Disordered Regions of Mixed Lineage Leukemia 4 (MLL4) Protein Are Capable of RNA Binding

Expression levels of long non-coding RNAs are prognostic for AML outcome

(2018) Arvind Singh Mer et al.   Journal of Hematology & Oncology

IUPred2A: context-dependent prediction of protein disorder as a function of redox state and protein binding

(2018) Bálint Mészáros et al.   NUCLEIC ACIDS RESEARCH

BeStSel: a web server for accurate protein secondary structure prediction and fold recognition from the circular dichroism spectra

(2018) András Micsonai et al.   NUCLEIC ACIDS RESEARCH

mRNA structure determines specificity of a polyQ-driven phase separation

(2018) Erin M. Langdon et al.   SCIENCE

The Long Noncoding RNA MEG3 and its Target miR-147 Regulate JAK/STAT Pathway in Advanced Chronic Myeloid Leukemia

(2018) Zi-ye Li et al.   EBioMedicine

Long non-coding RNAs: The novel diagnostic biomarkers for leukemia

(2017) Shaoyun Chen et al.   ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY

Histone methylase MLL1 coordinates with HIF and regulate lncRNA HOTAIR expression under hypoxia

(2017) Arunoday Bhan et al.   GENE

Over-expressed long noncoding RNA HOXA11-AS promotes cell cycle progression and metastasis in gastric cancer

(2017) Zhili Liu et al.   Molecular Cancer

Biomolecular condensates: organizers of cellular biochemistry

(2017) Salman F. Banani et al.   NATURE REVIEWS MOLECULAR CELL BIOLOGY

The interaction of lncRNA EZR-AS1 with SMYD3 maintains overexpression of EZR in ESCC cells

(2017) Xiao-Dan Zhang et al.   NUCLEIC ACIDS RESEARCH

The non-coding RNA landscape of human hematopoiesis and leukemia

(2017) Adrian Schwarzer et al.   Nature Communications

Long non-coding RNA PARTICLE bridges histone and DNA methylation

(2017) Valerie Bríd O’Leary et al.   Scientific Reports

Long Non-Coding RNAs: Key Regulators of Epithelial-Mesenchymal Transition, Tumour Drug Resistance and Cancer Stem Cells

(2017) Richard Heery et al.   Cancers

Intrinsic protein disorder in histone lysine methylation

(2016) Tamas Lazar et al.   Biology Direct

Long noncoding RNAs in cancer: mechanisms of action and technological advancements

(2016) Nenad Bartonicek et al.   Molecular Cancer

The Snail repressor recruits EZH2 to specific genomic sites through the enrollment of the lncRNA HOTAIR in epithelial-to-mesenchymal transition

(2016) C Battistelli et al.   ONCOGENE

Role of HOTAIR in the diagnosis and prognosis of acute leukemia

(2016) Yuan-Yuan Zhang et al.   ONCOLOGY REPORTS

MLL3/MLL4/COMPASS Family on Epigenetic Regulation of Enhancer Function and Cancer

(2016) Christie C. Sze et al.   Cold Spring Harbor Perspectives in Medicine

Toward a Consensus on the Binding Specificity and Promiscuity of PRC2 for RNA

(2015) Chen Davidovich et al.   MOLECULAR CELL

RNA Controls PolyQ Protein Phase Transitions

(2015) Huaiying Zhang et al.   MOLECULAR CELL

The landscape of long noncoding RNAs in the human transcriptome

(2015) Matthew K Iyer et al.   NATURE GENETICS

High-throughput prediction of RNA, DNA and protein binding regions mediated by intrinsic disorder

(2015) Zhenling Peng et al.   NUCLEIC ACIDS RESEARCH

Accurate secondary structure prediction and fold recognition for circular dichroism spectroscopy

(2015) András Micsonai et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

The recruitment of chromatin modifiers by long noncoding RNAs: lessons from PRC2

(2015) Chen Davidovich et al.   RNA

PARTICLE, a Triplex-Forming Long ncRNA, Regulates Locus-Specific Methylation in Response to Low-Dose Irradiation

(2015) Valerie Bríd O’Leary et al.   Cell Reports

The lncRNA Firre anchors the inactive X chromosome to the nucleolus by binding CTCF and maintains H3K27me3 methylation

(2015) Fan Yang et al.   GENOME BIOLOGY

Regulatory Interactions between RNA and Polycomb Repressive Complex 2

(2014) Catherine Cifuentes-Rojas et al.   MOLECULAR CELL

COSMIC: exploring the world's knowledge of somatic mutations in human cancer

(2014) Simon A. Forbes et al.   NUCLEIC ACIDS RESEARCH

A long noncoding RNA critically regulates Bcr-Abl-mediated cellular transformation by acting as a competitive endogenous RNA

(2014) G Guo et al.   ONCOGENE

A framework for organizing cancer-related variations from existing databases, publications and NGS data using a High-performance Integrated Virtual Environment (HIVE)

(2014) Tsung-Jung Wu et al.   Database-The Journal of Biological Databases and Curation

Essential role of lncRNA binding for WDR5 maintenance of active chromatin and embryonic stem cell pluripotency

(2014) Yul W Yang et al.   eLife

The NeST Long ncRNA Controls Microbial Susceptibility and Epigenetic Activation of the Interferon-γ Locus

(2013) J. Antonio Gomez et al.   CELL

A novel long non-coding RNA T-ALL-R-LncR1 knockdown and Par-4 cooperate to induce cellular apoptosis in T-cell acute lymphoblastic leukemia cells

(2013) Lin Zhang et al.   LEUKEMIA & LYMPHOMA

Promiscuous RNA binding by Polycomb repressive complex 2

(2013) Chen Davidovich et al.   NATURE STRUCTURAL & MOLECULAR BIOLOGY

Enhancer-associated H3K4 monomethylation by Trithorax-related, the Drosophila homolog of mammalian Mll3/Mll4

(2012) H.-M. Herz et al.   GENES & DEVELOPMENT

Overexpression of the long non-coding RNA MEG3 impairs in vitro glioma cell proliferation

(2012) Pengjun Wang et al.   JOURNAL OF CELLULAR BIOCHEMISTRY

Histone modification: cause or cog?

(2011) Steven Henikoff et al.   TRENDS IN GENETICS

Phosphorylation of the PRC2 component Ezh2 is cell cycle-regulated and up-regulates its binding to ncRNA

(2010) S. Kaneko et al.   GENES & DEVELOPMENT

Long Noncoding RNA as Modular Scaffold of Histone Modification Complexes

(2010) M.-C. Tsai et al.   SCIENCE

Many human large intergenic noncoding RNAs associate with chromatin-modifying complexes and affect gene expression

(2009) Ahmad M. Khalil et al.   PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA

Prediction of Protein Binding Regions in Disordered Proteins

(2009) Bálint Mészáros et al.   PLoS Computational Biology