVESTIGATION

Targeting vascular and leukocyte communication in angiogenesis, inflammation and fibrosis

(2015) Johan Kreuger et al.   NATURE REVIEWS DRUG DISCOVERY

Herbal formula, Scutellariae radix and Rhei rhizoma attenuate dimethylnitrosamine-induced liver fibrosis in a rat model

(2015) Tai-Long Pan et al.   Scientific Reports

Neurons Limit Angiogenesis by Titrating VEGF in Retina

(2014) Keisuke Okabe et al.   CELL

Tetramethylpyrazine inhibits angiotensin II-induced activation of hepatic stellate cells associated with interference of platelet-derived growth factor β receptor pathways

(2014) Xiaoping Zhang et al.   FEBS Journal

CCL2-dependent infiltrating macrophages promote angiogenesis in progressive liver fibrosis

(2014) Josef Ehling et al.   GUT

Cost-effectiveness of noninvasive liver fibrosis tests for treatment decisions in patients with chronic hepatitis C

(2014) Emmanuel A. Tsochatzis et al.   HEPATOLOGY

Curcumin attenuates angiogenesis in liver fibrosis and inhibits angiogenic properties of hepatic stellate cells

(2014) Feng Zhang et al.   JOURNAL OF CELLULAR AND MOLECULAR MEDICINE

Cultured mycelium Cordyceps sinensis protects liver sinusoidal endothelial cells in acute liver injured mice

(2014) Yuan Peng et al.   MOLECULAR BIOLOGY REPORTS

Dosage-Dependent Regulation of Pancreatic Cancer Growth and Angiogenesis by Hedgehog Signaling

(2014) Esha Mathew et al.   Cell Reports

Paracrine signals from liver sinusoidal endothelium regulate hepatitis C virus replication

(2013) Ian A. Rowe et al.   HEPATOLOGY

Peroxisome proliferator-activated receptor-  interrupts angiogenic signal transduction by transrepression of platelet-derived growth factor-  receptor in hepatic stellate cells

(2013) F. Zhang et al.   JOURNAL OF CELL SCIENCE

Astrocyte-Derived Sonic Hedgehog Contributes to Angiogenesis in Brain Microvascular Endothelial Cells via RhoA/ROCK Pathway After Oxygen–Glucose Deprivation

(2013) Quan-Wei He et al.   MOLECULAR NEUROBIOLOGY

Divergent angiocrine signals from vascular niche balance liver regeneration and fibrosis

(2013) Bi-Sen Ding et al.   NATURE

Antithrombotic activity of HY023016, a novel Dabigatran prodrug evaluated in animal thrombosis models

(2013) Yun-Zhan Li et al.   THROMBOSIS RESEARCH

Curcumin ameliorates intrahepatic angiogenesis and capillarization of the sinusoids in carbon tetrachloride-induced rat liver fibrosis

(2013) Qunyan Yao et al.   TOXICOLOGY LETTERS

Hedgehog signalling regulates liver sinusoidal endothelial cell capillarisation

(2012) Guanhua Xie et al.   GUT

Hedgehog signalling and LSEC capillarisation: stopping this one in its tracks

(2012) Heather Francis et al.   GUT

Combined Therapy with Sonic Hedgehog Gene Transfer and Bone Marrow-Derived Endothelial Progenitor Cells Enhances Angiogenesis and Myogenesis in the Ischemic Skeletal Muscle

(2012) Mariangela Palladino et al.   JOURNAL OF VASCULAR RESEARCH

PDGF-BB modulates hematopoiesis and tumor angiogenesis by inducing erythropoietin production in stromal cells

(2011) Yuan Xue et al.   NATURE MEDICINE

Platelet-derived thrombospondin-1 is a critical negative regulator and potential biomarker of angiogenesis

(2010) A. Zaslavsky et al.   BLOOD

Ligustrazine inhibits B16F10 melanoma metastasis and suppresses angiogenesis induced by Vascular Endothelial Growth Factor

(2009) Lei Chen et al.   BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS